Design, synthesis and pharmacological profile of novel dopamine D2 receptor ligands R Menegatti, AC Cunha, VF Ferreira, EFR Perreira, A El-Nabawi, ... Bioorganic & medicinal chemistry 11 (22), 4807-4813, 2003 | 111 | 2003 |
Piperazine derivatives with central pharmacological activity used as therapeutic tools AF Brito, LKS Moreira, R Menegatti, EA Costa Fundamental & clinical pharmacology 33 (1), 13-24, 2019 | 89 | 2019 |
Searching for multi-target antipsychotics: discovery of orally active heterocyclic N-phenylpiperazine ligands of D2-like and 5-HT1A receptors G Neves, R Menegatti, CB Antonio, LR Grazziottin, RO Vieira, SMK Rates, ... Bioorganic & medicinal chemistry 18 (5), 1925-1935, 2010 | 76 | 2010 |
Heterocyclic compounds: pharmacology of pyrazole analogs from rational structural considerations RF Costa, LC Turones, KVN Cavalcante, IA Rosa Júnior, CH Xavier, ... Frontiers in Pharmacology 12, 666725, 2021 | 60 | 2021 |
Design, synthesis, and pharmacological evaluation of new neuroactive pyrazolo [3, 4-b] pyrrolo [3, 4-d] pyridine derivatives with in vivo hypnotic and analgesic profile R Menegatti, GMS Silva, G Zapata-Sudo, JM Raimundo, RT Sudo, ... Bioorganic & medicinal chemistry 14 (3), 632-640, 2006 | 54 | 2006 |
A importância da síntese de fármacos R MENEGATTI, CAM FRAGA, EJ BARREIRO Cadernos temáticos de química nova na escola 3, 16-22, 2001 | 51 | 2001 |
Involvement of the NO/cGMP/KATP pathway in the antinociceptive effect of the new pyrazole 5-(1-(3-fluorophenyl)-1H-pyrazol-4-yl)-2H-tetrazole (LQFM-021) IF Florentino, PM Galdino, LP De Oliveira, DPB Silva, F Pazini, ... Nitric Oxide 47, 17-24, 2015 | 48 | 2015 |
Dopaminergic profile of new heterocyclic N-phenylpiperazine derivatives G Neves, R Fenner, AP Heckler, AF Viana, L Tasso, R Menegatti, ... Brazilian journal of medical and biological research 36, 625-629, 2003 | 48 | 2003 |
Potential anti-inflammatory effect of LQFM-021 in carrageenan-induced inflammation: the role of nitric oxide IF Florentino, DPB Silva, DM Silva, CS Cardoso, ALE Moreira, CL Borges, ... Nitric Oxide 69, 35-44, 2017 | 43 | 2017 |
Anti-inflammatory and antinociceptive activities of LQFM002—a 4-nerolidylcatechol derivative EA Costa, RC Lino, MN Gomes, MVM Nascimento, IF Florentino, ... Life sciences 92 (3), 237-244, 2013 | 29 | 2013 |
Green chemistry–aspects for the Knoevenagel reaction R Menegatti Green chemistry-environmentally benign approaches, 2012 | 28 | 2012 |
A novel chalcone derivative, LQFM064, induces breast cancer cells death via p53, p21, KIT and PDGFRA BLS Cabral, ACG da Silva, RI de Avila, AP Cortez, RM Luzin, LM Liao, ... European Journal of Pharmaceutical Sciences 107, 1-15, 2017 | 27 | 2017 |
4-Nerolidylcatechol and its synthetic analogues: Antioxidant activity and toxicity evaluation CRM da Cunha, SAM Neto, CC da Silva, AP Cortez, ... European Journal of Medicinal Chemistry 62, 371-378, 2013 | 27 | 2013 |
Mechanisms involved in the antinociceptive and anti-inflammatory effects of a new triazole derivative: 5-[1-(4-fluorophenyl)-1H-1,2,3-triazol-4-yl]-1H-tetrazole … CS Cardoso, DPB Silva, DM Silva, IF Florentino, JO Fajemiroye, ... Inflammopharmacology 28, 877-892, 2020 | 26 | 2020 |
Synthesis, docking studies, pharmacological activity and toxicity of a novel Pyrazole derivative (LQFM 021)—Possible effects on phosphodiesterase DR Martins, F Pazini, V de Medeiros Alves, SS de Moura, LM Lião, ... Chemical and Pharmaceutical Bulletin 61 (5), 524-531, 2013 | 26 | 2013 |
Central pharmacological activity of a new piperazine derivative: 4-(1-Phenyl-1h-pyrazol-4-ylmethyl)-piperazine-1-carboxylic acid ethyl ester AF de Brito, JLR Martins, JO Fajemiroye, PM Galdino, TCM De Lima, ... Life sciences 90 (23-24), 910-916, 2012 | 26 | 2012 |
Tert-butyl 4-((1-phenyl-1H-pyrazol-4-yl) methyl) piperazine-1-carboxylate (LQFM104)–new piperazine derivative with antianxiety and antidepressant-like effects: putative role of … DM da Silva, G Sanz, BG Vaz, FS de Carvalho, LM Lião, DR de Oliveira, ... Biomedicine & Pharmacotherapy 103, 546-552, 2018 | 23 | 2018 |
The Newly Synthesized Pyrazole Derivative 5-(1-(3 Fluorophenyl)-1 H-Pyrazol-4-yl)-2 H-Tetrazole Reduces Blood Pressure of Spontaneously Hypertensive Rats via NO/cGMO Pathway NR Trindade, PR Lopes, LM Naves, JO Fajemiroye, PH Alves, NO Amaral, ... Frontiers in Physiology 9, 1073, 2018 | 22 | 2018 |
Design, synthesis and pharmacological evaluation of new anti-inflammatory compounds AF Cidade, PA Vasconcelos, DPB Silva, IF Florentino, GA Vasconcelos, ... European journal of pharmacology 791, 195-204, 2016 | 22 | 2016 |
Antileishmanial activity of the chalcone derivative LQFM064 associated with reduced fluidity in the parasite membrane as assessed by EPR spectroscopy L Alonso, R Menegatti, RS Gomes, ML Dorta, RM Luzin, LM Liao, ... European Journal of Pharmaceutical Sciences 151, 105407, 2020 | 21 | 2020 |