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Joseph R. Testa
Joseph R. Testa
Professor, Fox Chase Cancer Center
Verified email at fccc.edu
Title
Cited by
Cited by
Year
Integrated Genomic Analyses of Ovarian Carcinoma
Nature 474 (7353), 609-615, 2011
68002011
Perturbations of the AKT signaling pathway in human cancer
DA Altomare, JR Testa
Oncogene 24 (50), 7455-7464, 2005
16032005
A Retroviral Oncogene, akt, Encoding a Serine-Threonine Kinase Containing an SH2-Like Region
A Bellacosa, JR Testa, SP Staal, PN Tsichlis
Science 254 (5029), 274-277, 1991
13721991
AKT plays a central role in tumorigenesis
JR Testa, A Bellacosa
Proceedings of the National Academy of Sciences 98 (20), 10983-10985, 2001
12232001
Germline BAP1 mutations predispose to malignant mesothelioma
JR Testa, M Cheung, J Pei, JE Below, Y Tan, E Sementino, NJ Cox, ...
Nature genetics 43 (10), 1022-1025, 2011
11652011
Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas
A Bellacosa, D De Feo, AK Godwin, DW Bell, JQ Cheng, DA Altomare, ...
International journal of cancer 64 (4), 280-285, 1995
11611995
Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA.
JQ Cheng, B Ruggeri, WM Klein, G Sonoda, DA Altomare, DK Watson, ...
Proceedings of the National Academy of Sciences 93 (8), 3636-3641, 1996
10611996
Activation of AKT kinases in cancer: implications for therapeutic targeting
A Bellacosa, CC Kumar, A Di Cristofano, JR Testa
Advances in cancer research 94, 29-86, 2005
10192005
AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas.
JQ Cheng, AK Godwin, A Bellacosa, T Taguchi, TF Franke, TC Hamilton, ...
Proceedings of the National Academy of Sciences 89 (19), 9267-9271, 1992
10051992
BAP1 and cancer
M Carbone, H Yang, HI Pass, T Krausz, JR Testa, G Gaudino
Nature Reviews Cancer 13 (3), 153-159, 2013
6782013
Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E
AC Hsieh, M Costa, O Zollo, C Davis, ME Feldman, JR Testa, O Meyuhas, ...
Cancer cell 17 (3), 249-261, 2010
5322010
Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways
GH Xiao, M Jeffers, A Bellacosa, Y Mitsuuchi, GF Vande Woude, JR Testa
Proceedings of the National Academy of Sciences 98 (1), 247-252, 2001
5162001
AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth
DA Altomare, HQ Wang, KL Skele, AD Rienzo, AJ Klein-Szanto, ...
Oncogene 23 (34), 5853-5857, 2004
4942004
The pathogenesis of mesothelioma
M Carbone, RA Kratzke, JR Testa
Seminars in oncology 29 (1), 2-17, 2002
4882002
p16 Alterations and Deletion Mapping of 9p21–p22 in Malignant Mesothelioma
JQ Cheng, SC Jhanwar, WM Klein, DW Bell, WC Lee, DA Altomare, ...
Cancer research 54 (21), 5547-5551, 1994
4371994
High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas.
AB Bianchi, SI Mitsunaga, JQ Cheng, WM Klein, SC Jhanwar, B Seizinger, ...
Proceedings of the National Academy of Sciences 92 (24), 10854-10858, 1995
4291995
Amplification and overexpression of the AKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas
BA Ruggeri, L Huang, M Wood, JQ Cheng, JR Testa
Molecular Carcinogenesis: Published in cooperation with the University of …, 1998
4211998
p53 Mutations, ras Mutations, and p53-Heat Shock 70 Protein Complexes in Human Lung Carcinoma Cell Lines
TA Lehman, WP Bennett, RA Metcalf, JA Welsh, J Ecker, RV Modali, ...
Cancer research 51 (15), 4090-4096, 1991
4041991
TNF-α inhibits asbestos-induced cytotoxicity via a NF-κB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis
H Yang, M Bocchetta, B Kroczynska, AG Elmishad, Y Chen, Z Liu, ...
Proceedings of the National Academy of Sciences 103 (27), 10397-10402, 2006
3742006
Frequent activation of AKT in non-small cell lung carcinomas and preneoplastic bronchial lesions
BR Balsara, J Pei, Y Mitsuuchi, R Page, A Klein-Szanto, H Wang, ...
Carcinogenesis 25 (11), 2053-2059, 2004
3682004
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