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Crystal S Conn
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Differential requirements for eIF4E dose in normal development and cancer
ML Truitt, CS Conn, Z Shi, X Pang, T Tokuyasu, AM Coady, Y Seo, ...
Cell 162 (1), 59-71, 2015
3482015
Oncogenic KRAS regulates amino acid homeostasis and asparagine biosynthesis via ATF4 and alters sensitivity to L-asparaginase
DM Gwinn, AG Lee, M Briones-Martin-del-Campo, CS Conn, DR Simpson, ...
Cancer cell 33 (1), 91-107. e6, 2018
1922018
ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression
F Tameire, II Verginadis, NM Leli, C Polte, CS Conn, R Ojha, ...
Nature cell biology 21 (7), 889-899, 2019
1892019
Development of a stress response therapy targeting aggressive prostate cancer
HG Nguyen, CS Conn, Y Kye, L Xue, CM Forester, JE Cowan, AC Hsieh, ...
Science translational medicine 10 (439), eaar2036, 2018
1462018
Ribosomal proteins regulate MHC class I peptide generation for immunosurveillance
J Wei, RJ Kishton, M Angel, CS Conn, N Dalla-Venezia, V Marcel, ...
Molecular cell 73 (6), 1162-1173. e5, 2019
932019
Nutrient signaling in protein homeostasis: an increase in quantity at the expense of quality
CS Conn, SB Qian
Science signaling 6 (271), ra24-ra24, 2013
782013
mTOR signaling in protein homeostasis: less is more?
CS Conn, SB Qian
Cell cycle 10 (12), 1940-1947, 2011
752011
Translational control of the cytosolic stress response by mitochondrial ribosomal protein L18
X Zhang, X Gao, RA Coots, CS Conn, B Liu, SB Qian
Nature structural & molecular biology 22 (5), 404-410, 2015
662015
PI3K-mTORC1 attenuates stress response by inhibiting cap-independent Hsp70 translation
J Sun, CS Conn, Y Han, V Yeung, SB Qian
Journal of Biological Chemistry 286 (8), 6791-6800, 2011
552011
The major cap-binding protein eIF4E regulates lipid homeostasis and diet-induced obesity
CS Conn, H Yang, HJ Tom, K Ikeda, JA Oses-Prieto, H Vu, Y Oguri, S Nair, ...
Nature metabolism 3 (2), 244-257, 2021
352021
Noninvasive Measurement of mTORC1 Signaling with 89Zr-Transferrin
C Truillet, JT Cunningham, MFL Parker, LT Huynh, CS Conn, D Ruggero, ...
Clinical Cancer Research 23 (12), 3045-3052, 2017
262017
PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy
D Zhang, AM Li, G Hu, M Huang, F Yang, L Zhang, KE Wellen, X Xu, ...
Cell Metabolism 35 (3), 517-534. e8, 2023
222023
Reduced eIF4E function impairs B-cell leukemia without altering normal B-lymphocyte function
H Chiu, R Buono, LV Jackson, L Herzog, S Mallya, CS Conn, D Ruggero, ...
Iscience 24 (7), 2021
72021
The integrated stress response in cancer progression: A force for plasticity and resistance
CL Lines, MJ McGrath, T Dorwart, CS Conn
Frontiers in Oncology 13, 2023
42023
Viewing folding of nascent polypeptide chains from ribosomes
B Liu, CS Conn, SB Qian
Expert review of proteomics 9 (6), 579-581, 2012
32012
Cancer Treatment Targeted to Tumor Adaptive Responses to Protein Synthesis Stress
D Ruggero, H Nguyen, P Carroll, C Conn
US Patent App. 17/576,623, 2022
2022
Cancer treatment targeted to tumor adaptive responses to protein synthesis stress
D Ruggero, H Nguyen, P Carroll, C Conn
US Patent 11,253,522, 2022
2022
eIF4E selective control for metabolic fitness and healthspan
CS Conn, H Yang, K Ikeda, JA Oses-Prieto, S Nair, M Parker, PB Ventura, ...
MOLECULAR & CELLULAR PROTEOMICS 18 (8), S76-S76, 2019
2019
Abstract A25: Sensing stress in cancer: a novel therapy targeting protein synthesis through the unfolded protein response in prostate cancer development
CS Conn, HG Nguyen, Y Kye, JT Cunningham, C Truillet, M Evans, ...
Cancer Research 77 (6_Supplement), A25-A25, 2017
2017
Sensing stress in cancer: a novel therapy targeting protein synthesis through the unfolded protein response in prostate cancer development
CS Conn, HG Nguyen, Y Kye, JT Cunningham, C Truillet, M Evans, ...
CANCER RESEARCH 77, 2017
2017
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Articles 1–20