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Alexey Revenko
Alexey Revenko
Executive Director Oncology, IONIS Pharmaceuticals
Verified email at ionisph.com
Title
Cited by
Cited by
Year
The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells
T Gutschner, M Hämmerle, M Eißmann, J Hsu, Y Kim, G Hung, A Revenko, ...
Cancer research 73 (3), 1180-1189, 2013
17042013
AZD9150, a next-generation antisense oligonucleotide inhibitor of STAT3 with early evidence of clinical activity in lymphoma and lung cancer
D Hong, R Kurzrock, Y Kim, R Woessner, A Younes, J Nemunaitis, ...
Science translational medicine 7 (314), 314ra185-314ra185, 2015
4372015
Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding
AS Revenko, D Gao, JR Crosby, G Bhattacharjee, C Zhao, C May, ...
Blood, The Journal of the American Society of Hematology 118 (19), 5302-5311, 2011
2372011
Inhibition of the intrinsic coagulation pathway factor XI by antisense oligonucleotides: a novel antithrombotic strategy with lowered bleeding risk
H Zhang, EC Löwenberg, JR Crosby, AR MacLeod, C Zhao, D Gao, ...
Blood, The Journal of the American Society of Hematology 116 (22), 4684-4692, 2010
2232010
STAT3 antisense oligonucleotide AZD9150 in a subset of patients with heavily pretreated lymphoma: results of a phase 1b trial
MJ Reilley, P McCoon, C Cook, P Lyne, R Kurzrock, Y Kim, R Woessner, ...
Journal for immunotherapy of cancer 6, 1-10, 2018
1952018
Targeting KRAS-dependent tumors with AZD4785, a high-affinity therapeutic antisense oligonucleotide inhibitor of KRAS
SJ Ross, AS Revenko, LL Hanson, R Ellston, A Staniszewska, N Whalley, ...
Science translational medicine 9 (394), eaal5253, 2017
1822017
ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb …
EV Kalashnikova, AS Revenko, AT Gemo, NP Andrews, CG Tepper, ...
Cancer research 70 (22), 9402-9412, 2010
1802010
ANCCA, an estrogen-regulated AAA+ ATPase coactivator for ERα, is required for coregulator occupancy and chromatin modification
JX Zou, AS Revenko, LB Li, AT Gemo, HW Chen
Proceedings of the National Academy of Sciences 104 (46), 18067-18072, 2007
1802007
Selective depletion of factor XI or factor XII with antisense oligonucleotides attenuates catheter thrombosis in rabbits
JW Yau, P Liao, JC Fredenburgh, AR Stafford, AS Revenko, BP Monia, ...
Blood, The Journal of the American Society of Hematology 123 (13), 2102-2107, 2014
1732014
Androgen-induced coactivator ANCCA mediates specific androgen receptor signaling in prostate cancer
JX Zou, L Guo, AS Revenko, CG Tepper, AT Gemo, HJ Kung, HW Chen
Cancer research 69 (8), 3339-3346, 2009
1652009
Antithrombotic effect of antisense factor XI oligonucleotide treatment in primates
JR Crosby, U Marzec, AS Revenko, C Zhao, D Gao, A Matafonov, ...
Arteriosclerosis, thrombosis, and vascular biology 33 (7), 1670-1678, 2013
1622013
Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark
AS Revenko, EV Kalashnikova, AT Gemo, JX Zou, HW Chen
Molecular and cellular biology 30 (22), 5260-5272, 2010
1302010
Colon cancer growth and dissemination relies upon thrombin, stromal PAR-1, and fibrinogen
GN Adams, L Rosenfeldt, M Frederick, W Miller, D Waltz, K Kombrinck, ...
Cancer research 75 (19), 4235-4243, 2015
1272015
Asialoglycoprotein receptor 1 mediates productive uptake of N-acetylgalactosamine-conjugated and unconjugated phosphorothioate antisense oligonucleotides …
M Tanowitz, L Hettrick, A Revenko, GA Kinberger, TP Prakash, PP Seth
Nucleic acids research 45 (21), 12388-12400, 2017
1252017
New developments in anticoagulants: past, present and future
JI Weitz, J Harenberg
Thrombosis and haemostasis 117 (07), 1283-1288, 2017
1092017
Direct control of cell cycle gene expression by proto-oncogene product ACTR, and its autoregulation underlies its transforming activity
MC Louie, AS Revenko, JX Zou, J Yao, HW Chen
Molecular and cellular biology 26 (10), 3810-3823, 2006
892006
Differential uptake, kinetics and mechanisms of intracellular trafficking of next-generation antisense oligonucleotides across human cancer cell lines
E Linnane, P Davey, P Zhang, S Puri, M Edbrooke, E Chiarparin, ...
Nucleic acids research 47 (9), 4375-4392, 2019
812019
Depletion of coagulation factor XII ameliorates brain pathology and cognitive impairment in Alzheimer disease mice
ZL Chen, AS Revenko, P Singh, AR MacLeod, EH Norris, S Strickland
Blood, The Journal of the American Society of Hematology 129 (18), 2547-2556, 2017
792017
Modulation of tumor eIF4E by antisense inhibition: A phase I/II translational clinical trial of ISIS 183750—an antisense oligonucleotide against eIF4E—in combination with …
AG Duffy, OV Makarova‐Rusher, SV Ulahannan, OE Rahma, S Fioravanti, ...
International journal of cancer 139 (7), 1648-1657, 2016
752016
Deregulated E2F and the AAA+ coregulator ANCCA drive proto-oncogene ACTR/AIB1 overexpression in breast cancer
EYC Hsia, EV Kalashnikova, AS Revenko, JX Zou, AD Borowsky, ...
Molecular cancer research 8 (2), 183-193, 2010
712010
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