| Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway SC Wei, L Fattet, JH Tsai, Y Guo, VH Pai, HE Majeski, AC Chen, RL Sah, ... Nature cell biology 17 (5), 678-688, 2015 | 878 | 2015 |
| Molecular pathways: linking tumor microenvironment to epithelial–mesenchymal transition in metastasis HY Jung, L Fattet, J Yang Clinical Cancer Research 21 (5), 962-968, 2015 | 325 | 2015 |
| RNA helicases DDX5 and DDX17 dynamically orchestrate transcription, miRNA, and splicing programs in cell differentiation E Dardenne, MP Espinoza, L Fattet, S Germann, MP Lambert, H Neil, ... Cell reports 7 (6), 1900-1913, 2014 | 206 | 2014 |
| Matrix rigidity controls epithelial-mesenchymal plasticity and tumor metastasis via a mechanoresponsive EPHA2/LYN complex L Fattet, HY Jung, MW Matsumoto, BE Aubol, A Kumar, JA Adams, ... Developmental cell 54 (3), 302-316. e7, 2020 | 153 | 2020 |
| Dynamically stiffened matrix promotes malignant transformation of mammary epithelial cells via collective mechanical signaling MG Ondeck, A Kumar, JK Placone, CM Plunkett, BF Matte, KC Wong, ... Proceedings of the National Academy of Sciences 116 (9), 3502-3507, 2019 | 139 | 2019 |
| Apical–basal polarity inhibits epithelial–mesenchymal transition and tumour metastasis by PAR-complex-mediated SNAI1 degradation HY Jung, L Fattet, JH Tsai, T Kajimoto, Q Chang, AC Newton, J Yang Nature cell biology 21 (3), 359-371, 2019 | 129 | 2019 |
| Release of SR proteins from CLK1 by SRPK1: a symbiotic kinase system for phosphorylation control of pre-mRNA splicing BE Aubol, G Wu, MM Keshwani, M Movassat, L Fattet, KJ Hertel, XD Fu, ... Molecular cell 63 (2), 218-228, 2016 | 92 | 2016 |
| Antagonistic regulation of EMT by TIF1γ and Smad4 in mammary epithelial cells C Hesling, L Fattet, G Teyre, D Jury, P Gonzalo, J Lopez, C Vanbelle, ... EMBO reports 12 (7), 665-672, 2011 | 84 | 2011 |
| Biomaterials to model and measure epithelial cancers P Beri, BF Matte, L Fattet, D Kim, J Yang, AJ Engler Nature Reviews Materials 3 (11), 418-430, 2018 | 63 | 2018 |
| The disintegrin and metalloprotease ADAM12 is associated with TGF-β-induced epithelial to mesenchymal transition M Ruff, A Leyme, F Le Cann, D Bonnier, J Le Seyec, F Chesnel, L Fattet, ... PLoS One 10 (9), e0139179, 2015 | 62 | 2015 |
| TIF1γ interferes with TGFβ1/SMAD4 signaling to promote poor outcome in operable breast cancer patients L Kassem, M Deygas, L Fattet, J Lopez, T Goulvent, E Lavergne, ... BMC cancer 15, 1-13, 2015 | 46 | 2015 |
| Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function MM Keshwani, BE Aubol, L Fattet, CT Ma, J Qiu, PA Jennings, XD Fu, ... Biochemical Journal 466 (2), 311-322, 2015 | 45 | 2015 |
| The forces behind EMT and tumor metastasis SC Wei, L Fattet, J Yang Cell Cycle 14 (15), 2387-2388, 2015 | 38 | 2015 |
| TIF1γ requires sumoylation to exert its repressive activity on TGFβ signaling L Fattet, AS Ay, B Bonneau, L Jallades, I Mikaelian, I Treilleux, G Gillet, ... Journal of cell science 126 (16), 3713-3723, 2013 | 33 | 2013 |
| Dynamic regulation of Tgf-B signaling by Tif1γ: a computational approach G Andrieux, L Fattet, M Le Borgne, R Rimokh, N Théret PloS one 7 (3), e33761, 2012 | 33 | 2012 |
| Tif1γ is essential for the terminal differentiation of mammary alveolar epithelial cells and for lactation through SMAD4 inhibition C Hesling, J Lopez, L Fattet, P Gonzalo, I Treilleux, D Blanchard, ... Development 140 (1), 167-175, 2013 | 31 | 2013 |
| Mobilization of a splicing factor through a nuclear kinase–kinase complex BE Aubol, MM Keshwani, L Fattet, JA Adams Biochemical Journal 475 (3), 677-690, 2018 | 28 | 2018 |
| Molecular interactions connecting the function of the serine-arginine–rich protein SRSF1 to protein phosphatase 1 BE Aubol, P Serrano, L Fattet, K Wüthrich, JA Adams Journal of Biological Chemistry 293 (43), 16751-16760, 2018 | 24 | 2018 |
| Redirecting SR protein nuclear trafficking through an allosteric platform BE Aubol, KL Hailey, L Fattet, PA Jennings, JA Adams Journal of molecular biology 429 (14), 2178-2191, 2017 | 23 | 2017 |
| Nuclear protein kinase CLK1 uses a non-traditional docking mechanism to select physiological substrates MM Keshwani, KL Hailey, BE Aubol, L Fattet, ML McGlone, PA Jennings, ... Biochemical Journal 472 (3), 329-338, 2015 | 22 | 2015 |
Joseph AdamsProfessor of PharmacologyVerified email at ucsd.edu
