The structure and catalytic mechanism of a poly (ADP-ribose) glycohydrolase D Slade, MS Dunstan, E Barkauskaite, R Weston, P Lafite, N Dixon, ... Nature 477 (7366), 616-620, 2011 | 434 | 2011 |
Visualization of poly(ADP-ribose) bound to PARG reveals inherent balance between exo- and endo-glycohydrolase activities E Barkauskaite, A Brassington, ES Tan, J Warwicker, MS Dunstan, ... Nature communications 4 (1), 2164, 2013 | 164 | 2013 |
The structure of Mycobacterium tuberculosis CYP125 KJ McLean, P Lafite, C Levy, MR Cheesman, N Mast, IA Pikuleva, D Leys, ... Journal of Biological Chemistry 284 (51), 35524-35533, 2009 | 146 | 2009 |
Structural basis of kynurenine 3-monooxygenase inhibition M Amaral, C Levy, DJ Heyes, P Lafite, TF Outeiro, F Giorgini, D Leys, ... Nature 496 (7445), 382-385, 2013 | 143 | 2013 |
Structural and biochemical characterization of Mycobacterium tuberculosis CYP142: evidence for multiple cholesterol 27-hydroxylase activities in a human pathogen MD Driscoll, KJ McLean, C Levy, N Mast, IA Pikuleva, P Lafite, SEJ Rigby, ... Journal of biological chemistry 285 (49), 38270-38282, 2010 | 133 | 2010 |
Structure and mechanism of a canonical poly (ADP-ribose) glycohydrolase MS Dunstan, E Barkauskaite, P Lafite, CE Knezevic, A Brassington, ... Nature communications 3 (1), 878, 2012 | 98 | 2012 |
Unusual regioselectivity and active site topology of human cytochrome P450 2J2 P Lafite, F André, DC Zeldin, PM Dansette, D Mansuy Biochemistry 46 (36), 10237-10247, 2007 | 69 | 2007 |
Rare and unusual glycosylation of peptides and proteins P Lafite, R Daniellou Natural product reports 29 (7), 729-738, 2012 | 66 | 2012 |
New development in in-capillary electrophoresis techniques for kinetic and inhibition study of enzymes H Nehme, R Nehme, P Lafite, S Routier, P Morin Analytica chimica acta 722, 127-135, 2012 | 62 | 2012 |
Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2 P Lafite, S Dijols, D Buisson, AC Macherey, DC Zeldin, PM Dansette, ... Bioorganic & medicinal chemistry letters 16 (10), 2777-2780, 2006 | 60 | 2006 |
Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2 P Lafite, S Dijols, DC Zeldin, PM Dansette, D Mansuy Archives of biochemistry and biophysics 464 (2), 155-168, 2007 | 56 | 2007 |
Enzymatic synthesis of glycosides: from natural O-and N-glycosides to rare C-and S-glycosides J Ati, P Lafite, R Daniellou Beilstein journal of organic chemistry 13 (1), 1857-1865, 2017 | 54 | 2017 |
Synthesis of High‐Mannose Oligosaccharide Analogues through Click Chemistry: True Functional Mimics of Their Natural Counterparts Against Lectins? M François‐Heude, A Méndez‐Ardoy, V Cendret, P Lafite, R Daniellou, ... Chemistry–A European Journal 21 (5), 1978-1991, 2015 | 40 | 2015 |
Human protein kinase inhibitor screening by capillary electrophoresis using transverse diffusion of laminar flow profiles for reactant mixing H Nehmé, R Nehmé, P Lafite, S Routier, P Morin Journal of Chromatography A 1314, 298-305, 2013 | 38 | 2013 |
Rabbit aorta converts 15-HPETE to trihydroxyeicosatrienoic acids: potential role of cytochrome P450 SL Pfister, N Spitzbarth, DC Zeldin, P Lafite, D Mansuy, WB Campbell Archives of biochemistry and biophysics 420 (1), 142-152, 2003 | 37 | 2003 |
Structure-based mechanism of CMP-2-keto-3-deoxymanno-octulonic acid synthetase DJ Heyes, C Levy, P Lafite, IS Roberts, M Goldrick, AV Stachulski, ... Journal of Biological Chemistry 284 (51), 35514-35523, 2009 | 35 | 2009 |
Biochemical Characterization of the α-l-Rhamnosidase DtRha from Dictyoglomus thermophilum: Application to the Selective Derhamnosylation of Natural … L Guillotin, H Kim, Y Traore, P Moreau, P Lafite, V Coquoin, S Nuccio, ... ACS omega 4 (1), 1916-1922, 2019 | 31 | 2019 |
An internal reaction chamber in dimethylglycine oxidase provides efficient protection from exposure to toxic formaldehyde T Tralau, P Lafite, C Levy, JP Combe, NS Scrutton, D Leys Journal of Biological Chemistry 284 (26), 17826-17834, 2009 | 29 | 2009 |
Parallel pathways and free‐energy landscapes for enzymatic hydride transfer probed by hydrostatic pressure CR Pudney, T McGrory, P Lafite, J Pang, S Hay, D Leys, MJ Sutcliffe, ... ChemBioChem 10 (8), 1379-1384, 2009 | 27 | 2009 |
Unraveling the Substrate Recognition Mechanism and Specificity of the Unusual Glycosyl Hydrolase Family 29 BT2192 from Bacteroides thetaiotaomicron L Guillotin, P Lafite, R Daniellou Biochemistry 53 (9), 1447-1455, 2014 | 26 | 2014 |