| The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis Q Huang, K Gumireddy, M Schrier, C Le Sage, R Nagel, S Nair, DA Egan, ... Nature cell biology 10 (2), 202-210, 2008 | 1235 | 2008 |
| Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair S Cortellino, J Xu, M Sannai, R Moore, E Caretti, A Cigliano, M Le Coz, ... Cell 146 (1), 67-79, 2011 | 971 | 2011 |
| The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines SJ Grille, A Bellacosa, J Upson, AJ Klein-Szanto, F Van Roy, W Lee-Kwon, ... Cancer research 63 (9), 2172-2178, 2003 | 850 | 2003 |
| Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis JG Goetz, S Minguet, I Navarro-Lérida, JJ Lazcano, R Samaniego, ... Cell 146 (1), 148-163, 2011 | 760 | 2011 |
| Skin tumor-promoting activity of benzoyl peroxide, a widely used free radical-generating compound TJ Slaga, AJP Klein-Szanto, LL Triplett, LP Yotti, JE Trosko Science 213 (4511), 1023-1025, 1981 | 619 | 1981 |
| AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth DA Altomare, HQ Wang, KL Skele, AD Rienzo, AJ Klein-Szanto, ... Oncogene 23 (34), 5853-5857, 2004 | 494 | 2004 |
| High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas. AB Bianchi, SI Mitsunaga, JQ Cheng, WM Klein, SC Jhanwar, B Seizinger, ... Proceedings of the National Academy of Sciences 92 (24), 10854-10858, 1995 | 429 | 1995 |
| Phosphorylation-dependent ubiquitination of cyclin D1 by the SCFFBX4-αB crystallin complex DI Lin, O Barbash, KGS Kumar, JD Weber, JW Harper, AJP Klein-Szanto, ... Molecular cell 24 (3), 355-366, 2006 | 427 | 2006 |
| Clinical implications of fibroblast activation protein in patients with colon cancer LR Henry, HO Lee, JS Lee, A Klein-Szanto, P Watts, EA Ross, WT Chen, ... Clinical cancer research 13 (6), 1736-1741, 2007 | 416 | 2007 |
| Increased expression of stem cell markers in malignant melanoma WM Klein, BP Wu, S Zhao, H Wu, AJP Klein-Szanto, SR Tahan Modern pathology 20 (1), 102-107, 2007 | 398 | 2007 |
| Influence of affinity and antigen internalization on the uptake and penetration of Anti-HER2 antibodies in solid tumors SI Rudnick, J Lou, CC Shaller, Y Tang, AJP Klein-Szanto, LM Weiner, ... Cancer research 71 (6), 2250-2259, 2011 | 377 | 2011 |
| Frequent activation of AKT in non-small cell lung carcinomas and preneoplastic bronchial lesions BR Balsara, J Pei, Y Mitsuuchi, R Page, A Klein-Szanto, H Wang, ... Carcinogenesis 25 (11), 2053-2059, 2004 | 368 | 2004 |
| Vascular endothelial growth factor is a marker of tumor invasion and metastasis in squamous cell carcinomas of the head and neck ER Sauter, M Nesbit, JC Watson, A Klein-Szanto, S Litwin, M Herlyn Clinical cancer research 5 (4), 775-782, 1999 | 343 | 1999 |
| The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma TY Seiwert, R Jagadeeswaran, L Faoro, V Janamanchi, V Nallasura, ... Cancer research 69 (7), 3021-3031, 2009 | 320 | 2009 |
| Mitochondria‐to‐nucleus stress signaling induces phenotypic changes, tumor progression and cell invasion G Amuthan, G Biswas, SY Zhang, A Klein‐Szanto, C Vijayasarathy, ... The EMBO journal, 2001 | 318 | 2001 |
| Disruption of the DT diaphorase (NQO1) gene in mice leads to increased menadione toxicity V Radjendirane, P Joseph, YH Lee, S Kimura, AJP Klein-Szanto, ... Journal of Biological Chemistry 273 (13), 7382-7389, 1998 | 316 | 1998 |
| Higher Frequency of Alterations in the p16/CDKN2 Gene in Squamous Cell Carcinoma Cell Lines Than in Primary Tumors of the Head and Neck SY Zhang, AJP Klein-Szanto, ER Sauter, M Shafarenko, S Mitsunaga, ... Cancer research 54 (19), 5050-5053, 1994 | 307 | 1994 |
| Mutations in transcript isoforms of the neurofibromatosis 2 gene in multiple human tumour types AB Bianchi, T Hara, V Ramesh, J Gao, AJP Klein-Szanto, F Morin, ... Nature genetics 6 (2), 185-192, 1994 | 297 | 1994 |
| Chemopotentiation of temozolomide, irinotecan, and cisplatin activity by CEP-6800, a poly (ADP-ribose) polymerase inhibitor SJ Miknyoczki, S Jones-Bolin, S Pritchard, K Hunter, H Zhao, W Wan, ... Molecular cancer therapeutics 2 (4), 371-382, 2003 | 290 | 2003 |
| Proprotein convertases:“master switches” in the regulation of tumor growth and progression DE Bassi, J Fu, R Lopez De Cicco, AJP Klein‐Szanto Molecular Carcinogenesis: Published in cooperation with the University of …, 2005 | 287 | 2005 |
J. Alan DiehlChair, Department of Biochemistry, Case Western Reserve UniversityVerified email at case.edu
