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Yonatan Savir
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Year
The moderately efficient enzyme: evolutionary and physicochemical trends shaping enzyme parameters
A Bar-Even, E Noor, Y Savir, W Liebermeister, D Davidi, DS Tawfik, ...
Biochemistry 50 (21), 4402-4410, 2011
10562011
Cross-species analysis traces adaptation of Rubisco toward optimality in a low-dimensional landscape
Y Savir, E Noor, R Milo, T Tlusty
Proceedings of the National Academy of Sciences 107 (8), 3475-3480, 2010
3072010
Conformational proofreading: the impact of conformational changes on the specificity of molecular recognition
Y Savir, T Tlusty
PloS one 2 (5), e468, 2007
1572007
Galactose metabolic genes in yeast respond to a ratio of galactose and glucose
R Escalante-Chong, Y Savir, SM Carroll, JB Ingraham, J Wang, CJ Marx, ...
Proceedings of the National Academy of Sciences 112 (5), 1636-1641, 2015
1352015
Natural variation in preparation for nutrient depletion reveals a cost–benefit tradeoff
J Wang, E Atolia, B Hua, Y Savir, R Escalante-Chong, M Springer
PLoS biology 13 (1), e1002041, 2015
1332015
Discrete limbal epithelial stem cell populations mediate corneal homeostasis and wound healing
A Altshuler, A Amitai-Lange, N Tarazi, S Dey, L Strinkovsky, ...
Cell stem cell 28 (7), 1248-1261. e8, 2021
762021
RecA-mediated homology search as a nearly optimal signal detection system
Y Savir, T Tlusty
Molecular cell 40 (3), 388-396, 2010
672010
The ribosome as an optimal decoder: A lesson in molecular recognition
Y Savir, T Tlusty
Cell 153 (2), 471-479, 2013
622013
Decoupling transcription factor expression and activity enables dimmer switch gene regulation
C Ricci-Tam, I Ben-Zion, J Wang, J Palme, A Li, Y Savir, M Springer
Science 372 (6539), 292-295, 2021
282021
Machine learning approach for biopsy-based identification of eosinophilic esophagitis reveals importance of global features
T Czyzewski, N Daniel, M Rochman, JM Caldwell, GA Osswald, ...
IEEE open journal of engineering in medicine and biology 2, 218-223, 2021
272021
Nanoliter cell culture array with tunable chemical gradients
J Avesar, Y Blinder, H Aktin, A Szklanny, D Rosenfeld, Y Savir, ...
Analytical chemistry 90 (12), 7480-7488, 2018
242018
Balancing speed and accuracy of polyclonal T cell activation: a role for extracellular feedback
Y Savir, N Waysbort, YE Antebi, T Tlusty, N Friedman
BMC systems biology 6, 1-14, 2012
182012
Achieving global perfect homeostasis through transporter regulation
Y Savir, A Martynov, M Springer
PLoS computational biology 13 (4), e1005458, 2017
122017
Harnessing artificial intelligence to infer novel spatial biomarkers for the diagnosis of eosinophilic esophagitis
A Larey, E Aknin, N Daniel, GA Osswald, JM Caldwell, M Rochman, ...
Frontiers in Medicine 9, 950728, 2022
112022
Optimal design of a molecular recognizer: Molecular recognition as a Bayesian signal detection problem
Y Savir, T Tlusty
IEEE Journal of Selected Topics in Signal Processing 2 (3), 390-399, 2008
112008
A deep multi-label segmentation network for eosinophilic esophagitis whole slide biopsy diagnostics
N Daniel, A Larey, E Aknin, GA Osswald, JM Caldwell, M Rochman, ...
2022 44th Annual International Conference of the IEEE Engineering in …, 2022
102022
Single-cell analysis of the aged ovarian immune system reveals a shift towards adaptive immunity and attenuated cell function
TB Yaakov, T Wasserman, E Aknin, Y Savir
Elife 12, e74915, 2023
82023
Competitive inhibition can linearize dose-response and generate a linear rectifier
Y Savir, BP Tu, M Springer
Cell systems 1 (3), 238-245, 2015
72015
PECNet: A deep multi-label segmentation network for eosinophilic esophagitis biopsy diagnostics
N Daniel, A Larey, E Aknin, GA Osswald, JM Caldwell, M Rochman, ...
arXiv preprint arXiv:2103.02015, 2021
62021
Capturing limbal epithelial stem cell population dynamics, signature, and their niche
A Altshuler, A Amitai-Lange, N Tarazi, S Dey, L Strinkovsky, ...
BioRxiv, 2020.06. 30.179754, 2020
62020
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Articles 1–20