Xiaodong Wang
Xiaodong Wang
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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
P Li, D Nijhawan, I Budihardjo, SM Srinivasula, M Ahmad, ES Alnemri, ...
cell 91 (4), 479-489, 1997
Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c
X Liu, CN Kim, J Yang, R Jemmerson, X Wang
Cell 86 (1), 147-157, 1996
Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked
J Yang, X Liu, K Bhalla, CN Kim, AM Ibrado, J Cai, TI Peng, DP Jones, ...
Science 275 (5303), 1129-1132, 1997
Smac, a mitochondrial protein that promotes cytochrome c–dependent caspase activation by eliminating IAP inhibition
C Du, M Fang, Y Li, L Li, X Wang
Cell 102 (1), 33-42, 2000
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
X Luo, I Budihardjo, H Zou, C Slaughter, X Wang
Cell 94 (4), 481-490, 1998
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c–dependent activation of caspase-3
H Zou, WJ Henzel, X Liu, A Lutschg, X Wang
Cell 90 (3), 405-413, 1997
Biochemical pathways of caspase activation during apoptosis
I Budihardjo, H Oliver, M Lutter, X Luo, X Wang
Annual review of cell and developmental biology 15 (1), 269-290, 1999
The expanding role of mitochondria in apoptosis
X Wang
Genes & development 15 (22), 2922-2933, 2001
An APAF-1 cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
H Zou, Y Li, X Liu, X Wang
Journal of Biological Chemistry 274 (17), 11549-11556, 1999
Endonuclease G is an apoptotic DNase when released from mitochondria
LY Li, X Luo, X Wang
Nature 412 (6842), 95-99, 2001
DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
X Liu, H Zou, C Slaughter, X Wang
Cell 89 (2), 175-184, 1997
Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
L Sun, H Wang, Z Wang, S He, S Chen, D Liao, L Wang, J Yan, W Liu, ...
Cell 148 (1), 213-227, 2012
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-α
S He, L Wang, L Miao, T Wang, F Du, L Zhao, X Wang
Cell 137 (6), 1100-1111, 2009
Cytochrome C-Mediated Apoptosis
X Jiang, X Wang
Annual review of biochemistry 73 (1), 87-106, 2004
TNF-α induces two distinct caspase-8 activation pathways
L Wang, F Du, X Wang
Cell 133 (4), 693-703, 2008
Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3
H Wang, L Sun, L Su, J Rizo, L Liu, LF Wang, FS Wang, X Wang
Molecular cell 54 (1), 133-146, 2014
Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation
D Acehan, X Jiang, DG Morgan, JE Heuser, X Wang, CW Akey
Molecular cell 9 (2), 423-432, 2002
Structural and biochemical basis of apoptotic activation by Smac/DIABLO
J Chai, C Du, JW Wu, S Kyin, X Wang, Y Shi
Nature 406 (6798), 855-862, 2000
SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis
X Wang, R Sato, MS Brown, X Hua, JL Goldstein
Cell 77 (1), 53-62, 1994
Structural basis of IAP recognition by Smac/DIABLO
G Wu, J Chai, TL Suber, JW Wu, C Du, X Wang, Y Shi
Nature 408 (6815), 1008-1012, 2000
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