| Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation M Muik, I Frischauf, I Derler, M Fahrner, J Bergsmann, P Eder, R Schindl, ... Journal of Biological Chemistry 283 (12), 8014-8022, 2008 | 506 | 2008 |
| A cytosolic homomerization and a modulatory domain within STIM1 C terminus determine coupling to ORAI1 channels M Muik, M Fahrner, I Derler, R Schindl, J Bergsmann, I Frischauf, ... Journal of Biological Chemistry 284 (13), 8421-8426, 2009 | 404 | 2009 |
| STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation M Muik, M Fahrner, R Schindl, P Stathopulos, I Frischauf, I Derler, P Plenk, ... The EMBO journal 30 (9), 1678-1689, 2011 | 291 | 2011 |
| Proliferation of aligned mammalian cells on laser-nanostructured polystyrene E Rebollar, I Frischauf, M Olbrich, T Peterbauer, S Hering, J Preiner, ... Biomaterials 29 (12), 1796-1806, 2008 | 281 | 2008 |
| Novel pyrazole compounds for pharmacological discrimination between receptor‐operated and store‐operated Ca2+ entry pathways H Schleifer, B Doleschal, M Lichtenegger, R Oppenrieder, I Derler, ... British journal of pharmacology 167 (8), 1712-1722, 2012 | 220 | 2012 |
| Molecular determinants of the coupling between STIM1 and Orai channels: differential activation of Orai1–3 channels by a STIM1 coiled-coil mutant I Frischauf, M Muik, I Derler, J Bergsmann, M Fahrner, R Schindl, ... Journal of biological chemistry 284 (32), 21696-21706, 2009 | 195 | 2009 |
| 2-aminoethoxydiphenyl borate alters selectivity of Orai3 channels by increasing their pore size R Schindl, J Bergsmann, I Frischauf, I Derler, M Fahrner, M Muik, R Fritsch, ... Journal of Biological Chemistry 283 (29), 20261-20267, 2008 | 168 | 2008 |
| The STIM/Orai coupling machinery I Frischauf, R Schindl, I Derler, J Bergsmann, M Fahrner, C Romanin Channels 2 (4), 261-268, 2008 | 146 | 2008 |
| Mobile ionic impurities in poly (vinyl alcohol) gate dielectric: possible source of the hysteresis in organic field‐effect transistors M Egginger, M Irimia‐Vladu, R Schwödiauer, A Tanda, I Frischauf, ... Advanced materials 20 (5), 1018-1022, 2008 | 141 | 2008 |
| Resting state Orai1 diffuses as homotetramer in the plasma membrane of live mammalian cells J Madl, J Weghuber, R Fritsch, I Derler, M Fahrner, I Frischauf, B Lackner, ... Journal of Biological Chemistry 285 (52), 41135-41142, 2010 | 126 | 2010 |
| Mechanistic view on domains mediating STIM1–Orai coupling M Fahrner, M Muik, I Derler, R Schindl, R Fritsch, I Frischauf, C Romanin Immunological reviews 231 (1), 99-112, 2009 | 123 | 2009 |
| STIM1 activation of Orai1 V Lunz, C Romanin, I Frischauf Cell calcium 77, 29-38, 2019 | 122 | 2019 |
| Increased hydrophobicity at the N terminus/membrane interface impairs gating of the severe combined immunodeficiency-related ORAI1 mutant I Derler, M Fahrner, O Carugo, M Muik, J Bergsmann, R Schindl, ... Journal of Biological Chemistry 284 (23), 15903-15915, 2009 | 91 | 2009 |
| Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription I Frischauf, M Litviňuková, R Schober, V Zayats, B Svobodová, ... Science signaling 10 (507), eaao0358, 2017 | 86 | 2017 |
| Plasticity in Ca2+ selectivity of Orai1/Orai3 heteromeric channel R Schindl, I Frischauf, J Bergsmann, M Muik, I Derler, B Lackner, ... Proceedings of the National Academy of Sciences 106 (46), 19623-19628, 2009 | 84 | 2009 |
| A calcium-accumulating region, CAR, in the channel Orai1 enhances Ca2+ permeation and SOCE-induced gene transcription I Frischauf, V Zayats, M Deix, A Hochreiter, I Jardin, M Muik, B Lackner, ... Science signaling 8 (408), ra131-ra131, 2015 | 75 | 2015 |
| Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6-mediated Ca2+ influx R Schindl, R Fritsch, I Jardin, I Frischauf, H Kahr, M Muik, MC Riedl, ... Journal of Biological Chemistry 287 (42), 35612-35620, 2012 | 66 | 2012 |
| Cooperativeness of Orai cytosolic domains tunes subtype-specific gating I Frischauf, R Schindl, J Bergsmann, I Derler, M Fahrner, M Muik, R Fritsch, ... Journal of Biological Chemistry 286 (10), 8577-8584, 2011 | 66 | 2011 |
| Communication between N terminus and loop2 tunes Orai activation M Fahrner, SK Pandey, M Muik, L Traxler, C Butorac, M Stadlbauer, ... Journal of Biological Chemistry 293 (4), 1271-1285, 2018 | 60 | 2018 |
| Molecular determinants within N terminus of Orai3 protein that control channel activation and gating J Bergsmann, I Derler, M Muik, I Frischauf, M Fahrner, P Pollheimer, ... Journal of Biological Chemistry 286 (36), 31565-31575, 2011 | 59 | 2011 |
Christoph RomaninProfessor of Biophysics, Johannes Kepler University LinzVerified email at jku.at
