| Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer’s disease B Zhang, C Gaiteri, LG Bodea, Z Wang, J McElwee, AA Podtelezhnikov, ... Cell 153 (3), 707-720, 2013 | 1717 | 2013 |
| Phase I pharmacologic and pharmacodynamic study of the gamma secretase (Notch) inhibitor MK-0752 in adult patients with advanced solid tumors I Krop, T Demuth, T Guthrie, PY Wen, WP Mason, P Chinnaiyan, ... Journal of clinical oncology 30 (19), 2307-2313, 2012 | 343 | 2012 |
| Transcriptional architecture of the primate neocortex A Bernard, LS Lubbers, KQ Tanis, R Luo, AA Podtelezhnikov, EM Finney, ... Neuron 73 (6), 1083-1099, 2012 | 246 | 2012 |
| Mechanism of topology simplification by type II DNA topoisomerases AV Vologodskii, W Zhang, VV Rybenkov, AA Podtelezhnikov, ... Proceedings of the National Academy of Sciences 98 (6), 3045-3049, 2001 | 187 | 2001 |
| Large-scale effects of transcriptional DNA supercoiling in vivo AS Krasilnikov, A Podtelezhnikov, A Vologodskii, SM Mirkin Journal of molecular biology 292 (5), 1149-1160, 1999 | 111 | 1999 |
| Molecular insights into the pathogenesis of Alzheimer's disease and its relationship to normal aging AA Podtelezhnikov, KQ Tanis, M Nebozhyn, WJ Ray, DJ Stone, ... PloS one 6 (12), e29610, 2011 | 97 | 2011 |
| Comparative transcriptomics of choroid plexus in Alzheimer’s disease, frontotemporal dementia and Huntington’s disease: implications for CSF homeostasis EG Stopa, KQ Tanis, MC Miller, EV Nikonova, AA Podtelezhnikov, ... Fluids and Barriers of the CNS 15, 1-10, 2018 | 94 | 2018 |
| Blood-gene expression reveals reduced circadian rhythmicity in individuals resistant to sleep deprivation ES Arnardottir, EV Nikonova, KR Shockley, AA Podtelezhnikov, RC Anafi, ... Sleep 37 (10), 1589-1600, 2014 | 84 | 2014 |
| Modeling HIV‐1 integrase complexes based on their hydrodynamic properties AA Podtelezhnikov, K Gao, FD Bushman, JA McCammon Biopolymers: Original Research on Biomolecules 68 (1), 110-120, 2003 | 81 | 2003 |
| Equilibrium distributions of topological states in circular DNA: interplay of supercoiling and knotting AA Podtelezhnikov, NR Cozzarelli, AV Vologodskii Proceedings of the National Academy of Sciences 96 (23), 12974-12979, 1999 | 80 | 1999 |
| Simulations of polymer cyclization by Brownian dynamics A Podtelezhnikov, A Vologodskii Macromolecules 30 (21), 6668-6673, 1997 | 77 | 1997 |
| Multimerization-cyclization of DNA fragments as a method of conformational analysis AA Podtelezhnikov, C Mao, NC Seeman, A Vologodskii Biophysical Journal 79 (5), 2692-2704, 2000 | 69 | 2000 |
| The transcriptomic signature of disease development and progression of nonalcoholic fatty liver disease S Cazanave, A Podtelezhnikov, K Jensen, M Seneshaw, DP Kumar, ... Scientific reports 7 (1), 17193, 2017 | 60 | 2017 |
| Discovering biology in periodic data through phase set enrichment analysis (PSEA) R Zhang, AA Podtelezhnikov, JB Hogenesch, RC Anafi Journal of biological rhythms 31 (3), 244-257, 2016 | 59 | 2016 |
| Dynamics of small loops in DNA molecules AA Podtelezhnikov, AV Vologodskii Macromolecules 33 (7), 2767-2771, 2000 | 53 | 2000 |
| Bayesian segmental models with multiple sequence alignment profiles for protein secondary structure and contact map prediction W Chu, Z Ghahramani, A Podtelezhnikov, DL Wild IEEE/ACM transactions on computational biology and bioinformatics 3 (2), 98-113, 2006 | 43 | 2006 |
| Network-driven plasma proteomics expose molecular changes in the Alzheimer’s brain PA Jaeger, KM Lucin, M Britschgi, B Vardarajan, RP Huang, ED Kirby, ... Molecular neurodegeneration 11, 1-18, 2016 | 38 | 2016 |
| Application of a rat liver drug bioactivation transcriptional response assay early in drug development that informs chemically reactive metabolite formation and potential for … JJ Monroe, KQ Tanis, AA Podtelezhnikov, T Nguyen, SV Machotka, ... Toxicological Sciences 177 (1), 281-299, 2020 | 32 | 2020 |
| Exhaustive Metropolis Monte Carlo sampling and analysis of polyalanine conformations adopted under the influence of hydrogen bonds AA Podtelezhnikov, DL Wild Proteins: Structure, Function, and Bioinformatics 61 (1), 94-104, 2005 | 28 | 2005 |
| Development and Application of a Transcriptomic Signature of Bioactivation in an Advanced In Vitro Liver Model to Reduce Drug-induced Liver Injury Risk Early in … W Kang, AA Podtelezhnikov, KQ Tanis, S Pacchione, M Su, KB Bleicher, ... Toxicological Sciences 177 (1), 121-139, 2020 | 26 | 2020 |
Keith Q. TanisPrincipal Scientist, Merck & Co.Verified email at merck.com
