Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice R Gordon, EA Albornoz, DC Christie, MR Langley, V Kumar, S Mantovani, ... Science translational medicine 10 (465), eaah4066, 2018 | 585 | 2018 |
The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins V Deora, JD Lee, EA Albornoz, L McAlary, CJ Jagaraj, AAB Robertson, ... Glia 68 (2), 407-421, 2020 | 156 | 2020 |
Fyn kinase regulates microglial neuroinflammatory responses in cell culture and animal models of Parkinson's disease N Panicker, H Saminathan, H Jin, M Neal, DS Harischandra, R Gordon, ... Journal of Neuroscience 35 (27), 10058-10077, 2015 | 150 | 2015 |
The complement receptor C5aR controls acute inflammation and astrogliosis following spinal cord injury FH Brennan, R Gordon, HW Lao, PJ Biggins, SM Taylor, RJM Franklin, ... Journal of Neuroscience 35 (16), 6517-6531, 2015 | 119 | 2015 |
Prokineticin‐2 promotes chemotaxis and alternative A2 reactivity of astrocytes M Neal, J Luo, DS Harischandra, R Gordon, S Sarkar, H Jin, ... Glia 66 (10), 2137-2157, 2018 | 106 | 2018 |
Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease R Gordon, N Singh, V Lawana, A Ghosh, DS Harischandra, H Jin, ... Neurobiology of disease 93, 96-114, 2016 | 100 | 2016 |
A simple magnetic separation method for high-yield isolation of pure primary microglia R Gordon, CE Hogan, ML Neal, V Anantharam, AG Kanthasamy, ... Journal of neuroscience methods 194 (2), 287-296, 2011 | 100 | 2011 |
Specific inhibition of NLRP3 in chikungunya disease reveals a role for inflammasomes in alphavirus-induced inflammation W Chen, SS Foo, A Zaid, TS Teng, LJ Herrero, S Wolf, K Tharmarajah, ... Nature microbiology 2 (10), 1435-1445, 2017 | 93 | 2017 |
Proteolytic activation of proapoptotic kinase protein kinase Cδ by tumor necrosis factor α death receptor signaling in dopaminergic neurons during neuroinflammation R Gordon, V Anantharam, AG Kanthasamy, A Kanthasamy Journal of neuroinflammation 9, 1-18, 2012 | 93 | 2012 |
Prokineticin-2 upregulation during neuronal injury mediates a compensatory protective response against dopaminergic neuronal degeneration R Gordon, ML Neal, J Luo, MR Langley, DS Harischandra, N Panicker, ... Nature communications 7 (1), 12932, 2016 | 90 | 2016 |
An overview of sleep and circadian dysfunction in Parkinson's disease S Mantovani, SS Smith, R Gordon, JD O'Sullivan Journal of Sleep Research 27 (3), e12673, 2018 | 84 | 2018 |
Elevation of the terminal complement activation products C5a and C5b-9 in ALS patient blood S Mantovani, R Gordon, JK Macmaw, CMM Pfluger, RD Henderson, ... Journal of Neuroimmunology 276 (1-2), 213-218, 2014 | 77 | 2014 |
Antiallodynic effects of alpha lipoic acid in an optimized RR‐EAE mouse model of MS‐neuropathic pain are accompanied by attenuation of upregulated BDNF‐TrkB‐ERK signaling in … N Khan, R Gordon, TM Woodruff, MT Smith Pharmacology research & perspectives 3 (3), e00137, 2015 | 49 | 2015 |
Neuroprotective effect of resveratrol against methamphetamine-induced dopaminergic apoptotic cell death in a cell culture model of neurotoxicity K Kanthasamy, R Gordon, H Jin, V Anantharam, S Ali, A G Kanthasamy, ... Current neuropharmacology 9 (1), 49-53, 2011 | 46 | 2011 |
Inflammasomes in CNS diseases EA Albornoz, TM Woodruff, R Gordon Inflammasomes: Clinical and Therapeutic Implications, 41-60, 2018 | 40 | 2018 |
The ketone body β-hydroxybutyrate does not inhibit synuclein mediated inflammasome activation in microglia V Deora, EA Albornoz, K Zhu, TM Woodruff, R Gordon Journal of Neuroimmune Pharmacology 12, 568-574, 2017 | 32 | 2017 |
Motor deficits associated with Huntington's disease occur in the absence of striatal degeneration in BACHD transgenic mice S Mantovani, R Gordon, R Li, DC Christie, V Kumar, TM Woodruff Human Molecular Genetics 25 (9), 1780-1791, 2016 | 29 | 2016 |
p73 gene in dopaminergic neurons is highly susceptible to manganese neurotoxicity DS Kim, H Jin, V Anantharam, R Gordon, A Kanthasamy, AG Kanthasamy Neurotoxicology 59, 231-239, 2017 | 18 | 2017 |
Neuroinflammation as a Therapeutic Target in Neurodegenerative Diseases R Gordon, TM Woodruff Disease-Modifying Targets in Neurodegenerative Disorders 1, 89-132, 2017 | 14 | 2017 |
Interaction of the brain-selective sulfotransferase SULT4A1 with other cytosolic sulfotransferases: effects on protein expression and function M Idris, DJ Mitchell, R Gordon, NP Sidharthan, NJ Butcher, RF Minchin Drug Metabolism and Disposition 48 (5), 337-344, 2020 | 10 | 2020 |