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Ruben Carrasco
Ruben Carrasco
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Verified email at partners.org
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Cited by
Cited by
Year
International Myeloma Working Group molecular classification of multiple myeloma: spotlight review
R Fonseca, PL Bergsagel, J Drach, J Shaughnessy, N Gutierrez, ...
Leukemia 23 (12), 2210-2221, 2009
11812009
A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance
D Chauhan, Z Tian, B Nicholson, KGS Kumar, B Zhou, R Carrasco, ...
Cancer cell 22 (3), 345-358, 2012
5632012
Class IIa HDAC inhibition reduces breast tumours and metastases through anti-tumour macrophages
JL Guerriero, A Sotayo, HE Ponichtera, JA Castrillon, AL Pourzia, ...
Nature 543 (7645), 428-432, 2017
4822017
Bortezomib induces canonical nuclear factor-κB activation in multiple myeloma cells
T Hideshima, H Ikeda, D Chauhan, Y Okawa, N Raje, K Podar, ...
Blood, The Journal of the American Society of Hematology 114 (5), 1046-1052, 2009
4452009
Constitutive telomerase expression promotes mammary carcinomas in aging mice
SE Artandi, S Alson, MK Tietze, NE Sharpless, S Ye, RA Greenberg, ...
Proceedings of the National Academy of Sciences 99 (12), 8191-8196, 2002
3942002
Pathogenesis of myeloma
KC Anderson, RD Carrasco
Annual Review of Pathology: Mechanisms of Disease 6, 249-274, 2011
3712011
Relative mitochondrial priming of myeloblasts and normal HSCs determines chemotherapeutic success in AML
TT Vo, J Ryan, R Carrasco, D Neuberg, DJ Rossi, RM Stone, ...
Cell 151 (2), 344-355, 2012
3662012
Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features
AK Azab, J Hu, P Quang, F Azab, C Pitsillides, R Awwad, B Thompson, ...
Blood, The Journal of the American Society of Hematology 119 (24), 5782-5794, 2012
3492012
A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance
Z Tian, P D’Arcy, X Wang, A Ray, YT Tai, Y Hu, RD Carrasco, ...
Blood, The Journal of the American Society of Hematology 123 (5), 706-716, 2014
3302014
Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers
F Cottini, T Hideshima, C Xu, M Sattler, M Dori, L Agnelli, E Ten Hacken, ...
Nature medicine 20 (6), 599-606, 2014
3142014
A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma
G Görgün, E Calabrese, T Hideshima, J Ecsedy, G Perrone, M Mani, ...
Blood, The Journal of the American Society of Hematology 115 (25), 5202-5213, 2010
3092010
Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: a therapeutic target
D Chauhan, AV Singh, M Brahmandam, R Carrasco, M Bandi, ...
Cancer cell 16 (4), 309-323, 2009
2962009
Transaminase inhibition by 2-hydroxyglutarate impairs glutamate biosynthesis and redox homeostasis in glioma
SK McBrayer, JR Mayers, GJ DiNatale, DD Shi, J Khanal, AA Chakraborty, ...
Cell 175 (1), 101-116. e25, 2018
2732018
miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/β-catenin/BCL9 pathway
JJ Zhao, J Lin, D Zhu, X Wang, D Brooks, M Chen, ZB Chu, K Takada, ...
Cancer research 74 (6), 1801-1813, 2014
2022014
The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia
X Leleu, X Jia, J Runnels, HT Ngo, AS Moreau, M Farag, JA Spencer, ...
Blood, The Journal of the American Society of Hematology 110 (13), 4417-4426, 2007
1722007
Clonal architecture of CXCR4 WHIM‐like mutations in Waldenström Macroglobulinaemia
L Xu, ZR Hunter, N Tsakmaklis, Y Cao, G Yang, J Chen, X Liu, S Kanan, ...
British journal of haematology 172 (5), 735-744, 2016
1432016
P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment
AK Azab, P Quang, F Azab, C Pitsillides, B Thompson, T Chonghaile, ...
Blood, The Journal of the American Society of Hematology 119 (6), 1468-1478, 2012
1302012
Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma
T Hideshima, J Qi, RM Paranal, W Tang, E Greenberg, N West, ...
Proceedings of the National Academy of Sciences 113 (46), 13162-13167, 2016
1252016
Nanoparticles for immune cytokine TRAIL-based cancer therapy
PPG Guimarães, S Gaglione, T Sewastianik, RD Carrasco, R Langer, ...
ACS nano 12 (2), 912-931, 2018
1212018
The Cyclophilin A–CD147 complex promotes the proliferation and homing of multiple myeloma cells
DI Zhu, Z Wang, JJ Zhao, T Calimeri, J Meng, T Hideshima, M Fulciniti, ...
Nature medicine 21 (6), 572-580, 2015
1062015
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