| Phosphoinositide-mediated oligomerization of a defensin induces cell lysis IKH Poon, AA Baxter, FT Lay, GD Mills, CG Adda, JAE Payne, TK Phan, ... Elife 3, e01808, 2014 | 193 | 2014 |
| Convergent evolution of defensin sequence, structure and function TMA Shafee, FT Lay, TK Phan, MA Anderson, MD Hulett Cellular and Molecular Life Sciences 74, 663-682, 2017 | 177 | 2017 |
| Moving beyond size and phosphatidylserine exposure: evidence for a diversity of apoptotic cell-derived extracellular vesicles in vitro IKH Poon, MAF Parkes, L Jiang, GK Atkin-Smith, R Tixeira, CD Gregory, ... Journal of extracellular vesicles 8 (1), 1608786, 2019 | 113 | 2019 |
| Determining the contents and cell origins of apoptotic bodies by flow cytometry L Jiang, S Paone, S Caruso, GK Atkin-Smith, TK Phan, MD Hulett, ... Scientific reports 7 (1), 14444, 2017 | 108 | 2017 |
| The tomato defensin TPP3 binds phosphatidylinositol (4, 5)-bisphosphate via a conserved dimeric cationic grip conformation to mediate cell lysis AA Baxter, V Richter, FT Lay, IKH Poon, CG Adda, PK Veneer, TK Phan, ... Molecular and cellular biology 35 (11), 1964-1978, 2015 | 97 | 2015 |
| Staphylococcus aureus membrane vesicles contain immunostimulatory DNA, RNA and peptidoglycan that activate innate immune receptors and induce autophagy NJ Bitto, L Cheng, EL Johnston, R Pathirana, TK Phan, IKH Poon, ... Journal of extracellular vesicles 10 (6), e12080, 2021 | 91 | 2021 |
| Isolation of cell type-specific apoptotic bodies by fluorescence-activated cell sorting GK Atkin-Smith, S Paone, DJ Zanker, M Duan, TK Phan, W Chen, ... Scientific reports 7 (1), 39846, 2017 | 84 | 2017 |
| X-ray structure of a carpet-like antimicrobial defensin–phospholipid membrane disruption complex M Järvå, FT Lay, TK Phan, C Humble, IKH Poon, MR Bleackley, ... Nature communications 9 (1), 1962, 2018 | 64 | 2018 |
| The relationship between CCR6 and its binding partners: Does the CCR6–CCL20 axis have to be extended? AYS Lee, TK Phan, MD Hulett, H Körner Cytokine 72 (1), 97-101, 2015 | 59 | 2015 |
| Unleashing the therapeutic potential of apoptotic bodies TK Phan, DC Ozkocak, IKH Poon Biochemical society transactions 48 (5), 2079-2088, 2020 | 55 | 2020 |
| ROCK1 but not LIMK1 or PAK2 is a key regulator of apoptotic membrane blebbing and cell disassembly R Tixeira, TK Phan, S Caruso, B Shi, GK Atkin-Smith, C Nedeva, ... Cell Death & Differentiation 27 (1), 102-116, 2020 | 54 | 2020 |
| Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death AA Baxter, TK Phan, E Hanssen, M Liem, MD Hulett, S Mathivanan, ... Scientific reports 9 (1), 7538, 2019 | 54 | 2019 |
| Human β-defensin 3 contains an oncolytic motif that binds PI (4, 5) P2 to mediate tumour cell permeabilisation TK Phan, FT Lay, IKH Poon, MG Hinds, M Kvansakul, MD Hulett Oncotarget 7 (2), 2054, 2016 | 54 | 2016 |
| Salt-tolerant antifungal and antibacterial activities of the corn defensin ZmD32 BK Kerenga, JA McKenna, PJ Harvey, P Quimbar, D Garcia-Ceron, ... Frontiers in Microbiology 10, 795, 2019 | 52 | 2019 |
| Human MAIT cell cytolytic effector proteins synergize to overcome carbapenem resistance in Escherichia coli C Boulouis, WR Sia, MY Gulam, JQM Teo, YT Png, TK Phan, JYW Mak, ... PLoS biology 18 (6), e3000644, 2020 | 51 | 2020 |
| Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin–lipid oligomeric assemblies and membrane permeabilization M Kvansakul, FT Lay, CG Adda, PK Veneer, AA Baxter, TK Phan, ... Proceedings of the National Academy of Sciences 113 (40), 11202-11207, 2016 | 51 | 2016 |
| Human β-defensin 2 kills Candida albicans through phosphatidylinositol 4,5-bisphosphate–mediated membrane permeabilization M Järvå, TK Phan, FT Lay, S Caria, M Kvansakul, MD Hulett Science Advances 4 (7), eaat0979, 2018 | 50 | 2018 |
| Phosphoinositides: multipurpose cellular lipids with emerging roles in cell death TK Phan, SA Williams, GK Bindra, FT Lay, IKH Poon, MD Hulett Cell Death & Differentiation 26 (5), 781-793, 2019 | 44 | 2019 |
| TREML4 receptor regulates inflammation and innate immune cell death during polymicrobial sepsis C Nedeva, J Menassa, M Duan, C Liu, M Doerflinger, AJ Kueh, MJ Herold, ... Nature immunology 21 (12), 1585-1596, 2020 | 43 | 2020 |
| Gasdermin E does not limit apoptotic cell disassembly by promoting early onset of secondary necrosis in Jurkat T cells and THP-1 monocytes R Tixeira, BO Shi, MAF Parkes, AL Hodge, S Caruso, MD Hulett, ... Frontiers in immunology 9, 2842, 2018 | 39 | 2018 |
Mark HulettLa Trobe Institute for Molecular ScienceVerified email at latrobe.edu.au
