The role of CSF1R-dependent macrophages in control of the intestinal stem-cell niche A Sehgal, DS Donaldson, C Pridans, KA Sauter, DA Hume, NA Mabbott Nature communications 9 (1), 1272, 2018 | 203 | 2018 |
Pleiotropic effects of extended blockade of CSF1R signaling in adult mice KA Sauter, C Pridans, A Sehgal, YT Tsai, BM Bradford, S Raza, L Moffat, ... Journal of leukocyte biology 96 (2), 265-274, 2014 | 120 | 2014 |
Characterisation of a novel Fc conjugate of macrophage colony-stimulating factor DJ Gow, KA Sauter, C Pridans, L Moffat, A Sehgal, BM Stutchfield, S Raza, ... Molecular Therapy 22 (9), 1580-1592, 2014 | 105 | 2014 |
Aging and the mucosal immune system in the intestine NA Mabbott, A Kobayashi, A Sehgal, BM Bradford, M Pattison, ... Biogerontology 16, 133-145, 2015 | 104 | 2015 |
Functions of macrophage colony-stimulating factor (CSF1) in development, homeostasis, and tissue repair A Sehgal, KM Irvine, DA Hume Seminars in immunology 54, 101509, 2021 | 84 | 2021 |
Development of in vitro enteroids derived from bovine small intestinal crypts CA Hamilton, R Young, S Jayaraman, A Sehgal, E Paxton, S Thomson, ... Veterinary research 49, 1-15, 2018 | 78 | 2018 |
A transgenic line that reports CSF1R protein expression provides a definitive marker for the mouse mononuclear phagocyte system K Grabert, A Sehgal, KM Irvine, E Wollscheid-Lengeling, DD Ozdemir, ... The Journal of Immunology 205 (11), 3154-3166, 2020 | 77 | 2020 |
The MacBlue binary transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to … KA Sauter, C Pridans, A Sehgal, CC Bain, C Scott, L Moffat, R Rojo, ... PLoS One 9 (8), e105429, 2014 | 68 | 2014 |
CSF1R-dependent macrophages control postnatal somatic growth and organ maturation S Keshvari, M Caruso, N Teakle, L Batoon, A Sehgal, OL Patkar, ... PLoS Genetics 17 (6), e1009605, 2021 | 63 | 2021 |
Increased abundance of M cells in the gut epithelium dramatically enhances oral prion disease susceptibility DS Donaldson, A Sehgal, D Rios, IR Williams, NA Mabbott PloS Pathogens 12 (12), e1006075, 2016 | 57 | 2016 |
Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues SM Millard, O Heng, KS Opperman, A Sehgal, KM Irvine, S Kaur, ... Cell reports 37 (8), 2021 | 55 | 2021 |
Analysis of the impact of CSF-1 administration in adult rats using a novel Csf1r-mApple reporter gene KM Irvine, M Caruso, MF Cestari, GM Davis, S Keshvari, A Sehgal, ... Journal of leukocyte biology 107 (2), 221-235, 2020 | 37 | 2020 |
A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling J Stables, EK Green, A Sehgal, OL Patkar, S Keshvari, I Taylor, ... Development 149 (8), dev200237, 2022 | 23 | 2022 |
The mononuclear phagocyte system of the rat DA Hume, M Caruso, S Keshvari, OL Patkar, A Sehgal, SJ Bush, ... The Journal of Immunology 206 (10), 2251-2263, 2021 | 23 | 2021 |
Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice S Kaur, A Sehgal, AC Wu, SM Millard, L Batoon, CJ Sandrock, ... Journal of Hematology & Oncology 14, 1-19, 2021 | 19 | 2021 |
CSF1R as a therapeutic target in bone diseases: obvious but not so simple DA Hume, L Batoon, A Sehgal, S Keshvari, KM Irvine Current Osteoporosis Reports 20 (6), 516-531, 2022 | 12 | 2022 |
c-Rel is dispensable for the differentiation and functional maturation of M cells in the follicle-associated epithelium A Sehgal, A Kobayashi, DS Donaldson, NA Mabbott Immunobiology 222 (2), 316-326, 2017 | 12 | 2017 |
Intraperitoneal transfer of wild‐type bone marrow repopulates tissue macrophages in the Csf1r knockout rat without contributing to monocytopoiesis A Sehgal, D Carter‐Cusack, S Keshvari, O Patkar, S Huang, KM Summers, ... European Journal of Immunology 53 (8), 2250312, 2023 | 5 | 2023 |
Relative contributions of osteal macrophages and osteoclasts to postnatal bone development in CSF1R-deficient rats and phenotype rescue following wild-type bone marrow cell … L Batoon, S Keshvari, KM Irvine, E Ho, M Caruso, OL Patkar, A Sehgal, ... Journal of Leukocyte Biology, qiae077, 2024 | 3 | 2024 |
Wild-type bone marrow cells repopulate tissue resident macrophages and reverse the impacts of homozygous CSF1R mutation D Carter-Cusack, S Huang, S Keshvari, O Patkar, A Sehgal, R Allavena, ... PLoS genetics 21 (1), e1011525, 2025 | 1 | 2025 |