| Empagliflozin increases cardiac energy production in diabetes: novel translational insights into the heart failure benefits of SGLT2 inhibitors S Verma, S Rawat, KL Ho, CS Wagg, L Zhang, H Teoh, JE Dyck, ... JACC: Basic to Translational Science 3 (5), 575-587, 2018 | 359 | 2018 |
| Cardiac insulin-resistance and decreased mitochondrial energy production precede the development of systolic heart failure after pressure-overload hypertrophy L Zhang, JS Jaswal, JR Ussher, S Sankaralingam, C Wagg, M Zaugg, ... Circulation: Heart Failure 6 (5), 1039-1048, 2013 | 260 | 2013 |
| Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling OA Alrob, S Sankaralingam, C Ma, CS Wagg, N Fillmore, JS Jaswal, ... Cardiovascular research 103 (4), 485-497, 2014 | 214 | 2014 |
| Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury JR Ussher, W Wang, M Gandhi, W Keung, V Samokhvalov, T Oka, ... Cardiovascular research 94 (2), 359-369, 2012 | 195 | 2012 |
| Angiotensin 1–7 Ameliorates Diabetic Cardiomyopathy and Diastolic Dysfunction in db/db Mice by Reducing Lipotoxicity and Inflammation J Mori, VB Patel, O Abo Alrob, R Basu, T Altamimi, J DesAulniers, ... Circulation: Heart Failure 7 (2), 327-339, 2014 | 194 | 2014 |
| ANG II causes insulin resistance and induces cardiac metabolic switch and inefficiency: a critical role of PDK4 J Mori, OA Alrob, CS Wagg, RA Harris, GD Lopaschuk, GY Oudit American Journal of Physiology-Heart and Circulatory Physiology 304 (8 …, 2013 | 178 | 2013 |
| Fatty acid translocase/CD36 deficiency does not energetically or functionally compromise hearts before or after ischemia M Kuang, M Febbraio, C Wagg, GD Lopaschuk, JRB Dyck Circulation 109 (12), 1550-1557, 2004 | 172 | 2004 |
| Agonist-induced hypertrophy and diastolic dysfunction are associated with selective reduction in glucose oxidation: a metabolic contribution to heart failure with normal … J Mori, R Basu, BA McLean, SK Das, L Zhang, VB Patel, CS Wagg, ... Circulation: Heart Failure 5 (4), 493-503, 2012 | 171 | 2012 |
| Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation L Zhang, JR Ussher, T Oka, VJJ Cadete, C Wagg, GD Lopaschuk Cardiovascular research 89 (1), 148-156, 2011 | 151 | 2011 |
| Chronic activation of PPARα is detrimental to cardiac recovery after ischemia N Sambandam, D Morabito, C Wagg, BN Finck, DP Kelly, GD Lopaschuk American Journal of Physiology-Heart and Circulatory Physiology 290 (1), H87-H95, 2006 | 149 | 2006 |
| Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency KL Ho, L Zhang, C Wagg, R Al Batran, K Gopal, J Levasseur, T Leone, ... Cardiovascular research 115 (11), 1606-1616, 2019 | 148 | 2019 |
| Inhibition of carnitine palmitoyltransferase-1 activity alleviates insulin resistance in diet-induced obese mice W Keung, JR Ussher, JS Jaswal, M Raubenheimer, VHM Lam, CS Wagg, ... Diabetes 62 (3), 711-720, 2013 | 144 | 2013 |
| Impaired branched chain amino acid oxidation contributes to cardiac insulin resistance in heart failure GM Uddin, L Zhang, S Shah, A Fukushima, CS Wagg, K Gopal, ... Cardiovascular diabetology 18, 1-12, 2019 | 124 | 2019 |
| Thioredoxin-interacting protein deficiency disrupts the fasting-feeding metabolic transition SS Sheth, LW Castellani, S Chari, C Wagg, CK Thipphavong, JS Bodnar, ... Journal of lipid research 46 (1), 123-134, 2005 | 122 | 2005 |
| Chronic inhibition of pyruvate dehydrogenase in heart triggers an adaptive metabolic response KT Chambers, TC Leone, N Sambandam, A Kovacs, CS Wagg, ... Journal of Biological Chemistry 286 (13), 11155-11162, 2011 | 114 | 2011 |
| Failing mouse hearts utilize energy inefficiently and benefit from improved coupling of glycolysis and glucose oxidation WGT Masoud, JR Ussher, W Wang, JS Jaswal, CS Wagg, JR Dyck, ... Cardiovascular research 101 (1), 30-38, 2014 | 97 | 2014 |
| Uncoupling of glycolysis from glucose oxidation accompanies the development of heart failure with preserved ejection fraction N Fillmore, JL Levasseur, A Fukushima, CS Wagg, W Wang, JRB Dyck, ... Molecular medicine 24, 1-12, 2018 | 96 | 2018 |
| Acetylation and succinylation contribute to maturational alterations in energy metabolism in the newborn heart A Fukushima, OA Alrob, L Zhang, CS Wagg, T Altamimi, S Rawat, ... American Journal of Physiology-Heart and Circulatory Physiology 311 (2 …, 2016 | 80 | 2016 |
| Diastolic dysfunction in familial hypertrophic cardiomyopathy transgenic model mice TP Abraham, M Jones, K Kazmierczak, HY Liang, AC Pinheiro, CS Wagg, ... Cardiovascular research 82 (1), 84-92, 2009 | 77 | 2009 |
| Ketones can become the major fuel source for the heart but do not increase cardiac efficiency KL Ho, QG Karwi, C Wagg, L Zhang, K Vo, T Altamimi, GM Uddin, ... Cardiovascular research 117 (4), 1178-1187, 2021 | 74 | 2021 |
