De novo design of protein structure and function with RFdiffusion JL Watson, D Juergens, NR Bennett, BL Trippe, J Yim, HE Eisenach, ... Nature 620 (7976), 1089-1100, 2023 | 1063* | 2023 |
Robust deep learning–based protein sequence design using ProteinMPNN J Dauparas, I Anishchenko, N Bennett, H Bai, RJ Ragotte, LF Milles, ... Science 378 (6615), 49-56, 2022 | 963 | 2022 |
Scaffolding protein functional sites using deep learning J Wang, S Lisanza, D Juergens, D Tischer, JL Watson, KM Castro, ... Science 377 (6604), 387-394, 2022 | 327 | 2022 |
Hallucinating symmetric protein assemblies BIM Wicky, LF Milles, A Courbet, RJ Ragotte, J Dauparas, E Kinfu, S Tipps, ... Science 378 (6615), 56-61, 2022 | 167 | 2022 |
JAK1 gain-of-function causes an autosomal dominant immune dysregulatory and hypereosinophilic syndrome KL Del Bel, RJ Ragotte, A Saferali, S Lee, SM Vercauteren, SA Mostafavi, ... Journal of Allergy and Clinical Immunology 139 (6), 2016-2020. e5, 2017 | 142 | 2017 |
The RH5-CyRPA-Ripr complex as a malaria vaccine target RJ Ragotte, MK Higgins, SJ Draper Trends in parasitology 36 (6), 545-559, 2020 | 71 | 2020 |
The importance of considering monogenic causes of autoimmunity: A somatic mutation in KRAS causing pediatric Rosai-Dorfman syndrome and systemic lupus erythematosus RJ Ragotte, A Dhanrajani, J Pleydell-Pearce, KL Del Bel, ... Clinical immunology 175, 143-146, 2017 | 54 | 2017 |
Human Basigin (CD147) Does Not Directly Interact with SARS-CoV-2 Spike Glycoprotein RJ Ragotte, D Pulido, FR Donnellan, ML Hill, G Gorini, H Davies, J Brun, ... mSphere 6 (4), e0064721, 2021 | 48* | 2021 |
Atomically accurate de novo design of single-domain antibodies NR Bennett, JL Watson, RJ Ragotte, AJ Borst, DL See, C Weidle, ... bioRxiv, 2024 | 47 | 2024 |
Heterotypic interactions drive antibody synergy against a malaria vaccine candidate RJ Ragotte, D Pulido, AM Lias, D Quinkert, DGW Alanine, A Jamwal, ... Nature communications 13 (1), 933, 2022 | 34 | 2022 |
A systematic review and meta-analysis of patient data from the west Africa (2013–16) Ebola virus disease epidemic AM Rojek, A Salam, RJ Ragotte, E Liddiard, A Elhussain, A Carlqvist, ... Clinical Microbiology and Infection 25 (11), 1307-1314, 2019 | 24 | 2019 |
The PfRCR complex bridges malaria parasite and erythrocyte during invasion B Farrell, N Alam, MN Hart, A Jamwal, RJ Ragotte, H Walters-Morgan, ... Nature 625 (7995), 578-584, 2024 | 13 | 2024 |
Human JAK1 gain of function causes dysregulated myelopoeisis and severe allergic inflammation CM Biggs, A Cordeiro-Santanach, SV Prykhozhij, AP Deveau, Y Lin, ... JCI insight 7 (24), 2022 | 12 | 2022 |
Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex BG Williams, LDW King, D Pulido, D Quinkert, AM Lias, SE Silk, ... Nature Communications 15 (1), 4857, 2024 | 7 | 2024 |
The dual action of human antibodies specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking invasion and inactivating extracellular merozoites GE Weiss, RJ Ragotte, D Quinkert, AM Lias, MG Dans, C Boulet, O Looker, ... PLoS Pathogens 19 (9), e1011182, 2023 | 5 | 2023 |
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists M Glögl, A Krishnakumar, RJ Ragotte, I Goreshnik, B Coventry, AK Bera, ... Science 386 (6726), 1154-1161, 2024 | 3 | 2024 |
Idiopathic splenomegaly in childhood and the spectrum of RAS-associated lymphoproliferative disease: a case report G Blanchard-Rohner, RJ Ragotte, AK Junker, M Sharma, KL Del Bel, ... BMC pediatrics 21, 1-4, 2021 | 3 | 2021 |
Structure of the PfRCR complex which bridges the malaria parasite and erythrocyte during invasion B Farrell, N Alam, MN Hart, A Jamwal, RJ Ragotte, H Walters-Morgan, ... bioRxiv, 2023.01. 30.526221, 2023 | 2 | 2023 |
De novo designed proteins neutralize lethal snake venom toxins SV Torres, MB Valle, SP Mackessy, SK Menzies, NR Casewell, S Ahmadi, ... Research Square, rs. 3. rs-4402792, 2024 | 1 | 2024 |
De novo designed proteins neutralize lethal snake venom toxins D Baker, SV Torres, MB Valle, S Mackessy, S Menzies, N Casewell, ... | 1 | 2024 |