| A non-canonical vitamin K cycle is a potent ferroptosis suppressor E Mishima, J Ito, Z Wu, T Nakamura, A Wahida, S Doll, W Tonnus, ... Nature 608 (7924), 778-783, 2022 | 270 | 2022 |
| Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease K Kikuchi, D Saigusa, Y Kanemitsu, Y Matsumoto, P Thanai, N Suzuki, ... Nature communications 10 (1), 1835, 2019 | 207 | 2019 |
| Alteration of the intestinal environment by lubiprostone is associated with amelioration of adenine-induced CKD E Mishima, S Fukuda, H Shima, A Hirayama, Y Akiyama, Y Takeuchi, ... Journal of the American Society of Nephrology 26 (8), 1787-1794, 2015 | 206 | 2015 |
| Evaluation of the impact of gut microbiota on uremic solute accumulation by a CE-TOFMS–based metabolomics approach E Mishima, S Fukuda, C Mukawa, A Yuri, Y Kanemitsu, Y Matsumoto, ... Kidney International 92 (3), 634-645, 2017 | 205 | 2017 |
| Metabolic alterations by indoxyl sulfate in skeletal muscle induce uremic sarcopenia in chronic kidney disease E Sato, T Mori, E Mishima, A Suzuki, S Sugawara, N Kurasawa, ... Scientific reports 6 (1), 36618, 2016 | 165 | 2016 |
| Metabolomic profiling of uremic solutes in CKD patients T Toyohara, Y Akiyama, T Suzuki, Y Takeuchi, E Mishima, M Tanemoto, ... Hypertension research 33 (9), 944-952, 2010 | 158 | 2010 |
| SLCO4C1 transporter eliminates uremic toxins and attenuates hypertension and renal inflammation T Toyohara, T Suzuki, R Morimoto, Y Akiyama, T Souma, HO Shiwaku, ... Journal of the American Society of Nephrology 20 (12), 2546-2555, 2009 | 140 | 2009 |
| Drugs repurposed as antiferroptosis agents suppress organ damage, including AKI, by functioning as lipid peroxyl radical scavengers E Mishima, E Sato, J Ito, K Yamada, C Suzuki, Y Oikawa, T Matsuhashi, ... Journal of the American Society of Nephrology 31 (2), 280-296, 2020 | 112 | 2020 |
| Sorafenib fails to trigger ferroptosis across a wide range of cancer cell lines J Zheng, M Sato, E Mishima, H Sato, B Proneth, M Conrad Cell death & disease 12 (7), 698, 2021 | 108 | 2021 |
| Uric acid elevation by favipiravir, an antiviral drug E Mishima, N Anzai, M Miyazaki, T Abe The Tohoku journal of experimental medicine 251 (2), 87-90, 2020 | 104 | 2020 |
| Conformational change in transfer RNA is an early indicator of acute cellular damage E Mishima, C Inoue, D Saigusa, R Inoue, K Ito, Y Suzuki, D Jinno, ... Journal of the American Society of Nephrology 25 (10), 2316-2326, 2014 | 104 | 2014 |
| Canagliflozin reduces plasma uremic toxins and alters the intestinal microbiota composition in a chronic kidney disease mouse model E Mishima, S Fukuda, Y Kanemitsu, D Saigusa, C Mukawa, K Asaji, ... American Journal of Physiology-Renal Physiology 315 (4), F824-F833, 2018 | 97 | 2018 |
| Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocyte damage T Suzuki, H Yamaguchi, M Kikusato, O Hashizume, S Nagatoishi, ... Journal of the American Society of Nephrology 27 (7), 1925-1932, 2016 | 86 | 2016 |
| Mutation of the Mg2+ transporter SLC41A1 results in a nephronophthisis-like phenotype TW Hurd, EA Otto, E Mishima, HY Gee, H Inoue, M Inazu, H Yamada, ... Journal of the American Society of Nephrology 24 (6), 967-977, 2013 | 81 | 2013 |
| Impact of the oral adsorbent AST-120 on organ-specific accumulation of uremic toxins: LC-MS/MS and MS imaging techniques E Sato, D Saigusa, E Mishima, T Uchida, D Miura, T Morikawa-Ichinose, ... Toxins 10 (1), 19, 2017 | 79 | 2017 |
| Immuno-northern blotting: detection of RNA modifications by using antibodies against modified nucleosides E Mishima, D Jinno, Y Akiyama, K Itoh, S Nankumo, H Shima, K Kikuchi, ... PloS one 10 (11), e0143756, 2015 | 78 | 2015 |
| Phase separation of FSP1 promotes ferroptosis T Nakamura, C Hipp, A Santos Dias Mourão, J Borggräfe, M Aldrovandi, ... Nature 619 (7969), 371-377, 2023 | 65 | 2023 |
| Stress‐induced tRNA cleavage and tiRNA generation in rat neuronal PC12 cells A Elkordy, E Mishima, K Niizuma, Y Akiyama, M Fujimura, T Tominaga, ... Journal of neurochemistry 146 (5), 560-569, 2018 | 61 | 2018 |
| Mitochonic acid 5 (MA-5) facilitates ATP synthase oligomerization and cell survival in various mitochondrial diseases T Matsuhashi, T Sato, S Kanno, T Suzuki, A Matsuo, Y Oba, M Kikusato, ... EBioMedicine 20, 27-38, 2017 | 61 | 2017 |
| The stress specific impact of ALKBH1 on tRNA cleavage and tiRNA generation S Rashad, X Han, K Sato, E Mishima, T Abe, T Tominaga, K Niizuma RNA biology 17 (8), 1092-1103, 2020 | 54 | 2020 |
