Exosomal miR-21a-5p mediates cardioprotection by mesenchymal stem cells KM Luther, L Haar, M McGuinness, Y Wang, TL Lynch IV, A Phan, Y Song, ... Journal of molecular and cellular cardiology 119, 125-137, 2018 | 177 | 2018 |
Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin CN Toepfer, H Wakimoto, AC Garfinkel, B McDonough, D Liao, J Jiang, ... Science translational medicine 11 (476), eaat1199, 2019 | 174 | 2019 |
Oxidative stress in dilated cardiomyopathy caused by MYBPC3 mutation TL Lynch, M Sivaguru, M Velayutham, AJ Cardounel, M Michels, ... Oxidative medicine and cellular longevity 2015, 2015 | 51 | 2015 |
Cardiac inflammation in genetic dilated cardiomyopathy caused by MYBPC3 mutation TL Lynch IV, MA Ismahil, AG Jegga, MJ Zilliox, C Troidl, SD Prabhu, ... Journal of molecular and cellular cardiology 102, 83-93, 2017 | 49 | 2017 |
Ablation of the calpain-targeted site in cardiac myosin binding protein-C is cardioprotective during ischemia-reperfusion injury DY Barefield, JW McNamara, TL Lynch, DWD Kuster, S Govindan, L Haar, ... Journal of molecular and cellular cardiology 129, 236-246, 2019 | 28 | 2019 |
Altered C10 domain in cardiac myosin binding protein-C results in hypertrophic cardiomyopathy DWD Kuster, TL Lynch IV, DY Barefield, M Sivaguru, G Kuffel, MJ Zilliox, ... Cardiovascular research 115 (14), 1986-1997, 2019 | 24 | 2019 |
Alterations in multi‐scale cardiac architecture in association with phosphorylation of myosin binding protein‐C EN Taylor, MP Hoffman, DY Barefield, GE Aninwene, AD Abrishamchi, ... Journal of the American Heart Association 5 (3), e002836, 2016 | 24 | 2016 |
N-terminal fragment of cardiac myosin binding protein-C triggers pro-inflammatory responses in vitro C Lipps, JH Nguyen, L Pyttel, TL Lynch IV, C Liebetrau, G Aleshcheva, ... Journal of molecular and cellular cardiology 99, 47-56, 2016 | 21 | 2016 |
Surviving the infarct: A profile of cardiac myosin binding protein‐C pathogenicity, diagnostic utility, and proteomics in the ischemic myocardium TL Lynch, S Sadayappan PROTEOMICS–Clinical Applications 8 (7-8), 569-577, 2014 | 21 | 2014 |
Cardioprotection via the skin: nociceptor-induced conditioning against cardiac MI in the NIC of time X Ren, AE Roessler, TL Lynch 4th, L Haar, F Mallick, Y Lui, M Tranter, ... American Journal of Physiology-Heart and Circulatory Physiology 316 (3 …, 2019 | 18 | 2019 |
Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility TL Lynch IV, M Kumar, JW McNamara, DWD Kuster, M Sivaguru, ... Journal of molecular and cellular cardiology 156, 33-44, 2021 | 17 | 2021 |
Acting on an impulse (or two): Advantages of high-frequency tetanic onset in skeletal muscle RL Moss, TL Lynch IV, DP Fitzsimons Journal of General Physiology 149 (3), 297-300, 2017 | 6 | 2017 |
Cardiac myosin binding protein-C autoantibodies are potential early indicators of cardiac dysfunction and patient outcome in acute coronary syndrome TL Lynch IV, DWD Kuster, B Gonzalez, N Balasubramanian, N Nair, ... Basic to Translational Science 2 (2), 122-131, 2017 | 5 | 2017 |
High-throughput diagnostic assay for a highly prevalent cardiomyopathy-associated mybpc3 variant DY Barefield, TL Lynch IV, A Jagadeesan, T Sanagala, S Sadayappan Journal of molecular biomarkers & diagnosis 7 (6), 2016 | 5 | 2016 |
MYBPC3 Mutations cause Hypertrophic Cardiomyopathy by Dysregulating Myosin: Implications for Therapy CN Toepfer, H Wakimoto, AC Garfinkel, B McDonough, D Liao, J Jiang, ... bioRxiv, 304204, 2018 | 4 | 2018 |
Protein kinase C‐site phosphorylation of cardiac myosin binding protein‐C decreases cross‐bridge kinetics (1081.5) S Govindan, Y Ait Mou, T Lynch, P de Tombe, S Sadayappan The FASEB Journal 28, 1081.5, 2014 | 2 | 2014 |
Fast skeletal myosin binding protein-C expression exacerbates dysfunction in heart failure J McNamara, T Song, P Alam, A Binek, R Singh, M Nieman, S Koch, ... bioRxiv, 2024.04. 30.591979, 2024 | | 2024 |
Abstract MP219: Hnrnpa2b1-dependent Selective Sorting Of Mir-486a-5p Into Msc-derived Exosomes Contributes To Cardioprotection K Jones, A Phan, C Zhang, L Haar, T Lynch Circulation Research 129 (Suppl_1), AMP219-AMP219, 2021 | | 2021 |
Identification of RNA-binding Proteins Facilitating microRNA Sorting into Extracellular Vesicles AP Phan, T Lynch, M Cabe, WK Jones | | 2020 |
MiR‐486a‐5p Exerts Cardioprotection Against Ischemia Repefusion via Suppression of PDCD4 A Phan, T Lynch IV, M McGuinness, WK Jones The FASEB Journal 33 (S1), 676.5-676.5, 2019 | | 2019 |