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Chau De Ming
Chau De Ming
memorial sloan-kettering, universiti putra malaysia
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Year
An APP inhibitory domain containing the Flemish mutation residue modulates γ-secretase activity for Aβ production
Y Tian, B Bassit, D Chau, YM Li
Nature structural & molecular biology 17 (2), 151-158, 2010
1182010
Modulation of γ-secretase specificity using small molecule allosteric inhibitors
CC Shelton, L Zhu, D Chau, L Yang, R Wang, H Djaballah, H Zheng, ...
Proceedings of the National Academy of Sciences 106 (48), 20228-20233, 2009
1002009
Piperidine acetic acid based γ-secretase modulators directly bind to Presenilin-1
CJ Crump, BA Fish, SV Castro, DM Chau, N Gertsik, K Ahn, C Stiff, ...
ACS chemical neuroscience 2 (12), 705-710, 2011
762011
Familial Alzheimer disease presenilin-1 mutations alter the active site conformation of γ-secretase
DM Chau, CJ Crump, JC Villa, DA Scheinberg, YM Li
Journal of Biological Chemistry 287 (21), 17288-17296, 2012
732012
Development of clickable active site-directed photoaffinity probes for γ-secretase
CJ Crump, CW am Ende, TE Ballard, N Pozdnyakov, M Pettersson, ...
Bioorganic & medicinal chemistry letters 22 (8), 2997-3000, 2012
372012
A novel high throughput 1536-well Notch1 γ-secretase AlphaLISA assay
DM Chau, D Shum, C Radu, B Bhinder, D Gin, ML Gilchrist, H Djaballah, ...
Combinatorial chemistry & high throughput screening 16 (6), 415-424, 2013
212013
Non-natural and photo-reactive amino acids as biochemical probes of immune function
M Gomez-Nunez, KJ Haro, T Dao, D Chau, A Won, S Escobar-Alvarez, ...
PLoS One 3 (12), e3938, 2008
202008
γ-secretase inhibitors and modulators induce distinct conformational changes in the active sites of γ-secretase and signal peptide peptidase
N Gertsik, DM Chau, YM Li
ACS chemical biology 10 (8), 1925-1931, 2015
182015
Malaysian educational module on responsible conduct of research
DM Chau, LC Chai, A Veerakumarasivam
Kuala Lumpur (Malaysia): Academy of Sciences Malaysia, 2018
112018
Expression Profiling of Notch Signalling Pathway and Gamma-Secretase Activity in the Brain of Ts1Cje Mouse Model of Down Syndrome
HH Yusof, HC Lee, EA Seth, X Wu, CA Hewitt, HS Scott, PS Cheah, YM Li, ...
Journal of Molecular Neuroscience 67, 632-642, 2019
52019
Photo-Reactive and Non-Natural Amino Acid Epitopes of Human WT1 Enhance Immunogenicity and Allow Kinetic Study of Antigen Processing.
KJ Haro, M Gomez-Nunez, T Dao, D Chau, A Won, S Escobar-Alvarez, ...
Blood, The Journal of the American Society of Hematology 110 (11), 2311-2311, 2007
42007
A comprehensive review of cystic fibrosis in Africa and Asia
KA Bobbo, U Ahmad, DM Chau, N Nordin, S Abdullah
Saudi journal of biological sciences, 103685, 2023
22023
Make research-integrity education fun and relevant
D Chau
Nature 587 (7832), 9-9, 2020
22020
Mainstreaming responsible conduct of research education in Malaysia
DM Chau, LC Chai, MS Cheema, A Veerakumarasivam
Forensic Sciences Research 6 (4), 338-340, 2021
12021
Integrating active learning and content localisation in the delivery of responsible conduct of research education in Malaysia
LC Chai, DM Chau, A Veerakumarasivam
HIGHER EDUCATION AS AN ENTERPRISE–EMBEDDING THE QUALITY ASSURANCE CULTURE, 13, 2021
12021
Functional Transcriptome Analysis of Bladder Cancer Cell Lines Persistently Infected with Oncolytic Newcastle Disease Virus
U Ahmad, A Thirumorthy, DM Chau, SL Chia, K Yusoff, S Abdullah, ...
bioRxiv, 2020.12. 14.422610, 2020
12020
Methods and compositions for gamma-secretase assay
YM Li, DM Chau, JC Villa, C Crump
US Patent 9,632,088, 2017
12017
Differential Protein Expression Patterns of HOXA13 and HOXB13 Are Associated with Bladder Cancer Progression
FW Chin, H Hussin, DM Chau, TA Ong, R Yunus, AH Abdul Razack, ...
Diagnostics 13 (16), 2636, 2023
2023
Analysis of PPI networks of transcriptomic expression identifies hub genes associated with Newcastle disease virus persistent infection in bladder cancer
U Ahmad, S Abdullah, DM Chau, SL Chia, K Yusoff, SC Chan, TA Ong, ...
Scientific Reports 13 (1), 7323, 2023
2023
EMBEDDING RESEARCH INTEGRITY TO ENSURE QUALITY OF HIGHER EDUCATION IN MALAYSIA
DM Chau, LC Chai, A Veerakumarasivam
HIGHER EDUCATION AS AN ENTERPRISE–EMBEDDING THE QUALITY ASSURANCE CULTURE, 81, 2021
2021
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