Hypothalamic KATP channels control hepatic glucose production A Pocai, TKT Lam, R Gutierrez-Juarez, S Obici, GJ Schwartz, J Bryan, ... Nature 434 (7036), 1026-1031, 2005 | 789 | 2005 |
The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species Y Lin, AH Berg, P Iyengar, TKT Lam, A Giacca, TP Combs, MW Rajala, ... Journal of biological chemistry 280 (6), 4617-4626, 2005 | 682 | 2005 |
Hypothalamic sensing of fatty acids TKT Lam, GJ Schwartz, L Rossetti Nature neuroscience 8 (5), 579-584, 2005 | 541 | 2005 |
Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis TKT Lam, A Pocai, R Gutierrez-Juarez, S Obici, J Bryan, L Aguilar-Bryan, ... Nature medicine 11 (3), 320-327, 2005 | 502 | 2005 |
Mechanisms of the free fatty acid-induced increase in hepatic glucose production TKT Lam, A Carpentier, GF Lewis, G van de Werve, IG Fantus, A Giacca American Journal of Physiology-Endocrinology and Metabolism 284 (5), E863-E873, 2003 | 410 | 2003 |
Regulation of blood glucose by hypothalamic pyruvate metabolism TKT Lam, R Gutierrez-Juarez, A Pocai, L Rossetti Science 309 (5736), 943-947, 2005 | 405 | 2005 |
Metformin activates a duodenal Ampk–dependent pathway to lower hepatic glucose production in rats FA Duca, CD Côté, BA Rasmussen, M Zadeh-Tahmasebi, GA Rutter, ... Nature medicine 21 (5), 506-511, 2015 | 398 | 2015 |
Upper intestinal lipids trigger a gut–brain–liver axis to regulate glucose production PYT Wang, L Caspi, CKL Lam, M Chari, X Li, PE Light, R Gutierrez-Juarez, ... Nature 452 (7190), 1012-1016, 2008 | 369 | 2008 |
Regulation of obesity-related insulin resistance with gut anti-inflammatory agents H Luck, S Tsai, J Chung, X Clemente-Casares, M Ghazarian, XS Revelo, ... Cell metabolism 21 (4), 527-542, 2015 | 358 | 2015 |
N-acetylcysteine and taurine prevent hyperglycemia-induced insulin resistance in vivo: possible role of oxidative stress CA Haber, TKT Lam, Z Yu, N Gupta, T Goh, E Bogdanovic, A Giacca, ... American Journal of Physiology-Endocrinology and Metabolism 285 (4), E744-E753, 2003 | 336 | 2003 |
Free fatty acid-induced hepatic insulin resistance: a potential role for protein kinase C-δ TKT Lam, H Yoshii, CA Haber, E Bogdanovic, L Lam, IG Fantus, A Giacca American Journal of Physiology-Endocrinology and Metabolism 283 (4), E682-E691, 2002 | 279 | 2002 |
Molecular disruption of hypothalamic nutrient sensing induces obesity W He, TKT Lam, S Obici, L Rossetti Nature neuroscience 9 (2), 227-233, 2006 | 263 | 2006 |
Jejunal nutrient sensing is required for duodenal-jejunal bypass surgery to rapidly lower glucose concentrations in uncontrolled diabetes DM Breen, BA Rasmussen, A Kokorovic, R Wang, GWC Cheung, ... Nature medicine 18 (6), 950-955, 2012 | 255 | 2012 |
Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats A Pocai, TKT Lam, S Obici, R Gutierrez-Juarez, ED Muse, A Arduini, ... The Journal of clinical investigation 116 (4), 1081-1091, 2006 | 253 | 2006 |
Metformin alters upper small intestinal microbiota that impact a glucose-SGLT1-sensing glucoregulatory pathway PV Bauer, FA Duca, TMZ Waise, BA Rasmussen, MA Abraham, ... Cell Metabolism 27 (1), 101-117. e5, 2018 | 244 | 2018 |
Free fatty acids increase basal hepatic glucose production and induce hepatic insulin resistance at different sites TKT Lam, G Van de Werve, A Giacca American Journal of Physiology-Endocrinology And Metabolism 284 (2), E281-E290, 2003 | 222 | 2003 |
Intestinal cholecystokinin controls glucose production through a neuronal network GWC Cheung, A Kokorovic, CKL Lam, M Chari, TKT Lam Cell metabolism 10 (2), 99-109, 2009 | 204 | 2009 |
Brain glucose metabolism controls the hepatic secretion of triglyceride-rich lipoproteins TKT Lam, R Gutierrez-Juarez, A Pocai, S Bhanot, P Tso, GJ Schwartz, ... Nature medicine 13 (2), 171-180, 2007 | 173 | 2007 |
CNS regulation of glucose homeostasis CKL Lam, M Chari, TKT Lam Physiology 24 (3), 159-170, 2009 | 158 | 2009 |
Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network CD Côté, BA Rasmussen, FA Duca, M Zadeh-Tahmasebi, JA Baur, ... Nature medicine 21 (5), 498-505, 2015 | 153 | 2015 |