Design, synthesis and evaluation of novel multi-target-directed ligands for treatment of Alzheimer's disease based on coumarin and lipoic acid scaffolds L Jalili-Baleh, H Forootanfar, TT Küçükkılınç, H Nadri, Z Abdolahi, A Ameri, ... European journal of medicinal chemistry 152, 600-614, 2018 | 69 | 2018 |
Ketamine induces rapid and sustained antidepressant-like effects in chronic pain induced depression: Role of MAPK signaling pathway M Humo, B Ayazgök, LJ Becker, E Waltisperger, T Rantamäki, I Yalcin Progress in Neuro-Psychopharmacology and Biological Psychiatry 100, 109898, 2020 | 47 | 2020 |
Novel 3-phenylcoumarin–lipoic acid conjugates as multi-functional agents for potential treatment of Alzheimer's disease L Jalili-Baleh, H Nadri, H Forootanfar, A Samzadeh-Kermani, ... Bioorganic chemistry 79, 223-234, 2018 | 42 | 2018 |
Novel multi-targeted agents for Alzheimer's disease: Synthesis, biological evaluation, and molecular modeling of novel 2-[4-(4-substitutedpiperazin-1-yl) phenyl] benzimidazoles K Ozadali-Sari, TT Küçükkılınç, B Ayazgok, A Balkan, O Unsal-Tan Bioorganic chemistry 72, 208-214, 2017 | 40 | 2017 |
Synthesis and biological evaluation of new N-benzylpyridinium-based benzoheterocycles as potential anti-Alzheimer’s agents N Salehi, BBF Mirjalili, H Nadri, Z Abdolahi, H Forootanfar, ... Bioorganic Chemistry 83, 559-568, 2019 | 34 | 2019 |
Low‐dose bisphenol A induces RIPK1‐mediated necroptosis in SH‐SY5Y cells: Effects on TNF‐α and acetylcholinesterase B Ayazgök, T Tüylü Küçükkılınç Journal of Biochemical and Molecular Toxicology 33 (1), e22233, 2019 | 22 | 2019 |
New classes of carbazoles as potential multi-functional anti-Alzheimer’s agents N Choubdar, M Golshani, L Jalili-Baleh, H Nadri, TT Küçükkilinç, ... Bioorganic Chemistry 91, 103164, 2019 | 20 | 2019 |
Synthesis and neuroprotective activity of novel 1,2,4-triazine derivatives with ethyl acetate moiety against H 2 O2 and Aβ-induced neurotoxicity T Tuylu Kucukkilinc, K Safari Yanghagh, B Ayazgok, M Ali Roknipour, ... Medicinal Chemistry Research 26, 3057-3071, 2017 | 20 | 2017 |
Chromone–lipoic acid conjugate: Neuroprotective agent having acceptable butyrylcholinesterase inhibition, antioxidant and copper-chelation activities L Jalili-Baleh, H Nadri, H Forootanfar, TT Küçükkılınç, B Ayazgök, ... DARU Journal of Pharmaceutical Sciences 29, 23-38, 2021 | 18 | 2021 |
Novel 2-Arylbenzimidazole derivatives as multi-targeting agents to treat Alzheimer’s disease O Unsal-Tan, K Ozadali-Sari, B Ayazgok, TT Küçükkılınç, A Balkan Medicinal Chemistry Research 26, 1506-1515, 2017 | 17 | 2017 |
The basolateral amygdala-anterior cingulate pathway contributes to depression-like behaviors and comorbidity with chronic pain behaviors in male mice LJ Becker, C Fillinger, R Waegaert, SH Journée, P Hener, B Ayazgok, ... Nature Communications 14 (1), 2198, 2023 | 16 | 2023 |
Design, synthesis, and biological evaluation of novel indanone-based hybrids as multifunctional cholinesterase inhibitors for Alzheimer's disease M Shahrivar-Gargari, M Hamzeh-Mivehroud, S Hemmati, JS Mojarrad, ... Journal of Molecular Structure 1229, 129787, 2021 | 14 | 2021 |
3‐Aryl Coumarin Derivatives Bearing Aminoalkoxy Moiety as Multi‐Target‐Directed Ligands against Alzheimer's Disease H Abdshahzadeh, M Golshani, H Nadri, I Saberi Kia, Z Abdolahi, ... Chemistry & Biodiversity 16 (5), e1800436, 2019 | 13 | 2019 |
Discovery of novel 1, 2, 4-triazolo-1, 2, 4-triazines with thiomethylpyridine hinge binders as potent c-Met kinase inhibitors S Dadashpour, TT Küçükkılınç, B Ayazgök, SJ Hosseinimehr, ... Future Medicinal Chemistry 11 (10), 1119-1136, 2019 | 11 | 2019 |
Düşük Doz Bisfenol A'nın Büyük Etkileri B Ayazgök, TT Küçükkilinç FABAD Journal of Pharmaceutical Sciences 42 (2), 139, 2017 | 11 | 2017 |
Synthesis, molecular docking, and biological evaluation of novel 2-pyrazoline derivatives as multifunctional agents for the treatment of Alzheimer's disease O Unsal-Tan, TT Küçükkılınç, B Ayazgök, A Balkan, K Ozadali-Sari MedChemComm 10 (6), 1018-1026, 2019 | 9 | 2019 |
Synthesis of New 3-Arylcoumarins Bearing N-Benzyl Triazole Moiety: Dual Lipoxygenase and Butyrylcholinesterase Inhibitors With Anti-Amyloid Aggregation and … L Pourabdi, TT Küçükkılınç, F Khoshtale, B Ayazgök, H Nadri, ... Frontiers in Chemistry 9, 810233, 2022 | 7 | 2022 |
Hybridization‐based design of novel anticholinesterase indanone–carbamates for Alzheimer's disease: Synthesis, biological evaluation, and docking studies M Shahrivar‐Gargari, M Hamzeh‐Mivehroud, S Hemmati, JS Mojarrad, ... Archiv der Pharmazie 354 (7), 2000453, 2021 | 7 | 2021 |
Design and Synthesis of 2-Substitutedphenyl Benzo [D] Thiazole Derivatives and Their β-Amyloid Aggregation and Cholinesterase Inhibitory Activities M Zengin, O Unsal-Tan, TT Küçükkılınç, B Ayazgok, A Balkan Pharmaceutical Chemistry Journal 53, 322-328, 2019 | 5 | 2019 |
Neurotoxic effects of bisphenol A on SH-SY5Y neuroblastoma cells via nitric oxide B AYAZGÖK, Z Tuylu Kucukkilinc Marmara Pharmaceutical Journal 23 (3), 2019 | 4 | 2019 |