Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses AM Sandmair, S Loimas, P Puranen, A Immonen, M Kossila, M Puranen, ... Human gene therapy 11 (16), 2197-2205, 2000 | 368 | 2000 |
β-Galactosidase Gene Transfer to Human Malignant Glioma In Vivo Using Replication-Deficient Retroviruses and Adenoviruses AM Puumalainen, M Vapalahti, RS Agrawal, M Kossila, J Laukkanen, ... Human gene therapy 9 (12), 1769-1774, 1998 | 233 | 1998 |
Magnetic tagging increases delivery of circulating progenitors in vascular injury PG Kyrtatos, P Lehtolainen, M Junemann-Ramirez, A Garcia-Prieto, ... JACC: Cardiovascular Interventions 2 (8), 794-802, 2009 | 186 | 2009 |
Gene transfer into the carotid artery using an adventitial collar: comparison of the effectiveness of the plasmid–liposome complexes, retroviruses, pseudotyped retroviruses … M Laitinen, T Pakkanen, E Donetti, R Baetta, J Luoma, P Lehtolainen, ... Human gene therapy 8 (14), 1645-1650, 1997 | 156 | 1997 |
Baculoviruses exhibit restricted cell type specificity in rat brain: a comparison of baculovirus-and adenovirus-mediated intracerebral gene transfer in vivo P Lehtolainen, K Tyynelä, J Kannasto, KJ Airenne, S Ylä-Herttuala Gene therapy 9 (24), 1693-1699, 2002 | 137 | 2002 |
Enhanced gene delivery by avidin-displaying baculovirus JK Räty, KJ Airenne, AT Marttila, V Marjomäki, VP Hytönen, P Lehtolainen, ... Molecular therapy 9 (2), 282-291, 2004 | 135 | 2004 |
Baculovirus capsid display: a novel tool for transduction imaging SP Kukkonen, KJ Airenne, V Marjomäki, OH Laitinen, P Lehtolainen, ... Molecular Therapy 8 (5), 853-862, 2003 | 131 | 2003 |
Overexpression of PHGPx inhibits hydroperoxide-induced oxidation, NFκB activation and apoptosis and affects oxLDL-mediated proliferation of rabbit aortic smooth muscle cells R Brigelius-Flohé, S Maurer, K Lötzer, GF Böl, H Kallionpää, ... Atherosclerosis 152 (2), 307-316, 2000 | 124 | 2000 |
Chondroitin sulphate‐modified neuropilin 1 is expressed in human tumour cells and modulates 3D invasion in the U87MG human glioblastoma cell line through a p130Cas‐mediated pathway P Frankel, C Pellet‐Many, P Lehtolainen, GM D'Abaco, ML Tickner, ... EMBO reports 9 (10), 983-989, 2008 | 92 | 2008 |
Adenovirus-mediated gene transfer of a secreted form of human macrophage scavenger receptor inhibits modified low-density lipoprotein degradation and foam-cell formation in … J Laukkanen, P Lehtolainen, PJ Gough, DR Greaves, S Gordon, ... Circulation 101 (10), 1091-1096, 2000 | 62 | 2000 |
Rabbit extracellular superoxide dismutase: expression and effect on LDL oxidation MO Laukkanen, P Lehtolainen, P Turunen, S Aittomäki, P Oikari, ... Gene 254 (1-2), 173-179, 2000 | 54 | 2000 |
Enhanced plasma cholesterol lowering effect of retrovirus-mediated LDL receptor gene transfer to WHHL rabbit liver after improved surgical technique and stimulation of … TM Pakkanen, M Laitinen, M Hippeläinen, H Kallionpää, P Lehtolainen, ... Gene therapy 6 (1), 34-41, 1999 | 50 | 1999 |
Targeting of biotinylated compounds to its target tissue using a low-density lipoprotein receptor–avidin fusion protein P Lehtolainen, T Wirth, AK Taskinen, P Lehenkari, O Leppänen, ... Gene therapy 10 (25), 2090-2097, 2003 | 41 | 2003 |
Cloning and characterization of Scavidin, a fusion protein for the targeted delivery of biotinylated molecules P Lehtolainen, A Taskinen, J Laukkanen, KJ Airenne, S Heino, ... Journal of Biological Chemistry 277 (10), 8545-8550, 2002 | 32 | 2002 |
Transfection of oocytes and other types of ovarian cells in rabbits after direct injection into uterine arteries of adenoviruses and plasmid/liposomes A Laurema, A Heikkilä, L Keski-Nisula, T Heikura, P Lehtolainen, ... Gene therapy 10 (7), 580-584, 2003 | 30 | 2003 |
Targeted delivery via avidin fusion protein: intracellular fate of biotinylated doxorubicin derivative and cellular uptake kinetics and biodistribution of biotinylated liposomes SK Soininen, P Lehtolainen-Dalkilic, T Karppinen, T Puustinen, ... European journal of pharmaceutical sciences 47 (5), 848-856, 2012 | 24 | 2012 |
Pathogenesis of atherosclerosis S Ylä-Herttuala, J Luoma, H Kallionpää, M Laukkanen, P Lehtolainen, ... Maturitas 23, S47-S49, 1996 | 23 | 1996 |
Avidin fusion protein-expressing lentiviral vector for targeted drug delivery HP Lesch, JT Pikkarainen, MU Kaikkonen, M Taavitsainen, ... Human gene therapy 20 (8), 871-882, 2009 | 19 | 2009 |
A stable bis-allyloxycarbonyl biotin aldehyde derivative for biotinylation via reductive alkylation: application to the synthesis of a biotinylated doxorubicin derivative B Allart, P Lehtolainen, S Yla-Herttuala, JF Martin, DL Selwood Bioconjugate chemistry 14 (1), 187-194, 2003 | 19 | 2003 |
Improvement in adenoviral gene transfer efficiency after preincubation at+ 37 C in vitro and in vivo M Kossila, S Jauhiainen, MO Laukkanen, P Lehtolainen, M Jääskeläinen, ... Molecular therapy 5 (1), 87-93, 2002 | 19 | 2002 |