Dana-Farber Cancer Institute, Harvard Medical School
Verified email at DFCI.HARVARD.EDU
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Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis
B Duan, YZ Wang, T Yang, XP Chu, Y Yu, Y Huang, H Cao, J Hansen, ...
Journal of Neuroscience 31 (6), 2101-2112, 2011
Tissue acidosis induces neuronal necroptosis via ASIC1a channel independent of its ionic conduction
YZ Wang, JJ Wang, Y Huang, F Liu, WZ Zeng, Y Li, ZG Xiong, MX Zhu, ...
Elife 4, e05682, 2015
PI3-kinase/Akt pathway-regulated membrane insertion of acid-sensing ion channel 1a underlies BDNF-induced pain hypersensitivity
B Duan, DS Liu, Y Huang, WZ Zeng, X Wang, H Yu, MX Zhu, ZY Chen, ...
Journal of Neuroscience 32 (18), 6351-6363, 2012
Drosophila TRPML forms PI (3, 5) P2-activated cation channels in both endolysosomes and plasma membrane
X Feng, Y Huang, Y Lu, J Xiong, CO Wong, P Yang, J Xia, D Chen, G Du, ...
Journal of Biological Chemistry 289 (7), 4262-4272, 2014
Imaging of Cell–Cell Communication in a Vertical Orientation Reveals High-Resolution Structure of Immunological Synapse and Novel PD-1 Dynamics
JH Jang, Y Huang, P Zheng, MC Jo, G Bertolet, MX Zhu, L Qin, D Liu
The Journal of Immunology 195 (3), 1320-1330, 2015
Critical roles of Gi/o proteins and phospholipase C-δ1 in the activation of receptor-operated TRPC4 channels
DP Thakur, J Tian, J Jeon, J Xiong, Y Huang, V Flockerzi, MX Zhu
Proceedings of the National Academy of Sciences 113 (4), 1092-1097, 2016
Intracellular ASIC1a regulates mitochondrial permeability transition-dependent neuronal death
YZ Wang, WZ Zeng, X Xiao, Y Huang, XL Song, Z Yu, D Tang, XP Dong, ...
Cell Death & Differentiation 20 (10), 1359-1369, 2013
Quiescent cancer cells resist T cell attack by forming an immunosuppressive niche
P Baldominos, A Barbera-Mourelle, O Barreiro, Y Huang, A Wight, ...
Cell 185 (10), 1694-1708. e19, 2022
Molecular mechanisms of functional natural killer deficiency in patients with partial DiGeorge syndrome
P Zheng, LM Noroski, IC Hanson, Y Chen, ME Lee, Y Huang, MX Zhu, ...
Journal of Allergy and Clinical Immunology 135 (5), 1293-1302, 2015
CAMK2/CaMKII activates MLKL in short-term starvation to facilitate autophagic flux
Q Zhan, J Jeon, Y Li, Y Huang, J Xiong, Q Wang, TL Xu, Y Li, FH Ji, G Du, ...
Autophagy, 1-19, 2021
PD-1 blocks lytic granule polarization with concomitant impairment of integrin outside-in signaling in the natural killer cell immunological synapse
Y Huang, Z Chen, JH Jang, MS Baig, G Bertolet, C Schroeder, S Huang, ...
Journal of Allergy and Clinical Immunology 142 (4), 1311-1321. e8, 2018
RIP3 Mediates Necroptotic Cell Death in Response to Acid Stimulation of ASIC1a
Y Huang, Q Hu, JL Huang, J Jeon, TL Xu, MX Zhu
Biophysical Journal 112 (3), 548a, 2017
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