A chemical and phosphoproteomic characterization of dasatinib action in lung cancer J Li, U Rix, B Fang, Y Bai, A Edwards, J Colinge, KL Bennett, J Gao, ... Nature chemical biology 6 (4), 291-299, 2010 | 292 | 2010 |
Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation K Mahajan, D Coppola, S Challa, B Fang, YA Chen, W Zhu, AS Lopez, ... PloS one 5 (3), e9646, 2010 | 169 | 2010 |
HDAC6 deacetylates and ubiquitinates MSH2 to maintain proper levels of MutSα M Zhang, S Xiang, HY Joo, L Wang, KA Williams, W Liu, C Hu, D Tong, ... Molecular cell 55 (1), 31-46, 2014 | 120 | 2014 |
Tyrosine Phosphoproteomics Identifies Both Codrivers and Cotargeting Strategies for T790M-Related EGFR-TKI Resistance in Non–Small Cell Lung CancerPhosphoproteomics of EGFR-TKI … T Yoshida, G Zhang, MA Smith, AS Lopez, Y Bai, J Li, B Fang, J Koomen, ... Clinical Cancer Research 20 (15), 4059-4074, 2014 | 110 | 2014 |
Phosphoproteomics identifies driver tyrosine kinases in sarcoma cell lines and tumors Y Bai, J Li, B Fang, A Edwards, G Zhang, M Bui, S Eschrich, S Altiok, ... Cancer research 72 (10), 2501-2511, 2012 | 108 | 2012 |
Dissection of TBK1 signaling via phosphoproteomics in lung cancer cells JY Kim, EA Welsh, U Oguz, B Fang, Y Bai, F Kinose, C Bronk, ... Proceedings of the National Academy of Sciences 110 (30), 12414-12419, 2013 | 105 | 2013 |
H2B Tyr37 phosphorylation suppresses expression of replication-dependent core histone genes K Mahajan, B Fang, JM Koomen, NP Mahajan Nature structural & molecular biology 19 (9), 930-937, 2012 | 100 | 2012 |
Extracellular signal-regulated kinase (ERK) phosphorylates histone deacetylase 6 (HDAC6) at serine 1035 to stimulate cell migration KA Williams, M Zhang, S Xiang, C Hu, JY Wu, S Zhang, M Ryan, AD Cox, ... Journal of Biological Chemistry 288 (46), 33156-33170, 2013 | 99 | 2013 |
SIRT1 negatively regulates the activities, functions, and protein levels of hMOF and TIP60 L Peng, H Ling, Z Yuan, B Fang, G Bloom, K Fukasawa, J Koomen, ... Molecular and cellular biology 32 (14), 2823-2836, 2012 | 97 | 2012 |
Ligand-Independent EPHA2 Signaling Drives the Adoption of a Targeted Therapy–Mediated Metastatic Melanoma PhenotypeEphA2-Mediated Metastasis KHT Paraiso, MD Thakur, B Fang, JM Koomen, IV Fedorenko, JK John, ... Cancer discovery 5 (3), 264-273, 2015 | 91 | 2015 |
Fibronectin induction abrogates the BRAF inhibitor response of BRAF V600E/PTEN-null melanoma cells IV Fedorenko, EV Abel, JM Koomen, B Fang, ER Wood, YA Chen, ... Oncogene 35 (10), 1225-1235, 2016 | 88 | 2016 |
Molecular mechanism of glyceraldehyde-3-phosphate dehydrogenase inactivation by α, β-unsaturated carbonyl derivatives CJ Martyniuk, B Fang, JM Koomen, T Gavin, L Zhang, DS Barber, ... Chemical research in toxicology 24 (12), 2302-2311, 2011 | 81 | 2011 |
Mass spectrometry mapping of epidermal growth factor receptor phosphorylation related to oncogenic mutations and tyrosine kinase inhibitor sensitivity G Zhang, B Fang, RZ Liu, H Lin, F Kinose, Y Bai, U Oguz, ... Journal of proteome research 10 (1), 305-319, 2011 | 72 | 2011 |
Activation of the unfolded protein response contributes toward the antitumor activity of vorinostat S Kahali, B Sarcar, B Fang, ES Williams, JM Koomen, PJ Tofilon, ... Neoplasia 12 (1), 80-86, 2010 | 66 | 2010 |
Ubiquitinated sirtuin 1 (SIRT1) function is modulated during DNA damage-induced cell death and survival L Peng, Z Yuan, Y Li, H Ling, V Izumi, B Fang, K Fukasawa, J Koomen, ... Journal of Biological Chemistry 290 (14), 8904-8912, 2015 | 60 | 2015 |
Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms J Li, K Bennett, A Stukalov, B Fang, G Zhang, T Yoshida, I Okamoto, ... Molecular systems biology 9 (1), 705, 2013 | 50 | 2013 |
Adaptive Responses to Dasatinib-Treated Lung Squamous Cell Cancer Cells Harboring DDR2 MutationsDDR2 Phosphoproteomics in Lung SCC Y Bai, JY Kim, JM Watters, B Fang, F Kinose, L Song, JM Koomen, ... Cancer research 74 (24), 7217-7228, 2014 | 46 | 2014 |
GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation JK John, KHT Paraiso, VW Rebecca, LP Cantini, EV Abel, N Pagano, ... Journal of investigative dermatology 132 (12), 2818-2827, 2012 | 43 | 2012 |
Critical role of Shp2 in tumor growth involving regulation of c-Myc Y Ren, Z Chen, L Chen, B Fang, H Win-Piazza, E Haura, JM Koomen, ... Genes & cancer 1 (10), 994-1007, 2010 | 42 | 2010 |
Oxadiazole-isopropylamides as potent and noncovalent proteasome inhibitors S Ozcan, A Kazi, F Marsilio, B Fang, WC Guida, J Koomen, HR Lawrence, ... Journal of medicinal chemistry 56 (10), 3783-3805, 2013 | 38 | 2013 |