| Functional consequences of caspase activation in cardiac myocytes C Communal, M Sumandea, P de Tombe, J Narula, RJ Solaro, RJ Hajjar Proceedings of the National Academy of Sciences 99 (9), 6252-6256, 2002 | 510 | 2002 |
| Titin isoform switch in ischemic human heart disease C Neagoe, M Kulke, F del Monte, JK Gwathmey, PP de Tombe, RJ Hajjar, ... Circulation 106 (11), 1333-1341, 2002 | 471 | 2002 |
| Approximate model of cooperative activation and crossbridge cycling in cardiac muscle using ordinary differential equations JJ Rice, F Wang, DM Bers, PP De Tombe Biophysical journal 95 (5), 2368-2390, 2008 | 401 | 2008 |
| Myofilament length dependent activation PP de Tombe, RD Mateja, K Tachampa, YA Mou, GP Farman, TC Irving Journal of molecular and cellular cardiology 48 (5), 851-858, 2010 | 319 | 2010 |
| Identification of a functionally critical protein kinase C phosphorylation residue of cardiac troponin T MP Sumandea, WG Pyle, T Kobayashi, PP de Tombe, RJ Solaro Journal of Biological Chemistry 278 (37), 35135-35144, 2003 | 227 | 2003 |
| Force and velocity of sarcomere shortening in trabeculae from rat heart. Effects of temperature. PP de Tombe, HE Ter Keurs Circulation research 66 (5), 1239-1254, 1990 | 195 | 1990 |
| Ventricular stroke work and efficiency both remain nearly optimal despite altered vascular loading PP De Tombe, S Jones, D Burkhoff, WC Hunter, DA Kass American Journal of Physiology-Heart and Circulatory Physiology 264 (6 …, 1993 | 190 | 1993 |
| Augmented protein kinase C-α–induced myofilament protein phosphorylation contributes to myofilament dysfunction in experimental congestive heart failure RJ Belin, MP Sumandea, EJ Allen, K Schoenfelt, H Wang, RJ Solaro, ... Circulation research 101 (2), 195-204, 2007 | 188 | 2007 |
| Troponin I in the murine myocardium: influence on length‐dependent activation and interfilament spacing JP Konhilas, TC Irving, BM Wolska, EE Jweied, AF Martin, RJ Solaro, ... The Journal of physiology 547 (3), 951-961, 2003 | 180 | 2003 |
| Titin strain contributes to the Frank–Starling law of the heart by structural rearrangements of both thin-and thick-filament proteins Y Ait-Mou, K Hsu, GP Farman, M Kumar, ML Greaser, TC Irving, ... Proceedings of the National Academy of Sciences 113 (8), 2306-2311, 2016 | 179 | 2016 |
| Myofilament lattice spacing as a function of sarcomere length in isolated rat myocardium TC Irving, J Konhilas, D Perry, R Fischetti, PP De Tombe American Journal of Physiology-Heart and Circulatory Physiology 279 (5 …, 2000 | 177 | 2000 |
| Myofilament calcium sensitivity in skinned rat cardiac trabeculae: role of interfilament spacing JP Konhilas, TC Irving, PP de Tombe Circulation research 90 (1), 59-65, 2002 | 169 | 2002 |
| Protein kinase A does not alter economy of force maintenance in skinned rat cardiac trabeculae PP de Tombe, GJM Stienen Circulation research 76 (5), 734-741, 1995 | 169 | 1995 |
| Cooperative activation in cardiac muscle: impact of sarcomere length DP Dobesh, JP Konhilas, PP de Tombe American Journal of Physiology-Heart and Circulatory Physiology 282 (3 …, 2002 | 163 | 2002 |
| Altered contractile function in heart failure PP De Tombe Cardiovascular research 37 (2), 367-380, 1998 | 161 | 1998 |
| An internal viscous element limits unloaded velocity of sarcomere shortening in rat myocardium. PP de Tombe, HE Ter Keurs The Journal of Physiology 454 (1), 619-642, 1992 | 155 | 1992 |
| Impact of β-myosin heavy chain isoform expression on cross-bridge cycling kinetics VLM Rundell, V Manaves, AF Martin, PP de Tombe American Journal of Physiology-Heart and Circulatory Physiology 288 (2 …, 2005 | 154 | 2005 |
| A model of propagating calcium-induced calcium release mediated by calcium diffusion. PH Backx, PP De Tombe, JH Van Deen, BJ Mulder, HE Ter Keurs The Journal of general physiology 93 (5), 963-977, 1989 | 151 | 1989 |
| The troponin C G159D mutation blunts myofilament desensitization induced by troponin I Ser23/24 phosphorylation BJ Biesiadecki, T Kobayashi, JS Walker, R John Solaro, PP De Tombe Circulation research 100 (10), 1486-1493, 2007 | 147 | 2007 |
| Frank-Starling law of the heart and the cellular mechanisms of length-dependent activation JP Konhilas, TC Irving, PP de Tombe Pflügers Archiv 445, 305-310, 2002 | 144 | 2002 |
