|A synthetic curcuminoid derivative inhibits nitric oxide and proinflammatory cytokine synthesis|
CL Tham, CY Liew, KW Lam, AS Mohamad, MK Kim, YK Cheah, ...
European journal of pharmacology 628 (1-3), 247-254, 2010
|New class of acetylcholinesterase inhibitors from the stem bark of Knema laurina and their structural insights|
MN Akhtar, KW Lam, F Abas, S Ahmad, SAA Shah, MI Choudhary, ...
Bioorganic & medicinal chemistry letters 21 (13), 4097-4103, 2011
|Synthesis and sar study of diarylpentanoid analogues as new anti-inflammatory agents|
SW Leong, SMM Faudzi, F Abas, MFFM Aluwi, K Rullah, LK Wai, ...
Molecules 19 (10), 16058-16081, 2014
|Synthesis and biological activity of oxadiazole and triazolothiadiazole derivatives as tyrosinase inhibitors|
KW Lam, A Syahida, Z Ul-Haq, MBA Rahman, NH Lajis
Bioorganic & medicinal chemistry letters 20 (12), 3755-3759, 2010
|Bioassay-guided identification of an anti-inflammatory prenylated acylphloroglucinol from Melicope ptelefolia and molecular insights into its interaction with 5-lipoxygenase|
K Shaari, V Suppaiah, LK Wai, J Stanslas, BA Tejo, DA Israf, F Abas, ...
Bioorganic & medicinal chemistry 19 (21), 6340-6347, 2011
|Synthesis of unsymmetrical monocarbonyl curcumin analogues with potent inhibition on prostaglandin E2 production in LPS-induced murine and human macrophages cell lines|
MFFM Aluwi, K Rullah, BM Yamin, SW Leong, MNA Bahari, SJ Lim, ...
Bioorganic & medicinal chemistry letters 26 (10), 2531-2538, 2016
|Synthesis and evaluation of chalcone derivatives as inhibitors of neutrophils' chemotaxis, phagocytosis and production of reactive oxygen species|
SNA Bukhari, Y Tajuddin, VJ Benedict, KW Lam, I Jantan, J Jalil, ...
Chemical biology & drug design 83 (2), 198-206, 2014
|Effects of diarylpentanoid analogues of curcumin on chemiluminescence and chemotactic activities of phagocytes|
I Jantan, SNA Bukhari, NH Lajis, F Abas, LK Wai, M Jasamai
Journal of Pharmacy and Pharmacology 64 (3), 404-412, 2012
|Nitric oxide inhibitory activity and antioxidant evaluations of 2-benzoyl-6-benzylidenecyclohexanone analogs, a novel series of curcuminoid and diarylpentanoid derivatives|
SW Leong, SMM Faudzi, F Abas, MFFM Aluwi, K Rullah, KW Lam, ...
Bioorganic & medicinal chemistry letters 25 (16), 3330-3337, 2015
|Inhibition of prostaglandin E2 production by synthetic minor prenylated chalcones and flavonoids: Synthesis, biological activity, crystal structure, and in silico evaluation|
K Rullah, MFFM Aluwi, BM Yamin, MNA Bahari, LS Wei, S Ahmad, F Abas, ...
Bioorganic & medicinal chemistry letters 24 (16), 3826-3834, 2014
|The effects of a synthetic curcuminoid analogue, 2, 6-bis-(4-hydroxyl-3-methoxybenzylidine) cyclohexanone on proinflammatory signaling pathways and CLP-induced lethal sepsis in …|
CL Tham, KW Lam, R Rajajendram, YK Cheah, MR Sulaiman, NH Lajis, ...
European journal of pharmacology 652 (1-3), 136-144, 2011
|Synthesis, biological evaluation and QSAR studies of diarylpentanoid analogues as potential nitric oxide inhibitors|
SMM Faudzi, SW Leong, F Abas, MFFM Aluwi, K Rullah, KW Lam, ...
MedChemComm 6 (6), 1069-1080, 2015
|Physicochemical Evaluation and Spectroscopic Characterisation of Gelatine from Shank and Toes of Gallus gallus d...|
Sains Malaysiana 45 (3), 435-449, 2016
|Effects of 3-(2-Hydroxyphenyl)-1-(5-methyl-furan-2-yl) propenone (HMP) upon signalling pathways of lipopolysaccharide-induced iNOS synthesis in RAW 264.7 cells|
CY Liew, KW Lam, MK Kim, HH Harith, CL Tham, YK Cheah, ...
International immunopharmacology 11 (1), 85-95, 2011
|Synthesis and QSAR analysis of chalcone derivatives as nitric oxide inhibitory agent|
KW Lam, R Uddin, CY Liew, CL Tham, DA Israf, A Syahida, MBA Rahman, ...
Medicinal Chemistry Research 21 (8), 1953-1966, 2012
|Molecular docking analysis of selected Clinacanthus nutans constituents as xanthine oxidase, nitric oxide synthase, human neutrophil elastase, matrix metalloproteinase 2 …|
AI Radhakrishnan Narayanaswamy, LK Wai, IS Ismail
Pharmacognosy magazine 12 (Suppl 1), S21, 2016
|Synthesis of damnacanthal, a naturally occurring 9, 10-anthraquinone and its analogues, and its biological evaluation against five cancer cell lines|
K Saha, KW Lam, F Abas, AS Hamzah, J Stanslas, LS Hui, NH Lajis
Medicinal Chemistry Research 22 (5), 2093-2104, 2013
|Synthesis and evaluation of DPPH and anti-inflammatory activities of 2, 6-bisbenzylidenecyclohexanone and pyrazoline derivatives|
KW Lam, CL Tham, CY Liew, A Syahida, MBA Rahman, DA Israf, NH Lajis
Medicinal Chemistry Research 21 (3), 333-344, 2012
|Synthesis, characterization, acetylcholinesterase inhibition, molecular modeling and antioxidant activities of some novel schiff bases derived from 1-(2-ketoiminoethyl) piperazines|
SM Salga, HM Ali, MA Abdullah, SI Abdelwahab, LK Wai, MJC Buckle, ...
Molecules 16 (11), 9316-9330, 2011
|2-Benzoyl-6-benzylidenecyclohexanone analogs as potent dual inhibitors of acetylcholinesterase and butyrylcholinesterase|
SW Leong, F Abas, KW Lam, K Shaari, NH Lajis
Bioorganic & medicinal chemistry 24 (16), 3742-3751, 2016