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M P Blundell
M P Blundell
Verified email at ucl.ac.uk
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Year
Configuration of human dendritic cell cytoskeleton by Rho GTPases, the WAS protein, and differentiation
S Burns, AJ Thrasher, MP Blundell, L Machesky, GE Jones
Blood, The Journal of the American Society of Hematology 98 (4), 1142-1149, 2001
3992001
Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor γ chain
JP Goldman, MP Blundell, L Lopes, C Kinnon, JP DI Santo, AJ Thrasher
British journal of haematology 103 (2), 335-342, 1998
3081998
Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia
PJ Ancliff, MP Blundell, GO Cory, Y Calle, A Worth, H Kempski, S Burns, ...
Blood 108 (7), 2182-2189, 2006
2592006
Stable gene transfer to muscle using non-integrating lentiviral vectors
L Apolonia, SN Waddington, C Fernandes, NJ Ward, G Bouma, ...
Molecular Therapy 15 (11), 1947-1954, 2007
2332007
Deficiency in the Wiskott-Aldrich protein induces premature proplatelet formation and platelet production in the bone marrow compartment
S Sabri, A Foudi, S Boukour, B Franc, S Charrier, M Jandrot-Perrus, ...
Blood 108 (1), 134-140, 2006
2312006
Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia
DA Moulding, MP Blundell, DG Spiller, MRH White, GO Cory, Y Calle, ...
The Journal of experimental medicine 204 (9), 2213-2224, 2007
1892007
Valproic acid confers functional pluripotency to human amniotic fluid stem cells in a transgene-free approach
D Moschidou, S Mukherjee, MP Blundell, K Drews, GN Jones, ...
Molecular Therapy 20 (10), 1953-1967, 2012
1752012
A ubiquitous chromatin opening element (UCOE) confers resistance to DNA methylation–mediated silencing of lentiviral vectors
F Zhang, AR Frost, MP Blundell, O Bales, MN Antoniou, AJ Thrasher
Molecular therapy 18 (9), 1640-1649, 2010
1632010
Biochemical correction of X-CGD by a novel chimeric promoter regulating high levels of transgene expression in myeloid cells
G Santilli, E Almarza, C Brendel, U Choi, C Beilin, MP Blundell, S Haria, ...
Molecular Therapy 19 (1), 122-132, 2011
1612011
Cutting edge: the Wiskott-Aldrich syndrome protein is required for efficient phagocytosis of apoptotic cells
Y Leverrier, R Lorenzi, MP Blundell, P Brickell, C Kinnon, AJ Ridley, ...
The Journal of Immunology 166 (8), 4831-4834, 2001
1512001
Impaired dendritic-cell homing in vivo in the absence of Wiskott-Aldrich syndrome protein
S de Noronha, S Hardy, J Sinclair, MP Blundell, J Strid, O Schulz, ...
Blood 105 (4), 1590-1597, 2005
1492005
The Wiskott-Aldrich syndrome: the actin cytoskeleton and immune cell function
MP Blundell, A Worth, G Bouma, AJ Thrasher
Disease markers 29 (3-4), 157-175, 2010
1442010
WASp deficiency in mice results in failure to form osteoclast sealing zones and defects in bone resorption
Y Calle, GE Jones, C Jagger, K Fuller, MP Blundell, J Chow, T Chambers, ...
Blood 103 (9), 3552-3561, 2004
1432004
Lentiviral vectors targeting WASp expression to hematopoietic cells, efficiently transduce and correct cells from WAS patients
S Charrier, L Dupre, S Scaramuzza, L Jeanson-Leh, MP Blundell, ...
Gene therapy 14 (5), 415-428, 2007
1362007
Autoinflammatory periodic fever, immunodeficiency, and thrombocytopenia (PFIT) caused by mutation in actin-regulatory gene WDR1
ASI Standing, D Malinova, Y Hong, J Record, D Moulding, MP Blundell, ...
Journal of Experimental Medicine 214 (1), 59-71, 2017
1342017
Restoration of podosomes and chemotaxis in Wiskott–Aldrich syndrome macrophages following induced expression of WASp
GE Jones, D Zicha, GA Dunn, M Blundell, A Thrasher
The international journal of biochemistry & cell biology 34 (7), 806-815, 2002
1252002
Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membrane
H Schachtner, SDJ Calaminus, A Sinclair, J Monypenny, MP Blundell, ...
Blood, The Journal of the American Society of Hematology 121 (13), 2542-2552, 2013
1222013
Nonintegrating lentivector vaccines stimulate prolonged T-cell and antibody responses and are effective in tumor therapy
K Karwacz, S Mukherjee, L Apolonia, MP Blundell, G Bouma, D Escors, ...
Journal of Virology 83 (7), 3094-3103, 2009
1012009
Preclinical demonstration of lentiviral vector-mediated correction of immunological and metabolic abnormalities in models of adenosine deaminase deficiency
DA Carbonaro, L Zhang, X Jin, C Montiel-Equihua, S Geiger, M Carmo, ...
Molecular Therapy 22 (3), 607-622, 2014
972014
Cytoskeletal remodeling mediated by WASp in dendritic cells is necessary for normal immune synapse formation and T-cell priming
G Bouma, A Mendoza-Naranjo, MP Blundell, E De Falco, KL Parsley, ...
Blood, The Journal of the American Society of Hematology 118 (9), 2492-2501, 2011
972011
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