Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway I Garcia-Higuera, T Taniguchi, S Ganesan, MS Meyn, C Timmers, J Hejna, ... Molecular cell 7 (2), 249-262, 2001 | 1448 | 2001 |
Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma. Y Xu, T Ashley, EE Brainerd, RT Bronson, MS Meyn, D Baltimore Genes & development 10 (19), 2411-2422, 1996 | 1009 | 1996 |
Comprehensive Analysis of Hypermutation in Human Cancer BB Campbell, N Light, D Fabrizio, M Zatzman, F Fuligni, R de Borja, ... Cell 171 (5), 1042-1056. e10, 2017 | 723 | 2017 |
Improved diagnostic yield compared with targeted gene sequencing panels suggests a role for whole-genome sequencing as a first-tier genetic test AC Lionel, G Costain, N Monfared, S Walker, MS Reuter, SM Hosseini, ... Genetics in Medicine 20 (4), 435-443, 2018 | 548 | 2018 |
Ataxia-telangiectasia and cellular responses to DNA damage MS Meyn Cancer research 55 (24), 5991-6001, 1995 | 519 | 1995 |
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers A Shlien, BB Campbell, R de Borja, LB Alexandrov, D Merico, D Wedge, ... Nat Genet 47 (3), 257-262, 2015 | 395 | 2015 |
Whole genome sequencing expands diagnostic utility and improves clinical management in paediatric medicine DJ Stavropoulos, D Merico, R Jobling, S Bowdin, N Monfared, ... npj Genomic Medicine 1 (1), doi:10.1038/npjgenmed.2015.12, 2016 | 381 | 2016 |
The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes. KS Keegan, DA Holtzman, AW Plug, ER Christenson, EE Brainerd, ... Genes & development 10 (19), 2423-2437, 1996 | 346 | 1996 |
A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal M Milyavsky, OI Gan, M Trottier, M Komosa, O Tabach, F Notta, ... Cell Stem Cell 7 (2), 186-197, 2010 | 331 | 2010 |
Phenotypic spectrum associated with de novo and inherited deletions and duplications at 16p11. 2 in individuals ascertained for diagnosis of autism spectrum disorder BA Fernandez, W Roberts, B Chung, R Weksberg, S Meyn, P Szatmari, ... Journal of medical genetics 47 (3), 195-203, 2010 | 331 | 2010 |
The role of Alu repeat clusters as mediators of recurrent chromosomal aberrations in tumors E Kolomietz, MS Meyn, A Pandita, JA Squire Genes, Chromosomes and Cancer 35 (2), 97-112, 2002 | 331 | 2002 |
Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice S Houghtaling, C Timmers, M Noll, MJ Finegold, SN Jones, MS Meyn, ... Genes & development 17 (16), 2021-2035, 2003 | 321 | 2003 |
Human telomeric protein TRF2 associates with genomic double-strand breaks as an early response to DNA damage PS Bradshaw, DJ Stavropoulos, MS Meyn Nature genetics 37 (2), 193-197, 2005 | 300 | 2005 |
High spontaneous intrachromosomal recombination rates in ataxia-telangiectasia MS Meyn Science 260 (5112), 1327-1330, 1993 | 284 | 1993 |
Ataxia-Telangiectasia MS Meyn Chromosomal Instability and Aging: Basic Science and Clinical Implications …, 2003 | 283* | 2003 |
The Bloom syndrome helicase BLM interacts with TRF2 in ALT cells and promotes telomeric DNA synthesis DJ Stavropoulos, PS Bradshaw, X Li, I Pasic, K Truong, M Ikura, M Ungrin, ... Human molecular genetics 11 (25), 3135-3144, 2002 | 250 | 2002 |
PhenoTips: patient phenotyping software for clinical and research use M Girdea, S Dumitriu, M Fiume, S Bowdin, KM Boycott, S Chénier, ... Human mutation 34 (8), 1057-1065, 2013 | 249 | 2013 |
Ataxia‐telangiectasia, cancer and the pathobiology of the ATM gene MS Meyn Clinical genetics 55 (5), 289-304, 1999 | 246 | 1999 |
The clinical application of genome-wide sequencing for monogenic diseases in Canada: Position Statement of the Canadian College of Medical Geneticists K Boycott, T Hartley, S Adam, F Bernier, K Chong, BA Fernandez, ... Journal of Medical Genetics, jmedgenet-2015-103144, 2015 | 225 | 2015 |
Targeted disruption of exons 1 to 6 of the Fanconi Anemia group A gene leads to growth retardation, strain-specific microphthalmia, meiotic defects and primordial germ cell … JCY Wong, N Alon, C Mckerlie, JR Huang, MS Meyn, M Buchwald Human molecular genetics 12 (16), 2063-2076, 2003 | 194 | 2003 |