Masoud Vedadi
Masoud Vedadi
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Cited by
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The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability
FH Niesen, H Berglund, M Vedadi
Nature protocols 2 (9), 2212-2221, 2007
Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination
M Vedadi, FH Niesen, A Allali-Hassani, OY Fedorov, PJ Finerty Jr, ...
Proceedings of the National Academy of Sciences 103 (43), 15835-15840, 2006
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells
M Vedadi, D Barsyte-Lovejoy, F Liu, S Rival-Gervier, A Allali-Hassani, ...
Nature chemical biology 7 (8), 566-574, 2011
An orally bioavailable chemical probe of the lysine methyltransferases EZH2 and EZH1
KD Konze, A Ma, F Li, D Barsyte-Lovejoy, T Parton, CJ MacNevin, F Liu, ...
ACS chemical biology 8 (6), 1324-1334, 2013
Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth
J Zhu, MA Sammons, G Donahue, Z Dou, M Vedadi, M Getlik, ...
Nature 525 (7568), 206-211, 2015
Recognition and specificity determinants of the human cbx chromodomains
L Kaustov, H Ouyang, M Amaya, A Lemak, N Nady, S Duan, GA Wasney, ...
Journal of Biological Chemistry 286 (1), 521-529, 2011
Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity
A Schuetz, J Min, A Allali-Hassani, M Schapira, M Shuen, P Loppnau, ...
Journal of Biological Chemistry 283 (17), 11355-11363, 2008
Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms
M Vedadi, J Lew, J Artz, M Amani, Y Zhao, A Dong, GA Wasney, M Gao, ...
Molecular and biochemical parasitology 151 (1), 100-110, 2007
Structural biology of human H3K9 methyltransferases
H Wu, J Min, VV Lunin, T Antoshenko, L Dombrovski, H Zeng, ...
PloS one 5 (1), e8570, 2010
A strategy for modulation of enzymes in the ubiquitin system
A Ernst, G Avvakumov, J Tong, Y Fan, Y Zhao, P Alberts, A Persaud, ...
Science 339 (6119), 590-595, 2013
Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin
A Schuetz, J Min, T Antoshenko, CL Wang, A Allali-Hassani, A Dong, ...
Structure 15 (3), 377-389, 2007
In situ proteolysis for protein crystallization and structure determination
A Dong, X Xu, AM Edwards
Nature methods 4 (12), 1019-1021, 2007
Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors
W Yu, EJ Chory, AK Wernimont, W Tempel, A Scopton, A Federation, ...
Nature communications 3 (1), 1288, 2012
Structural and chemical profiling of the human cytosolic sulfotransferases
A Allali-Hassani, PW Pan, L Dombrovski, R Najmanovich, W Tempel, ...
PLoS biology 5 (5), e97, 2007
Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia
F Grebien, M Vedadi, M Getlik, R Giambruno, A Grover, R Avellino, ...
Nature chemical biology 11 (8), 571-578, 2015
Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP
F Liu, D Barsyte-Lovejoy, F Li, Y Xiong, V Korboukh, XP Huang, ...
Journal of medicinal chemistry 56 (21), 8931-8942, 2013
An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme
DF Ceccarelli, X Tang, B Pelletier, S Orlicky, W Xie, V Plantevin, ...
Cell 145 (7), 1075-1087, 2011
SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination
D Yanling Zhao, G Gish, U Braunschweig, Y Li, Z Ni, FW Schmitges, ...
Nature 529 (7584), 48-53, 2016
Discovery of a 2, 4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a
F Liu, X Chen, A Allali-Hassani, AM Quinn, GA Wasney, A Dong, ...
Journal of medicinal chemistry 52 (24), 7950-7953, 2009
Protein production: feeding the crystallographers and NMR spectroscopists
AM Edwards, CH Arrowsmith, D Christendat, A Dharamsi, JD Friesen, ...
nature structural biology 7 (11), 970-972, 2000
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