Diego Sepulveda-Falla
Diego Sepulveda-Falla
Group Leader, Molecular Neuropathology of Alzheimer's Disease, UKE, Hamburg
Verified email at - Homepage
Cited by
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Discriminative accuracy of plasma phospho-tau217 for Alzheimer disease vs other neurodegenerative disorders
S Palmqvist, S Janelidze, YT Quiroz, H Zetterberg, F Lopera, E Stomrud, ...
Jama 324 (8), 772-781, 2020
Pre-dementia clinical stages in presenilin 1 E280A familial early-onset Alzheimer's disease: a retrospective cohort study
N Acosta-Baena, D Sepulveda-Falla, CM Lopera-Gómez, ...
The Lancet Neurology 10 (3), 213-220, 2011
Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer’s disease
J Rasmussen, J Mahler, N Beschorner, SA Kaeser, LM Häsler, ...
Proceedings of the National Academy of Sciences 114 (49), 13018-13023, 2017
Qualitative changes in human γ-secretase underlie familial Alzheimer’s disease
M Szaruga, S Veugelen, M Benurwar, S Lismont, D Sepulveda-Falla, ...
Journal of Experimental Medicine 212 (12), 2003-2013, 2015
The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2
S Krasemann, U Haferkamp, S Pfefferle, MS Woo, F Heinrich, ...
Stem cell reports 17 (2), 307-320, 2022
Familial Alzheimer’s disease–associated presenilin-1 alters cerebellar activity and calcium homeostasis
D Sepulveda-Falla, A Barrera-Ocampo, C Hagel, A Korwitz, ...
The Journal of clinical investigation 124 (4), 1552-1567, 2014
High molecular mass assemblies of amyloid-β oligomers bind prion protein in patients with Alzheimer’s disease
F Dohler, D Sepulveda-Falla, S Krasemann, H Altmeppen, H Schlüter, ...
Brain 137 (3), 873-886, 2014
Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease
M Pera, D Alcolea, R Sánchez-Valle, C Guardia-Laguarta, ...
Acta Neuropathologica 125, 201-213, 2013
APOE* E2 allele delays age of onset in PSEN1 E280A Alzheimer’s disease
JI Vélez, F Lopera, D Sepulveda-Falla, HR Patel, AS Johar, A Chuah, ...
Molecular psychiatry 21 (7), 916-924, 2016
Plasma neurofilament light chain in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional and longitudinal cohort study
YT Quiroz, H Zetterberg, EM Reiman, Y Chen, Y Su, JT Fox-Fuller, ...
The Lancet Neurology 19 (6), 513-521, 2020
C455R notch3 mutation in a Colombian CADASIL kindred with early onset of stroke
JF Arboleda–Velasquez, F Lopera, E Lopez, MP Frosch, ...
Neurology 59 (2), 277-279, 2002
Complement 3+-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia
K Hartmann, D Sepulveda-Falla, IVL Rose, C Madore, C Muth, ...
Acta Neuropathologica Communications 7 (1), 1-15, 2019
Deposition of hyperphosphorylated tau in cerebellum of PS1 E280A Alzheimer's disease
D Sepulveda‐Falla, J Matschke, C Bernreuther, C Hagel, B Puig, ...
Brain pathology 21 (4), 452-463, 2011
Phenotypic profile of early-onset familial Alzheimer's disease caused by presenilin-1 E280A mutation
D Sepulveda-Falla, M Glatzel, F Lopera
Journal of Alzheimer's Disease 32 (1), 1-12, 2012
A genetic cluster of early onset Parkinson's disease in a Colombian population
N Pineda‐Trujillo, M Apergi, S Moreno, W Arias, S Lesage, A Franco, ...
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 141 …, 2006
A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer’s disease
D Sepulveda-Falla, L Chavez-Gutierrez, E Portelius, JI Vélez, S Dujardin, ...
Acta neuropathologica 141, 217-233, 2021
Phagocytosis of apoptotic cells is specifically upregulated in ApoE4 expressing microglia in vitro
C Muth, A Hartmann, D Sepulveda-Falla, M Glatzel, S Krasemann
Frontiers in cellular neuroscience 13, 181, 2019
Immune activation in amyloid-β-related angiitis correlates with decreased parenchymal amyloid-β plaque load
S Bogner, C Bernreuther, J Matschke, A Barrera-Ocampo, ...
Neurodegenerative Diseases 13 (1), 38-44, 2013
Resilience to autosomal dominant Alzheimer’s disease in a Reelin-COLBOS heterozygous man
F Lopera, C Marino, AS Chandrahas, M O’Hare, ND Villalba-Moreno, ...
Nature Medicine, 1-10, 2023
Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer’s dementia
D Sepulveda-Falla, JS Sanchez, MC Almeida, D Boassa, J Acosta-Uribe, ...
Acta Neuropathologica 144 (3), 589-601, 2022
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