Cavities determine the pressure unfolding of proteins J Roche, JA Caro, DR Norberto, P Barthe, C Roumestand, JL Schlessman, ... Proceedings of the National Academy of Sciences 109 (18), 6945-6950, 2012 | 437 | 2012 |
Monomeric Aβ1–40 and Aβ1–42 Peptides in Solution Adopt Very Similar Ramachandran Map Distributions That Closely Resemble Random Coil J Roche, Y Shen, JH Lee, J Ying, A Bax Biochemistry 55 (5), 762-775, 2016 | 200 | 2016 |
Homonuclear decoupling for enhancing resolution and sensitivity in NOE and RDC measurements of peptides and proteins J Ying, J Roche, A Bax Journal of Magnetic Resonance 241, 97-102, 2014 | 136 | 2014 |
Size and sequence and the volume change of protein folding JB Rouget, T Aksel, J Roche, JL Saldana, AE Garcia, D Barrick, CA Royer Journal of the American Chemical Society 133 (15), 6020-6027, 2011 | 127 | 2011 |
Local unfolding of the HSP27 monomer regulates chaperone activity TR Alderson, J Roche, HY Gastall, DM Dias, I Pritišanac, J Ying, A Bax, ... Nature communications 10 (1), 1068, 2019 | 106 | 2019 |
Lessons from pressure denaturation of proteins J Roche, CA Royer Journal of the Royal Society Interface 15 (147), 20180244, 2018 | 106 | 2018 |
ScanFold: an approach for genome-wide discovery of local RNA structural elements—applications to Zika virus and HIV RJ Andrews, J Roche, WN Moss PeerJ 6, e6136, 2018 | 80 | 2018 |
Improved cross validation of a static ubiquitin structure derived from high precision residual dipolar couplings measured in a drug-based liquid crystalline phase AS Maltsev, A Grishaev, J Roche, M Zasloff, A Bax Journal of the American Chemical Society 136 (10), 3752-3755, 2014 | 78 | 2014 |
Effect of internal cavities on folding rates and routes revealed by real-time pressure-jump NMR spectroscopy J Roche, M Dellarole, JA Caro, DR Norberto, AE Garcia, B Garcia-Moreno, ... Journal of the American Chemical Society 135 (39), 14610-14618, 2013 | 76 | 2013 |
Remodeling of the folding free energy landscape of staphylococcal nuclease by cavity-creating mutations J Roche, M Dellarole, JA Caro, E Guca, DR Norberto, Y Yang, AE Garcia, ... Biochemistry 51 (47), 9535-9546, 2012 | 62 | 2012 |
Impact of hydrostatic pressure on an intrinsically disordered protein: a high‐pressure NMR study of α‐Synuclein J Roche, J Ying, AS Maltsev, A Bax ChemBioChem 14 (14), 1754-1761, 2013 | 59 | 2013 |
Monitoring protein folding through high pressure NMR spectroscopy J Roche, CA Royer, C Roumestand Progress in nuclear magnetic resonance spectroscopy 102, 15-31, 2017 | 53 | 2017 |
Dissociation of the trimeric gp41 ectodomain at the lipid–water interface suggests an active role in HIV-1 Env-mediated membrane fusion J Roche, JM Louis, A Grishaev, J Ying, A Bax Proceedings of the National Academy of Sciences 111 (9), 3425-3430, 2014 | 51 | 2014 |
Structural studies of a rationally selected multi-drug resistant HIV-1 protease reveal synergistic effect of distal mutations on flap dynamics J Agniswamy, JM Louis, J Roche, RW Harrison, IT Weber PloS one 11 (12), e0168616, 2016 | 47 | 2016 |
Structural plasticity of staphylococcal nuclease probed by perturbation with pressure and pH R Kitahara, K Hata, A Maeno, K Akasaka, MS Chimenti, ... Proteins: Structure, Function, and Bioinformatics 79 (4), 1293-1305, 2011 | 34 | 2011 |
Conformation of inhibitor‐free HIV‐1 protease derived from nmr spectroscopy in a weakly oriented solution J Roche, JM Louis, A Bax ChemBioChem 16 (2), 214-218, 2015 | 33 | 2015 |
Probing the Physical Determinants of Thermal Expansion of Folded Proteins M Dellarole, K Kobayashi, JB Rouget, JA Caro, J Roche, MM Islam, ... The Journal of Physical Chemistry B 117 (42), 12742-12749, 2013 | 33 | 2013 |
Exploring protein conformational landscapes using high-pressure NMR J Roche, CA Royer, C Roumestand Methods in Enzymology 614, 293-320, 2019 | 31 | 2019 |
Structural, energetic, and dynamic responses of the native state ensemble of staphylococcal nuclease to cavity‐creating mutations J Roche, JA Caro, M Dellarole, E Guca, CA Royer, E García‐Moreno, ... Proteins: Structure, Function, and Bioinformatics 81 (6), 1069-1080, 2013 | 31 | 2013 |
The Energetics of a Three‐State Protein Folding System Probed by High‐Pressure Relaxation Dispersion NMR Spectroscopy V Tugarinov, DS Libich, V Meyer, J Roche, GM Clore Angewandte Chemie International Edition 54 (38), 11157-11161, 2015 | 30 | 2015 |