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Ian David Coombs
Ian David Coombs
Experimental Officer, UCL
Verified email at ucl.ac.uk - Homepage
Title
Cited by
Cited by
Year
Stargazin attenuates intracellular polyamine block of calcium-permeable AMPA receptors
D Soto, ID Coombs, L Kelly, M Farrant, SG Cull-Candy
Nature neuroscience 10 (10), 1260-1267, 2007
2222007
Selective regulation of long-form calcium-permeable AMPA receptors by an atypical TARP, γ-5
D Soto, ID Coombs, M Renzi, M Zonouzi, M Farrant, SG Cull-Candy
Nature neuroscience 12 (3), 277-285, 2009
1262009
Cornichons modify channel properties of recombinant and glial AMPA receptors
ID Coombs, D Soto, M Zonouzi, M Renzi, C Shelley, M Farrant, ...
Journal of Neuroscience 32 (29), 9796-9804, 2012
1152012
Rare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study
P May, S Girard, M Harrer, DR Bobbili, J Schubert, S Wolking, F Becker, ...
The Lancet Neurology 17 (8), 699-708, 2018
892018
Transmembrane AMPA receptor regulatory proteins and AMPA receptor function in the cerebellum
ID Coombs, SG Cull-Candy
Neuroscience 162 (3), 656-665, 2009
722009
Molecular mechanisms contributing to TARP regulation of channel conductance and polyamine block of calcium-permeable AMPA receptors
D Soto, ID Coombs, E Gratacos-Batlle, M Farrant, SG Cull-Candy
Journal of Neuroscience 34 (35), 11673-11683, 2014
622014
TARP γ-7 selectively enhances synaptic expression of calcium-permeable AMPARs
D Studniarczyk, I Coombs, SG Cull-Candy, M Farrant
Nature neuroscience 16 (9), 1266-1274, 2013
612013
Dual effects of TARP γ-2 on glutamate efficacy can account for AMPA receptor autoinactivation
ID Coombs, DM MacLean, V Jayaraman, M Farrant, SG Cull-Candy
Cell reports 20 (5), 1123-1135, 2017
292017
Homomeric GluA2 (R) AMPA receptors can conduct when desensitized
ID Coombs, D Soto, TP McGee, MG Gold, M Farrant, SG Cull-Candy
Nature Communications 10 (1), 4312, 2019
252019
A gain‐of‐function GRIA2 variant associated with neurodevelopmental delay and seizures: Functional characterization and targeted treatment
ID Coombs, J Ziobro, V Krotov, TL Surtees, SG Cull‐Candy, M Farrant
Epilepsia 63 (12), e156-e163, 2022
102022
Single-channel mechanisms underlying the function, diversity and plasticity of AMPA receptors
ID Coombs, SG Cull-Candy
Neuropharmacology 198, 108781, 2021
72021
Influence of the TARP γ8-selective negative allosteric modulator JNJ-55511118 on AMPA receptor gating and channel conductance
ID Coombs, CA Sexton, SG Cull-Candy, M Farrant
Molecular Pharmacology 101 (5), 343-356, 2022
42022
Intracellular NASPM allows an unambiguous functional measure of GluA2-lacking calcium-permeable AMPA receptor prevalence
ID Coombs, C Bats, CA Sexton, SG Cull-Candy, M Farrant
bioRxiv, 2021.02. 18.431828, 2021
42021
Enhanced functional detection of synaptic calcium-permeable AMPA receptors using intracellular NASPM
I Coombs, C Bats, CA Sexton, D Studniarczyk, SG Cull-Candy, M Farrant
Elife 12, e66765, 2023
22023
Using electrophysiology to study synaptic and extrasynaptic ionotropic receptors in hippocampal neurons
ID Coombs, D Soto
Receptor and Ion Channel Detection in the Brain, 385-427, 2021
22021
Homomeric Q/R edited AMPA receptors conduct when desensitized
ID Coombs, D Soto, TP McGee, MG Gold, M Farrant, SG Cull-Candy
BioRxiv, 595009, 2019
22019
Multiple Subconductance States of Tarped AMPA Receptors Revealed by Slow Dissociation of Antagonist
I Coombs, A Tarasiuk, L Marconi, C Shelley, M Farrant, SG Cull-Candy
Biophysical Journal 112 (3), 418a, 2017
12017
An unexpected role for a glutamate receptor
ID Coombs, M Farrant
science 382 (6677), 1363-1364, 2023
2023
Role of CACNG2 variants in human pathology
S Cabet, A Maheshwari, J Noebels, A Goldman, M Farrant, S Cull-Candy, ...
2023
Glutamate Receptor Auxiliary Subunits and Interacting Protein Partners in the Cerebellum
ID Coombs, SG Cull-Candy
Handbook of the Cerebellum and Cerebellar Disorders, 929-955, 2021
2021
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