“Perfect” designer chromosome V and behavior of a ring derivative ZX Xie, BZ Li, LA Mitchell, Y Wu, X Qi, Z Jin, B Jia, X Wang, BX Zeng, ... Science 355 (6329), eaaf4704, 2017 | 298 | 2017 |
Bug mapping and fitness testing of chemically synthesized chromosome X Y Wu, BZ Li, M Zhao, LA Mitchell, ZX Xie, QH Lin, X Wang, WH Xiao, ... Science 355 (6329), eaaf4706, 2017 | 272 | 2017 |
Engineering the ribosomal DNA in a megabase synthetic chromosome W Zhang, G Zhao, Z Luo, Y Lin, L Wang, Y Guo, A Wang, S Jiang, Q Jiang, ... Science 355 (6329), eaaf3981, 2017 | 248 | 2017 |
Precise control of SCRaMbLE in synthetic haploid and diploid yeast B Jia, Y Wu, BZ Li, LA Mitchell, H Liu, S Pan, J Wang, HR Zhang, N Jia, ... Nature communications 9 (1), 1933, 2018 | 170 | 2018 |
3D organization of synthetic and scrambled chromosomes G Mercy, J Mozziconacci, VF Scolari, K Yang, G Zhao, A Thierry, Y Luo, ... Science 355 (6329), eaaf4597, 2017 | 157 | 2017 |
In vitro DNA SCRaMbLE Y Wu, RY Zhu, LA Mitchell, L Ma, R Liu, M Zhao, B Jia, H Xu, YX Li, ... Nature communications 9 (1), 1935, 2018 | 116 | 2018 |
Heterozygous diploid and interspecies SCRaMbLEing MJ Shen, Y Wu, K Yang, Y Li, H Xu, H Zhang, BZ Li, X Li, WH Xiao, ... Nature communications 9 (1), 1934, 2018 | 109 | 2018 |
SCRaMbLE generates evolved yeasts with increased alkali tolerance L Ma, Y Li, X Chen, M Ding, Y Wu, YJ Yuan Microbial Cell Factories 18, 1-11, 2019 | 61 | 2019 |
Rapid and Efficient CRISPR/Cas9-Based Mating-Type Switching of Saccharomyces cerevisiae ZX Xie, LA Mitchell, HM Liu, BZ Li, D Liu, N Agmon, Y Wu, X Li, X Zhou, ... G3: Genes, Genomes, Genetics 8 (1), 173-183, 2018 | 47 | 2018 |
Chromosome drives via CRISPR-Cas9 in yeast H Xu, M Han, S Zhou, BZ Li, Y Wu, YJ Yuan Nature communications 11 (1), 4344, 2020 | 35 | 2020 |
Design and chemical synthesis of eukaryotic chromosomes ZX Xie, D Liu, BZ Li, M Zhao, BX Zeng, Y Wu, Y Shen, T Lin, P Yang, J Dai, ... Chemical Society Reviews 46 (23), 7191-7207, 2017 | 34 | 2017 |
Loss of heterozygosity by SCRaMbLEing Y Li, Y Wu, L Ma, Z Guo, W Xiao, Y Yuan Science China Life Sciences 62, 381-393, 2019 | 32 | 2019 |
Dynamics of synthetic yeast chromosome evolution shaped by hierarchical chromatin organization S Zhou, Y Wu, Y Zhao, Z Zhang, L Jiang, L Liu, Y Zhang, J Tang, YJ Yuan National Science Review 10 (5), nwad073, 2023 | 26 | 2023 |
SCRaMbLEing of a synthetic yeast chromosome with clustered essential genes reveals synthetic lethal interactions P Wang, H Xu, H Li, H Chen, S Zhou, F Tian, BZ Li, X Bo, Y Wu, YJ Yuan ACS Synthetic Biology 9 (5), 1181-1189, 2020 | 24 | 2020 |
Robust orthogonal recombination system for versatile genomic elements rearrangement in yeast Saccharomyces Cerevisiae Q Lin, H Qi, Y Wu, Y Yuan Scientific reports 5 (1), 15249, 2015 | 19 | 2015 |
Directed genome evolution driven by structural rearrangement techniques S Zhou, Y Wu, ZX Xie, B Jia, YJ Yuan Chemical Society Reviews 50 (22), 12788-12807, 2021 | 17 | 2021 |
YLC-assembly: large DNA assembly via yeast life cycle B He, Y Ma, F Tian, GR Zhao, Y Wu, YJ Yuan Nucleic Acids Research 51 (15), 8283-8292, 2023 | 13 | 2023 |
Enhancement and mapping of tolerance to salt stress and 5-fluorocytosine in synthetic yeast strains via SCRaMbLE J Kang, J Li, Z Guo, S Zhou, S Su, W Xiao, Y Wu, Y Yuan Synthetic and Systems Biotechnology 7 (3), 869-877, 2022 | 10 | 2022 |
Convenient synthesis and delivery of a megabase-scale designer accessory chromosome empower biosynthetic capacity Y Ma, S Su, Z Fu, C Zhou, B Qiao, Y Wu, YJ Yuan Cell Research 34 (4), 309-322, 2024 | 8 | 2024 |
Direct transfer and consolidation of synthetic yeast chromosomes by abortive mating and chromosome elimination Z Guo, H Yin, L Ma, J Li, J Ma, Y Wu, Y Yuan ACS Synthetic Biology 11 (10), 3264-3272, 2022 | 7 | 2022 |