Mark Pinese

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Andrew BiankinRegius Professor of Surgery, University of GlasgowVerified email at glasgow.ac.uk
Mark James CowleyComputational Biology Group leader, Children's Cancer Institute and Associate Professor at UNSWVerified email at ccia.org.au
David K. ChangProfessor of Surgical Oncology, University of GlasgowVerified email at glasgow.ac.uk
James KenchLocal Pathology Director, Royal Prince Alfred Hospital and Clinical Professor, University of SydneyVerified email at health.nsw.gov.au
Nicola WaddellQIMR Berghofer Medical Research InstituteVerified email at qimrberghofer.edu.au
Anthony GillProfessor of Surgical Pathology, University of SydneyVerified email at med.usyd.edu.au
Adnan NagrialUniversity of SydneyVerified email at health.nsw.gov.au
Sandra O'TooleClinical Professor Sydney University and Staff Specialist Tissue Pathology Royal Prince Alfred HospitalVerified email at garvan.org.au
john v pearsonQIMR Berghofer MRIVerified email at qimrberghofer.edu.au
Velimir GayevskiyRancho BiosciencesVerified email at vel.bio
Marie WongChildren's Cancer InstituteVerified email at ccia.org.au
Marcel E. DingerUniversity of SydneyVerified email at marceldinger.net
Prof. Sean M. GrimmondCollaborative Centre for Genomic Cancer Medicine, University of MelbourneVerified email at unimelb.edu.au
Chelsea MayohChildren's Cancer Institute, Sydney, AustraliaVerified email at ccia.org.au
Venessa ChinGarvan Institute of Medical ResearchVerified email at garvan.org.au
lorraine chantrillSenior Staff Specialist and Director Medical Oncology; Illawarra Shoalhaven Local Health DistrictVerified email at health.nsw.gov.au
David S ZieglerSydney Children's HospitalVerified email at unsw.edu.au
Nigel B JamiesonProfessor of Surgery and Consultant HPB Surgeon, Glasgow UniversityVerified email at glasgow.ac.uk
Angela ChouRoyal North Shore Hospital and Kolling Institute of Medical ResearchVerified email at sydney.edu.au
Roger DalyDept of Biochemistry and Molecular Biology, Monash UniversityVerified email at monash.edu

Mark Pinese

Children's Cancer Institute

Verified email at ccia.org.au

Genomics Cancer Biostatistics Bioinformatics


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Genomic analyses identify molecular subtypes of pancreatic cancer P Bailey, DK Chang, K Nones, AL Johns, AM Patch, MC Gingras, ... Nature 531 (7592), 47-52, 2016	3474	2016
Whole genomes redefine the mutational landscape of pancreatic cancer N Waddell, M Pajic, AM Patch, DK Chang, KS Kassahn, P Bailey, ... Nature 518 (7540), 495-501, 2015	2792	2015
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes AV Biankin, N Waddell, KS Kassahn, MC Gingras, LB Muthuswamy, ... Nature 491 (7424), 399-405, 2012	2272	2012
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020	1978*	2020
Whole-genome landscape of pancreatic neuroendocrine tumours A Scarpa, DK Chang, K Nones, V Corbo, AM Patch, P Bailey, RT Lawlor, ... Nature 543 (7643), 65-71, 2017	935	2017
PINA v2. 0: mining interactome modules MJ Cowley, M Pinese, KS Kassahn, N Waddell, JV Pearson, ... Nucleic acids research 40 (D1), D862-D865, 2012	393	2012
Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer M Wong, C Mayoh, LMS Lau, DA Khuong-Quang, M Pinese, A Kumar, ... Nature medicine 26 (11), 1742-1753, 2020	292	2020
Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy BW Miller, JP Morton, M Pinese, G Saturno, NB Jamieson, E McGhee, ... EMBO molecular medicine 7 (8), 1063-1076, 2015	290	2015
Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis C Vennin, VT Chin, SC Warren, MC Lucas, D Herrmann, A Magenau, ... Science translational medicine 9 (384), eaai8504, 2017	259	2017
Genome‐wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT‐ROBO, ITGA2 and MET signaling K Nones, N Waddell, S Song, AM Patch, D Miller, A Johns, J Wu, ... International journal of cancer 135 (5), 1110-1118, 2014	259	2014
CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan C Vennin, P Mélénec, R Rouet, M Nobis, AS Cazet, KJ Murphy, ... Nature communications 10 (1), 3637, 2019	236	2019
Hypermutation in pancreatic cancer JL Humphris, AM Patch, K Nones, PJ Bailey, AL Johns, S McKay, ... Gastroenterology 152 (1), 68-74. e2, 2017	224	2017
Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells F Hochgräfe, L Zhang, SA O'Toole, BC Browne, M Pinese, A Porta Cubas, ... Cancer research 70 (22), 9391-9401, 2010	213	2010
Histomolecular phenotypes and outcome in adenocarcinoma of the ampulla of vater DK Chang, NB Jamieson, AL Johns, CJ Scarlett, M Pajic, A Chou, ... Journal of clinical oncology 31 (10), 1348-1356, 2013	195	2013
Clinical and molecular characterization of HER2amplified-pancreatic cancer A Chou, N Waddell, MJ Cowley, AJ Gill, DK Chang, AM Patch, K Nones, ... Genome medicine 5, 1-11, 2013	146	2013
Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer A Chou, D Froio, AM Nagrial, A Parkin, KJ Murphy, VT Chin, D Wohl, ... Gut 67 (12), 2142-2155, 2018	130	2018
Targeting DNA damage response and replication stress in pancreatic cancer SB Dreyer, R Upstill-Goddard, V Paulus-Hock, C Paris, EM Lampraki, ... Gastroenterology 160 (1), 362-377. e13, 2021	122	2021
Identification of functional networks of estrogen-and c-Myc-responsive genes and their relationship to response to tamoxifen therapy in breast cancer EA Musgrove, CM Sergio, S Loi, CK Inman, LR Anderson, MC Alles, ... PloS one 3 (8), e2987, 2008	120	2008
Brief report: potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma DS Ziegler, M Wong, C Mayoh, A Kumar, M Tsoli, E Mould, V Tyrrell, ... British Journal of Cancer 119 (6), 693-696, 2018	119	2018
qpure: A tool to estimate tumor cellularity from genome-wide single-nucleotide polymorphism profiles S Song, K Nones, D Miller, I Harliwong, KS Kassahn, M Pinese, M Pajic, ... Public Library of Science 7 (9), e45835, 2012	116	2012

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