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Rami Al Batran
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Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency
KL Ho, L Zhang, C Wagg, R Al Batran, K Gopal, J Levasseur, T Leone, ...
Cardiovascular research 115 (11), 1606-1616, 2019
1442019
Impaired branched chain amino acid oxidation contributes to cardiac insulin resistance in heart failure
GM Uddin, L Zhang, S Shah, A Fukushima, CS Wagg, K Gopal, ...
Cardiovascular diabetology 18, 1-12, 2019
1222019
Targeting ceramide metabolism in obesity
H Aburasayn, R Al Batran, JR Ussher
American Journal of Physiology-Endocrinology And Metabolism 311 (2), E423-E435, 2016
1122016
Chronically elevating circulating ketones can reduce cardiac inflammation and blunt the development of heart failure
NJ Byrne, S Soni, S Takahara, M Ferdaoussi, R Al Batran, AM Darwesh, ...
Circulation: Heart Failure 13 (6), e006573, 2020
722020
Glucagon-like peptide-1 receptor action in the vasculature
M Almutairi, R Al Batran, JR Ussher
Peptides 111, 26-32, 2019
652019
FoxO1 regulates myocardial glucose oxidation rates via transcriptional control of pyruvate dehydrogenase kinase 4 expression
K Gopal, B Saleme, R Al Batran, H Aburasayn, A Eshreif, KL Ho, WK Ma, ...
American Journal of Physiology-Heart and Circulatory Physiology 313 (3 …, 2017
632017
Pimozide alleviates hyperglycemia in diet-induced obesity by inhibiting skeletal muscle ketone oxidation
R Al Batran, K Gopal, ME Capozzi, JJ Chahade, B Saleme, ...
Cell Metabolism 31 (5), 909-919. e8, 2020
462020
The GLP-1 receptor agonist liraglutide increases myocardial glucose oxidation rates via indirect mechanisms and mitigates experimental diabetic cardiomyopathy
M Almutairi, K Gopal, AA Greenwell, A Young, R Gill, H Aburasayn, ...
Canadian Journal of Cardiology 37 (1), 140-150, 2021
412021
Cardiac-specific Deletion of Pyruvate Dehydrogenase impairs glucose Oxidation rates and induces Diastolic Dysfunction
K Gopal, M Almutairi, R Al Batran, F Eaton, M Gandhi, JR Ussher
Frontiers in cardiovascular medicine 5, 17, 2018
332018
FoxO1 inhibition alleviates type 2 diabetes-related diastolic dysfunction by increasing myocardial pyruvate dehydrogenase activity
K Gopal, R Al Batran, TR Altamimi, AA Greenwell, CT Saed, SAT Dakhili, ...
Cell Reports 35 (1), 2021
312021
Cytosolic carnitine acetyltransferase as a source of cytosolic acetyl-CoA: a possible mechanism for regulation of cardiac energy metabolism
TR Altamimi, PD Thomas, AM Darwesh, N Fillmore, MU Mahmoud, ...
Biochemical Journal 475 (5), 959-976, 2018
312018
Glucagon-like peptide-1 receptor mediated control of cardiac energy metabolism
R Al Batran, M Almutairi, JR Ussher
Peptides 100, 94-100, 2018
222018
The antianginal ranolazine mitigates obesity-induced nonalcoholic fatty liver disease and increases hepatic pyruvate dehydrogenase activity
R Al Batran, K Gopal, H Aburasayn, A Eshreif, M Almutairi, AA Greenwell, ...
JCI insight 4 (1), 2019
202019
l‐Citrulline supplementation improves glucose and exercise tolerance in obese male mice
A Eshreif, R Al Batran, KL Jamieson, AM Darwesh, K Gopal, ...
Experimental Physiology 105 (2), 270-281, 2020
182020
Role of cytochrome p450 and soluble epoxide hydrolase enzymes and their associated metabolites in the pathogenesis of diabetic cardiomyopathy
ZH Maayah, E McGinn, R Al Batran, K Gopal, JR Ussher, AOS El-Kadi
Journal of Cardiovascular Pharmacology 74 (3), 235-245, 2019
142019
Dietary-induced obesity, hepatic cytochrome P450, and lidocaine metabolism: comparative effects of high-fat diets in mice and rats and reversibility of effects with …
HM Al Nebaihi, R Al Batran, JR Ussher, ZH Maayah, AOS El-Kadi, ...
Journal of Pharmaceutical Sciences 109 (2), 1199-1210, 2020
132020
Barth syndrome-related cardiomyopathy is associated with a reduction in myocardial glucose oxidation
AA Greenwell, K Gopal, TR Altamimi, CT Saed, F Wang, ...
American Journal of Physiology-Heart and Circulatory Physiology 320 (6 …, 2021
122021
Skeletal muscle-specific Cre recombinase expression, controlled by the human α-skeletal actin promoter, improves glucose tolerance in mice fed a high-fat diet
R Al Batran, K Gopal, MD Martin, KL Ho, M Almutairi, H Aburasayn, ...
Diabetologia 61, 1849-1855, 2018
102018
Revisiting protein acetylation and myocardial fatty acid oxidation
R Al Batran, JR Ussher
American Journal of Physiology-Heart and Circulatory Physiology, 2017
62017
Defective muscle ketone body oxidation disrupts BCAA catabolism by altering mitochondrial branched-chain aminotransferase
H Mechchate, AM Abdualkader, JB Bernacchi, K Gopal, ...
American Journal of Physiology-Endocrinology and Metabolism 324 (5), E425-E436, 2023
52023
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