Challenges for targeting SARS-CoV-2 proteases as a therapeutic strategy for COVID-19 K Steuten, H Kim, JC Widen, BM Babin, O Onguka, S Lovell, O Bolgi, ... ACS infectious diseases 7 (6), 1457-1468, 2021 | 83 | 2021 |
Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting D Mavor, K Barlow, S Thompson, BA Barad, AR Bonny, CL Cario, ... Elife 5, e15802, 2016 | 78 | 2016 |
Measuring dynamic changes in the labile iron pool in vivo with a reactivity-based probe for positron emission tomography RK Muir, N Zhao, J Wei, Y Wang, A Moroz, Y Huang, YC Chen, R Sriram, ... ACS central science 5 (4), 727-736, 2019 | 37 | 2019 |
cAMP signaling regulates DNA hydroxymethylation by augmenting the intracellular labile ferrous iron pool V Camarena, DW Sant, TC Huff, S Mustafi, RK Muir, AT Aron, CJ Chang, ... Elife 6, e29750, 2017 | 34 | 2017 |
Ferronostics: measuring tumoral ferrous iron with PET to predict sensitivity to iron-targeted cancer therapies N Zhao, Y Huang, Y Wang, RK Muir, YC Chen, J Wei, N Hooshdaran, ... Journal of Nuclear Medicine 62 (7), 949-955, 2021 | 25 | 2021 |
Ferrous iron–activatable drug conjugate achieves potent MAPK blockade in KRAS-driven tumors H Jiang, RK Muir, RL Gonciarz, AB Olshen, I Yeh, BC Hann, N Zhao, ... Journal of Experimental Medicine 219 (4), e20210739, 2022 | 16 | 2022 |
Activity-based diagnostics: recent advances in the development of probes for use with diverse detection modalities RK Muir, M Guerra, MM Bogyo ACS Chemical Biology 17 (2), 281-291, 2022 | 15 | 2022 |
Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome I Deni, BH Stokes, KE Ward, KJ Fairhurst, CFA Pasaje, T Yeo, S Akbar, ... Cell chemical biology 30 (5), 470-485. e6, 2023 | 9 | 2023 |
Targeting Mobilization of Ferrous Iron in Pseudomonas aeruginosa Infection with an Iron(II)-Caged LpxC Inhibitor BR Blank, P Talukder, RK Muir, ER Green, EP Skaar, AR Renslo ACS infectious diseases 5 (8), 1366-1375, 2019 | 9 | 2019 |
Oscillatory cAMP signaling rapidly alters H3K4 methylation TC Huff, V Camarena, DW Sant, Z Wilkes, D Van Booven, AT Aron, ... Life science alliance 3 (1), 2020 | 6 | 2020 |
Cinnamomum zeylanicum Blume Essential Oil Inhibits Metastatic Melanoma Cell Proliferation by Triggering an Incomplete Tumour Cell Stress Response G Cappelli, D Giovannini, L Vilardo, A Basso, I Iannetti, M Massa, ... International Journal of Molecular Sciences 24 (6), 5698, 2023 | 4 | 2023 |
Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting. eLife 5 D Mavor, K Barlow, S Thompson, BA Barad, AR Bonny, CL Cario, ... Article e15802. doi, 2016 | 4 | 2016 |
Exploiting KRAS-driven ferroaddiction in cancer through ferrous iron-activatable drug conjugates (FeADC) H Jiang, RK Muir, RL Gonciarz, AB Olshen, I Yeh, BC Hann, N Zhao, ... bioRxiv, 2020.05. 12.088971, 2020 | 2 | 2020 |
Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum JM Bennett, KE Ward, RK Muir, S Kabeche, E Yoo, T Yeo, G Lam, ... ACS Infectious Diseases 9 (10), 2036-2047, 2023 | 1 | 2023 |
cAMP signaling regulates DNA demethylation by augmenting the intracellular labile ferrous iron pool V Camarena, DW Sant, TC Huff, S Mustafi, RK Muir, AR Renslo, P Monje, ... bioRxiv, 162743, 2017 | 1 | 2017 |
Mixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets JM Bennett, SK Narwal, S Kabeche, D Abegg, F Hackett, T Yeo, V Li, ... bioRxiv, 2024.01. 11.575224, 2024 | | 2024 |
Trioxolane agents AR Renslo, BR Blank, RK Muir, MJ Evans, P Talukder US Patent App. 17/680,825, 2022 | | 2022 |
Trioxolane agents AR Renslo, BR Blank, RK Muir, MJ Evans, P Talukder US Patent 11,072,594, 2021 | | 2021 |
Novel ferrous iron-dependent prodrug strategy for KRAS-driven pancreatic cancer: The preclinic efficacy and safety test H Jiang, R Muir, A Renslo, E Collisson Cancer Research 80 (16_Supplement), 6419-6419, 2020 | | 2020 |
Challenges for targeting SARS-CoV-2 proteases as a therapeutic strategy for COVID-19 (preprint) K Steuten, H Kim, JC Widen, BM Babin, O Onguka, S Lovell, O Bolgi, ... | | 2020 |