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Rajan Guha ,PhD
Rajan Guha ,PhD
Senior Scientist , AstraZeneca
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
Vaccination with Leishmania Hemoglobin Receptor–Encoding DNA Protects Against Visceral Leishmaniasis
R Guha, D Gupta, R Rastogi, R Vikram, G Krishnamurthy, S Bimal, S Roy, ...
Science Translational Medicine 5 (202), 202ra121-202ra121, 2013
702013
A molecular signature in blood reveals a role for p53 in regulating malaria-induced inflammation
TM Tran, R Guha, S Portugal, J Skinner, A Ongoiba, J Bhardwaj, M Jones, ...
Immunity 51 (4), 750-765. e10, 2019
692019
Hyperlipidemia offers protection against Leishmania donovani infection: role of membrane cholesterol [S]
J Ghosh, S Das, R Guha, D Ghosh, K Naskar, A Das, S Roy
Journal of Lipid Research 53 (12), 2560-2572, 2012
622012
Synthesis, characterization and in vitro cytotoxicity assessment of hydroxyapatite from different bioresources for tissue engineering application
S Mondal, R Bardhan, B Mondal, A Dey, SS Mukhopadhyay, S Roy, ...
Bulletin of materials science 35, 683-691, 2012
592012
Heterologous priming–boosting with DNA and vaccinia virus expressing kinetoplastid membrane protein-11 induces potent cellular immune response and confers protection against …
R Guha, S Das, J Ghosh, K Naskar, A Mandala, S Sundar, JC Dujardin, ...
Vaccine 31 (15), 1905-1915, 2013
482013
Plasmodium falciparum malaria drives epigenetic reprogramming of human monocytes toward a regulatory phenotype
R Guha, A Mathioudaki, S Doumbo, D Doumtabe, J Skinner, G Arora, ...
PLoS pathogens 17 (4), e1009430, 2021
462021
Designing therapies against experimental visceral leishmaniasis by modulating the membrane fluidity of antigen-presenting cells
S Banerjee, J Ghosh, S Sen, R Guha, R Dhar, M Ghosh, S Datta, ...
Infection and immunity 77 (6), 2330-2342, 2009
422009
Liposomal cholesterol delivery activates the macrophage innate immune arm to facilitate intracellular Leishmania donovani killing
J Ghosh, R Guha, S Das, S Roy
Infection and immunity 82 (2), 607-617, 2014
402014
Antimony Resistant Leishmania donovani but Not Sensitive Ones Drives Greater Frequency of Potent T-Regulatory Cells upon Interaction with Human PBMCs …
R Guha, S Das, J Ghosh, S Sundar, JC Dujardin, S Roy
PLoS neglected tropical diseases 8 (7), e2995, 2014
272014
PD-1 expression on NK cells in malaria-exposed individuals is associated with diminished natural cytotoxicity and enhanced antibody-dependent cellular cytotoxicity
J Moebius, R Guha, M Peterson, K Abdi, J Skinner, S Li, G Arora, B Traore, ...
Infection and Immunity 88 (3), 10.1128/iai. 00711-19, 2020
182020
Vaccination with leishmania hemoglobin receptor-encoding DNA protects against visceral leishmaniasis. Sci. Transl. Med. 2013; 5 (202): 202ra121
R Guha, D Gupta, R Rastogi, R Vikram, G Krishnamurthy, S Bimal
Immunization with HbR-DNA induced sterile protection against L. donovani …, 0
6
Emerging therapeutic modalities against malaria
SK Chalapareddy, A Sajid, M Saxena, K Arora, R Guha, G Arora
Translational Biotechnology, 267-286, 2021
42021
Evolutionarily Selected Overexpression of the Cytokine BAFF Enhances Mucosal Immune Response Against P. falciparum
V Lodde, M Floris, I Beerman, R Munk, R Guha, M Steri, V Orrù, ...
Frontiers in Immunology 11, 575103, 2020
42020
Repeated febrile malaria exposure remodels monocytes/macrophages toward a regulatory/tolerogenic phenotype
R Guha, A Mathioudaki, G Arora, S Li, S Siddiqui, D Doumtabe, ...
The Journal of Immunology 204 (1_Supplement), 67.7-67.7, 2020
2020
Repeated malaria exposures associate with skewing of monocytes/macrophages toward a regulatory phenotype
R Guha, G Arora, S Li, D Doumtabe, S Doumbo, K Kayentao, A Ongoiba, ...
The Journal of Immunology 202 (1_Supplement), 126.7-126.7, 2019
2019
REPEATED MALARIA EXPOSURES SKEW MONOCYTES/MACROPHAGES TOWARDS A REGULATORY PHENOTYPE
R Guha, A Mathioudaki, G Arora, S Li, S Siddiqui, J Skinner, D Doumtabe, ...
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 101, 201-201, 2019
2019
Hemoglobin receptor as novel vaccine for leishmaniasis
A Mukhopadhyay, S Roy, D Gupta, G Rajan, R Rastogi
US Patent 9,764,015, 2017
2017
Testing the hypothesis that malaria-induced immune remodeling of monocytes plays a role in immunity to malaria
R Guha, PD Crompton
The Journal of Immunology 198 (1_Supplement), 70.7-70.7, 2017
2017
Leishmania Gets Schooled
R Guha, D Gupta, R Rastogi, R Vikram, G Krishnamurthy, S Bimal, S Roy, ...
SCIENCE TRANSLATIONAL MEDICINE 5 (202), 2013
2013
Dissecting the Cellular Immune Response in Visceral Leishmaniasis
R Guha
Jadavpur University, 2012
2012
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