Albert J. R. Heck

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Shabaz MohammedAssociate Professor of Proteomics, University of OxfordVerified email at bioch.ox.ac.uk
Maarten AltelaarProfessor, Universiteit UtrechtVerified email at uu.nl
Jeroen KrijgsveldGerman Cancer Research Center & Heidelberg UniversityVerified email at dkfz.de
Arjen ScholtenPrincipal Scientist Analytical Development; Janssen Vaccines & PreventionVerified email at its.jnj.com
Bas van BreukelenAssistant Professor, Biomolecular Mass Spectrometry and Proteomics Group, Utrecht UniversityVerified email at veluwestraat.nl
Teck Yew LowUKM Medical Molecular Biology InstituteVerified email at ppukm.ukm.edu.my
Reinout RaijmakersManaging Director, Bijvoet Center, Utrecht UniversityVerified email at uu.nl
Henk van den ToornBioinformatician at Biomolecular Mass Spectrometry and Proteomics Group, Utrecht UniversityVerified email at uu.nl
Joost SnijderUtrecht UniversityVerified email at uu.nl
Javier MuñozBiocruces BizkaiaVerified email at osakidetza.eus
Hans CleversHubrecht Institute - UtrechtVerified email at hubrecht.eu
Piero GiansantiChair of Proteomics and BioanalyticsVerified email at tum.de
Richard ScheltemaAssociate Professor at Utrecht UniversityVerified email at uu.nl
Alexander A. MakarovThermo Fisher ScientificVerified email at thermofisher.com
Fan LiuLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)Verified email at fmp-berlin.de
C. MummeryLeiden University Medical Centre and University of TwenteVerified email at lumc.nl
Fabio MarinoDipartimento di Scienze Chimiche, Farmaceutiche, Biologiche ed Ambientali. UNIME. CONISMA.Verified email at unime.it
Joost W. GouwScientist at Nutricia ResearchVerified email at interchange.ubc.ca
Daniele GuardavaccaroUniversity of VeronaVerified email at univr.it
Christian K. FreseBayerVerified email at bayer.com

Albert J. R. Heck

Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center and Utrecht University

Verified email at uu.nl - Homepage

Mass Spectrometry Proteomics Analytical Chemistry Stem Cells Pharmaceutical Sciences


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Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics PJ Boersema, R Raijmakers, S Lemeer, S Mohammed, AJR Heck Nature protocols 4 (4), 484-494, 2009	1465	2009
The CRAPome: a contaminant repository for affinity purification–mass spectrometry data D Mellacheruvu, Z Wright, AL Couzens, JP Lambert, NA St-Denis, T Li, ... Nature methods 10 (8), 730-736, 2013	1395	2013
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling W De Lau, N Barker, TY Low, BK Koo, VSW Li, H Teunissen, P Kujala, ... Nature 476 (7360), 293-297, 2011	1259	2011
Selective isolation at the femtomole level of phosphopeptides from proteolytic digests using 2D-NanoLC-ESI-MS/MS and titanium oxide precolumns MWH Pinkse, PM Uitto, MJ Hilhorst, B Ooms, AJR Heck Analytical chemistry 76 (14), 3935-3943, 2004	1082	2004
Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex VSW Li, SS Ng, PJ Boersema, TY Low, WR Karthaus, JP Gerlach, ... Cell 149 (6), 1245-1256, 2012	922	2012
Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors BK Koo, M Spit, I Jordens, TY Low, DE Stange, M Van De Wetering, ... Nature 488 (7413), 665-669, 2012	862	2012
Native mass spectrometry: a bridge between interactomics and structural biology AJR Heck Nature methods 5 (11), 927-933, 2008	796	2008
Next-generation proteomics: towards an integrative view of proteome dynamics AFM Altelaar, J Munoz, AJR Heck Nature Reviews Genetics 14 (1), 35-48, 2013	783	2013
The minimum information about a proteomics experiment (MIAPE) CF Taylor, NW Paton, KS Lilley, PA Binz, RK Julian Jr, AR Jones, W Zhu, ... Nature biotechnology 25 (8), 887-893, 2007	763	2007
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+ 4’cell markers J Muñoz, DE Stange, AG Schepers, M Van De Wetering, BK Koo, ... The EMBO journal 31 (14), 3079-3091, 2012	749	2012
Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis JJ Benschop, S Mohammed, M O'Flaherty, AJR Heck, M Slijper, ... Molecular & Cellular Proteomics 6 (7), 1198-1214, 2007	747	2007
Investigation of intact protein complexes by mass spectrometry AJR Heck, RHH Van Den Heuvel Mass spectrometry reviews 23 (5), 368-389, 2004	707	2004
RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions B Wiedenheft, E van Duijn, JB Bultema, SP Waghmare, K Zhou, ... Proceedings of the National Academy of Sciences 108 (25), 10092-10097, 2011	655	2011
Structural basis for CRISPR RNA-guided DNA recognition by Cascade MM Jore, M Lundgren, E Van Duijn, JB Bultema, ER Westra, ... Nature structural & molecular biology 18 (5), 529-536, 2011	642	2011
Complement is activated by IgG hexamers assembled at the cell surface CA Diebolder, FJ Beurskens, RN De Jong, RI Koning, K Strumane, ... Science 343 (6176), 1260-1263, 2014	630	2014
Ion mobility mass spectrometry of proteins and protein assemblies C Uetrecht, RJ Rose, E van Duijn, K Lorenzen, AJR Heck Chemical Society Reviews 39 (5), 1633-1655, 2010	520	2010
Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice E de Boer, P Rodriguez, E Bonte, J Krijgsveld, E Katsantoni, A Heck, ... Proceedings of the National Academy of Sciences 100 (13), 7480-7485, 2003	500	2003
Metabolic labeling of C. elegans and D. melanogaster for quantitative proteomics J Krijgsveld, RF Ketting, T Mahmoudi, J Johansen, M Artal-Sanz, ... Nature biotechnology 21 (8), 927-931, 2003	492	2003
Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7 R Rojas, T van Vlijmen, GA Mardones, Y Prabhu, AL Rojas, S Mohammed, ... The Journal of cell biology 183 (3), 513-526, 2008	482	2008
Native mass spectrometry: what is in the name? AC Leney, AJR Heck Journal of the American Society for Mass Spectrometry 28 (1), 5-13, 2016	481	2016

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