Maureen E Lynch
Maureen E Lynch
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Mesenchymal stem cells and insulin‐like growth factor‐I gene‐enhanced mesenchymal stem cells improve structural aspects of healing in equine flexor digitorum superficialis tendons
LV Schnabel, ME Lynch, MCH van der Meulen, AE Yeager, ...
Journal of Orthopaedic Research 27 (10), 1392-1398, 2009
Engineered culture models for studies of tumor-microenvironment interactions
DW Infanger, ME Lynch, C Fischbach
Annual review of biomedical engineering 15, 29-53, 2013
Tibial compression is anabolic in the adult mouse skeleton despite reduced responsiveness with aging
ME Lynch, RP Main, Q Xu, TL Schmicker, MB Schaffler, TM Wright, ...
Bone 49 (3), 439-446, 2011
Cancellous bone adaptation to tibial compression is not sex dependent in growing mice
ME Lynch, RP Main, Q Xu, DJ Walsh, MB Schaffler, TM Wright, ...
Journal of applied physiology 109 (3), 685-691, 2010
In vivo tibial compression decreases osteolysis and tumor formation in a human metastatic breast cancer model
ME Lynch, D Brooks, S Mohanan, MJ Lee, P Polamraju, K Dent, ...
Journal of Bone and Mineral Research 28 (11), 2357-2367, 2013
In vivo tibial stiffness is maintained by whole bone morphology and cross-sectional geometry in growing female mice
RP Main, ME Lynch, MCH van der Meulen
Journal of biomechanics 43 (14), 2689-2694, 2010
Multiscale characterization of the mineral phase at skeletal sites of breast cancer metastasis
F He, AE Chiou, HC Loh, M Lynch, BR Seo, YH Song, MJ Lee, R Hoerth, ...
Proceedings of the National Academy of Sciences 114 (40), 10542-10547, 2017
Load-induced changes in bone stiffness and cancellous and cortical bone mass following tibial compression diminish with age in female mice
RP Main, ME Lynch, MCH van der Meulen
Journal of Experimental Biology 217 (10), 1775-1783, 2014
The predictive link between matrix and metastasis
LE Barney, LE Jansen, SR Polio, S Galarza, ME Lynch, SR Peyton
Current opinion in chemical engineering 11, 85-93, 2016
Biomechanical forces in the skeleton and their relevance to bone metastasis: biology and engineering considerations
ME Lynch, C Fischbach
Advanced drug delivery reviews 79, 119-134, 2014
Three-dimensional mechanical loading modulates the osteogenic response of mesenchymal stem cells to tumor-derived soluble signals
ME Lynch, AE Chiou, MJ Lee, SC Marcott, PV Polamraju, Y Lee, ...
Tissue Engineering Part A 22 (15-16), 1006-1015, 2016
Mechanically-loaded breast cancer cells modify osteocyte mechanosensitivity by secreting factors that increase osteocyte dendrite formation and downstream resorption
W Wang, BA Sarazin, G Kornilowicz, ME Lynch
Frontiers in Endocrinology 9, 362409, 2018
Mechanical loading prevents bone destruction and exerts anti-tumor effects in the MOPC315. BM. Luc model of myeloma bone disease
M Rummler, F Ziouti, AL Bouchard, A Brandl, GN Duda, B Bogen, ...
Acta Biomaterialia 119, 247-258, 2021
Perfusion applied to a 3D model of bone metastasis results in uniformly dispersed mechanical stimuli
B Liu, S Han, BP Hedrick, Y Modarres‐Sadeghi, ME Lynch
Biotechnology and Bioengineering 115 (4), 1076-1085, 2018
Microgravity-induced alterations of mouse bones are compartment-and site-specific and vary with age
JC Coulombe, BA Sarazin, Z Mullen, AM Ortega, EW Livingston, ...
Bone 151, 116021, 2021
Mechanobiology of bone metastatic cancer
BA Sarazin, CL Ihle, P Owens, ME Lynch
Current osteoporosis reports, 1-12, 2021
The role of mechanobiology in cancer metastasis
ME Lynch, CP Neu, B Seelbinder, KP McCreery
Mechanobiology, 65-78, 2020
Multiphysics simulation of a compression–perfusion combined bioreactor to predict the mechanical microenvironment during bone metastatic breast cancer loading experiments
B Liu, S Han, Y Modarres‐Sadeghi, ME Lynch
Biotechnology and Bioengineering 118 (5), 1779-1792, 2021
Reduced local mechanical stimuli in spaceflight diminishes osteocyte lacunar morphometry and spatial heterogeneity in mouse cortical bone
JC Coulombe, ZA Mullen, AM Weins, LE Fisher, ME Lynch, LS Stodieck, ...
bioRxiv, 2022.01. 04.474962, 2022
Gene-enhanced mesenchymal stem cells improve tendinitis repair in a large animal model
L Schnabel, MA Kornatowski, AE Yeager, ME Lynch, MC van der Meulen, ...
Proceedings of the 53rd Orthopaedic Research Society 32, 502, 2007
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