| Mutations in the tuberous sclerosis complex gene TSC2 are a cause of sporadic pulmonary lymphangioleiomyomatosis T Carsillo, A Astrinidis, EP Henske Proceedings of the National Academy of Sciences 97 (11), 6085-6090, 2000 | 747 | 2000 |
| Recurrent lymphangiomyomatosis after transplantation: genetic analyses reveal a metastatic mechanism M Karbowniczek, A Astrinidis, BR Balsara, JR Testa, JH Lium, TV Colby, ... American journal of respiratory and critical care medicine 167 (7), 976-982, 2003 | 312 | 2003 |
| Tuberous sclerosis complex: linking growth and energy signaling pathways with human disease A Astrinidis, EP Henske Oncogene 24 (50), 7475-7481, 2005 | 257 | 2005 |
| Estradiol and tamoxifen stimulate LAM-associated angiomyolipoma cell growth and activate both genomic and nongenomic signaling pathways J Yu, A Astrinidis, S Howard, EP Henske American Journal of Physiology-Lung Cellular and Molecular Physiology 286 (4 …, 2004 | 226 | 2004 |
| Estrogen promotes the survival and pulmonary metastasis of tuberin-null cells JJ Yu, VA Robb, TA Morrison, EA Ariazi, M Karbowniczek, A Astrinidis, ... Proceedings of the National Academy of Sciences 106 (8), 2635-2640, 2009 | 195 | 2009 |
| Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration A Astrinidis, TP Cash, DS Hunter, CL Walker, J Chernoff, EP Henske Oncogene 21 (55), 8470-8476, 2002 | 187 | 2002 |
| Chromosome 16 loss of heterozygosity in tuberous sclerosis and sporadic lymphangiomyomatosis J Yu, A ASTRINIDIS, EP HENSKE American Journal of Respiratory and Critical Care Medicine 164 (8), 1537-1540, 2001 | 168 | 2001 |
| Mutational analysis of the tuberous sclerosis geneTSC2 in patients with pulmonary lymphangioleiomyomatosis A Astrinidis, L Khare, T Carsillo, T Smolarek, KS Au, H Northrup, ... Journal of medical genetics 37 (1), 55-57, 2000 | 146 | 2000 |
| Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent M Karbowniczek, T Cash, M Cheung, GP Robertson, A Astrinidis, ... Journal of Biological Chemistry 279 (29), 29930-29937, 2004 | 133 | 2004 |
| Cell cycle-regulated phosphorylation of hamartin, the product of the tuberous sclerosis complex 1 gene, by cyclin-dependent kinase 1/cyclin B A Astrinidis, W Senapedis, TR Coleman, EP Henske Journal of Biological Chemistry 278 (51), 51372-51379, 2003 | 100 | 2003 |
| Hamartin, the tuberous sclerosis complex 1 gene product, interacts with polo-like kinase 1 in a phosphorylation-dependent manner A Astrinidis, W Senapedis, EP Henske Human molecular genetics 15 (2), 287-297, 2006 | 94 | 2006 |
| The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth, and chemosensitivity under hypoxic conditions EM Matthew, LS Hart, A Astrinidis, A Navaraj, NG Dolloff, DT Dicker, ... Cell Cycle 8 (24), 4168-4175, 2009 | 83 | 2009 |
| The Ribosomal Protein S19 Suppresses Antitumor Immune Responses via the Complement C5a Receptor 1 MM Markiewski, SK Vadrevu, SK Sharma, NK Chintala, S Ghouse, ... The Journal of Immunology 198 (7), 2989-2999, 2017 | 59 | 2017 |
| TACC3-TSC2 maintains nuclear envelope structure and controls cell division L Gómez-Baldó, S Schmidt, CA Maxwell, N Bonifaci, T Gabaldón, ... Cell Cycle 9 (6), 1143-1155, 2010 | 47 | 2010 |
| Pharmacological inhibition of Polo-like kinase 1 (PLK1) by BI-2536 decreases the viability and survival of hamartin and tuberin deficient cells via induction of apoptosis and … M Valianou, AM Cox, B Pichette, S Hartley, UR Paladhi, A Astrinidis Cell cycle 14 (3), 399-407, 2015 | 37 | 2015 |
| Lymphangioleiomyomatosis KF Xu, W Xu, S Liu, J Yu, X Tian, Y Yang, ST Wang, W Zhang, R Feng, ... Seminars in Respiratory and Critical Care Medicine 41 (02), 256-268, 2020 | 36 | 2020 |
| The transcription factor SP1 regulates centriole function and chromosomal stability through a functional interaction with the mammalian target of rapamycin/raptor complex A Astrinidis, J Kim, CM Kelly, BA Olofsson, B Torabi, EM Sorokina, ... Genes, Chromosomes and Cancer 49 (3), 282-297, 2010 | 34 | 2010 |
| Mutational analysis of TSC1 and TSC2 genes in Tuberous Sclerosis Complex patients from Greece S Avgeris, F Fostira, A Vagena, Y Ninios, A Delimitsou, R Vodicka, R Vrtel, ... Scientific reports 7 (1), 16697, 2017 | 31 | 2017 |
| Aberrant cellular differentiation and migration in renal and pulmonary tuberous sclerosis complex A Astrinidis, EP Henske Journal of child neurology 19 (9), 710-715, 2004 | 27 | 2004 |
| Mitochondrial DNA polymorphism in the Vietnamese population R Ivanova, A Astrinidis, V Lepage, S Djoulah, E Wijnen, AN Vu‐Trieu, ... European journal of immunogenetics 26 (6), 417-422, 1999 | 27 | 1999 |
Elizabeth P HenskeProfessor of Medicine, Harvard Medical SchoolVerified email at bwh.harvard.edu
