Shyam Khatau
Shyam Khatau
The Johns Hopkins University Institute for NanoBioTechnology
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A perinuclear actin cap regulates nuclear shape
SB Khatau, CM Hale, PJ Stewart-Hutchinson, MS Patel, CL Stewart, ...
Proceedings of the National Academy of Sciences 106 (45), 19017-19022, 2009
Nuclear lamin A/C deficiency induces defects in cell mechanics, polarization, and migration
JSH Lee, CM Hale, P Panorchan, SB Khatau, JP George, Y Tseng, ...
Biophysical journal 93 (7), 2542-2552, 2007
Dysfunctional connections between the nucleus and the actin and microtubule networks in laminopathic models
CM Hale, AL Shrestha, SB Khatau, PJ Stewart-Hutchinson, L Hernandez, ...
Biophysical journal 95 (11), 5462-5475, 2008
Actin cap associated focal adhesions and their distinct role in cellular mechanosensing
DH Kim, SB Khatau, Y Feng, S Walcott, SX Sun, GD Longmore, D Wirtz
Scientific reports 2 (1), 555, 2012
The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction
AB Chambliss, SB Khatau, N Erdenberger, DK Robinson, D Hodzic, ...
Scientific reports 3 (1), 1087, 2013
The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration
SB Khatau, RJ Bloom, S Bajpai, D Razafsky, S Zang, A Giri, PH Wu, ...
Scientific reports 2 (1), 488, 2012
Ballistic intracellular nanorheology reveals ROCK-hard cytoplasmic stiffening response to fluid flow
JSH Lee, P Panorchan, CM Hale, SB Khatau, TP Kole, Y Tseng, D Wirtz
Journal of cell science 119 (9), 1760-1768, 2006
Evolution of cellular morpho-phenotypes in cancer metastasis
PH Wu, JM Phillip, SB Khatau, WC Chen, J Stirman, S Rosseel, K Tschudi, ...
Scientific reports 5 (1), 18437, 2015
The perinuclear actin cap in health and disease
SB Khatau, DH Kim, CM Hale, RJ Bloom, D Wirtz
Nucleus 1 (4), 337-342, 2010
The differential formation of the LINC-mediated perinuclear actin cap in pluripotent and somatic cells
SB Khatau, S Kusuma, D Hanjaya-Putra, P Mali, L Cheng, JSH Lee, ...
PloS one 7 (5), e36689, 2012
SMRT analysis of MTOC and nuclear positioning reveals the role of EB1 and LIC1 in single-cell polarization
CM Hale, WC Chen, SB Khatau, BR Daniels, JSH Lee, D Wirtz
Journal of cell science 124 (24), 4267-4285, 2011
Differences in the microrheology of human embryonic stem cells and human induced pluripotent stem cells
BR Daniels, CM Hale, SB Khatau, S Kusuma, TM Dobrowsky, S Gerecht, ...
Biophysical journal 99 (11), 3563-3570, 2010
Tumor cell density regulates matrix metalloproteinases for enhanced migration
H Jayatilaka, FG Umanzor, V Shah, T Meirson, G Russo, B Starich, P Tyle, ...
Oncotarget 9 (66), 32556, 2018
EB1 and cytoplasmic dynein mediate protrusion dynamics for efficient 3-dimensional cell migration
H Jayatilaka, A Giri, M Karl, I Aifuwa, NJ Trenton, JM Phillip, S Khatau, ...
The FASEB Journal 32 (3), 1207, 2018
Functional interplay between the cell cycle and cell phenotypes
WC Chen, PH Wu, JM Phillip, SB Khatau, JM Choi, MR Dallas, ...
Integrative biology 5 (3), 523-534, 2013
Bundles from boundaries
D Wirtz, SB Khatau
Nature materials 9 (10), 788-790, 2010
System and device for characterizing cells
DG Wirtz, PH Wu, SB Khatau, WC Chen, JMG Phillip, ZA Binder, Y Tseng
US Patent 8,934,698, 2015
System and device for characterizing cells
D Wirtz, PH Wu, SB Khatau, W Chen, JM Phillip, ZA Binder, Y Tseng
US Patent 9,435,738, 2016
Investigation of cell morphology for disease diagnostics via high content screening
S Khatau
APS March Meeting Abstracts 2013, M46. 001, 2013
The distinct roles of nucleo-cytoskeleton connections in three-dimensional cell motility
SB Khatau, RJ Bloom, S Bajpai, D Razafsky, S Zang, A Celedon, CM Hale, ...
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