| Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood A Raue, C Kreutz, T Maiwald, J Bachmann, M Schilling, U Klingmüller, ... Bioinformatics 25 (15), 1923-1929, 2009 | 1545 | 2009 |
| Lessons learned from quantitative dynamical modeling in systems biology A Raue, M Schilling, J Bachmann, A Matteson, M Schelke, D Kaschek, ... PloS one 8 (9), e74335, 2013 | 411 | 2013 |
| Analysis of single-cell RNA-seq identifies cell-cell communication associated with tumor characteristics MP Kumar, J Du, G Lagoudas, Y Jiao, A Sawyer, DC Drummond, ... Cell reports 25 (6), 1458-1468. e4, 2018 | 401 | 2018 |
| Data2Dynamics: a modeling environment tailored to parameter estimation in dynamical systems A Raue, B Steiert, M Schelker, C Kreutz, T Maiwald, H Hass, J Vanlier, ... Bioinformatics 31 (21), 3558-3560, 2015 | 265 | 2015 |
| Estimation of immune cell content in tumour tissue using single-cell RNA-seq data M Schelker, S Feau, J Du, N Ranu, E Klipp, G MacBeath, B Schoeberl, ... Nature communications 8 (1), 2032, 2017 | 264 | 2017 |
| Comparison of approaches for parameter identifiability analysis of biological systems A Raue, J Karlsson, MP Saccomani, M Jirstrand, J Timmer Bioinformatics 30 (10), 1440-1448, 2014 | 238 | 2014 |
| Addressing parameter identifiability by model-based experimentation A Raue, C Kreutz, T Maiwald, U Klingmuller, J Timmer IET systems biology 5 (2), 120-130, 2011 | 211 | 2011 |
| Profile likelihood in systems biology C Kreutz, A Raue, D Kaschek, J Timmer The FEBS journal 280 (11), 2564-2571, 2013 | 207 | 2013 |
| Covering a broad dynamic range: information processing at the erythropoietin receptor V Becker, M Schilling, J Bachmann, U Baumann, A Raue, T Maiwald, ... Science 328 (5984), 1404-1408, 2010 | 205 | 2010 |
| Joining Forces of Bayesian and Frequentist Methodology: A Study for Inference in the Presence of Non-Identifiability A Raue, C Kreutz, F Theis, J Timmer Phil. Trans. Roy. Soc. A 371, 20110544, 2013 | 172 | 2013 |
| Identifiability and observability analysis for experimental design in nonlinear dynamical models A Raue, V Becker, U Klingmüller, J Timmer Chaos: An Interdisciplinary Journal of Nonlinear Science 20 (4), 2010 | 165 | 2010 |
| Likelihood based observability analysis and confidence intervals for predictions of dynamic models C Kreutz, A Raue, J Timmer BMC Systems Biology 6, 120, 2012 | 162 | 2012 |
| Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range J Bachmann, A Raue, M Schilling, ME Böhm, C Kreutz, D Kaschek, ... Molecular systems biology 7 (1), 516, 2011 | 152 | 2011 |
| Driving the model to its limit: profile likelihood based model reduction T Maiwald, H Hass, B Steiert, J Vanlier, R Engesser, A Raue, F Kipkeew, ... PloS one 11 (9), e0162366, 2016 | 104 | 2016 |
| Dynamic mathematical modeling of IL13-induced signaling in Hodgkin and primary mediastinal B-cell lymphoma allows prediction of therapeutic targets V Raia, M Schilling, M Böhm, B Hahn, A Kowarsch, A Raue, C Sticht, ... Cancer research 71 (3), 693-704, 2011 | 91 | 2011 |
| High-dimensional Bayesian parameter estimation: Case study for a model of JAK2/STAT5 signaling S Hug, A Raue, J Hasenauer, J Bachmann, U Klingmüller, J Timmer, ... Mathematical biosciences 246 (2), 293-304, 2013 | 87 | 2013 |
| Network topology and parameter estimation: from experimental design methods to gene regulatory network kinetics using a community based approach P Meyer, T Cokelaer, D Chandran, KH Kim, PR Loh, G Tucker, M Lipson, ... BMC systems biology 8, 1-18, 2014 | 79 | 2014 |
| Experimental design for parameter estimation of gene regulatory networks B Steiert, A Raue, J Timmer, C Kreutz PloS one 7 (7), e40052, 2012 | 79 | 2012 |
| Predictive mathematical models of cancer signalling pathways J Bachmann, A Raue, M Schilling, V Becker, J Timmer, U Klingmüller Journal of internal medicine 271 (2), 155-165, 2012 | 72 | 2012 |
| Bridging the gaps in systems biology M Cvijovic, J Almquist, J Hagmar, S Hohmann, HM Kaltenbach, E Klipp, ... Molecular Genetics and Genomics 289, 727-734, 2014 | 66 | 2014 |
Ursula KlingmüllerGerman Cancer Research Center (DKFZ)Verified email at dkfz-heidelberg.de
