Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance V Barbier, J Erbani, C Fiveash, JM Davies, J Tay, MR Tallack, J Lowe, ... Nature communications 11 (1), 2042, 2020 | 160 | 2020 |
Evidence for a dual function of EphB4 as tumor promoter and suppressor regulated by the absence or presence of the ephrin‐B2 ligand R Rutkowski, I Mertens‐Walker, JE Lisle, AC Herington, SA Stephenson International journal of cancer 131 (5), 2012 | 75 | 2012 |
Eph receptors and their ligands: promising molecular biomarkers and therapeutic targets in prostate cancer JE Lisle, I Mertens-Walker, R Rutkowski, AC Herington, SA Stephenson Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1835 (2), 243-257, 2013 | 51 | 2013 |
Anti-tumour effects of antibodies targeting the extracellular cysteine-rich region of the receptor tyrosine kinase EphB4 SA Stephenson, EL Douglas, I Mertens-Walker, JE Lisle, MSN Maharaj, ... Oncotarget 6 (10), 7554, 2015 | 34 | 2015 |
Murine, but not human, ephrin-B2 can be efficiently cleaved by the serine protease kallikrein-4: implications for xenograft models of human prostate cancer JE Lisle, I Mertens-Walker, CR Stephens, SH Stansfield, JA Clements, ... Experimental Cell Research 333 (1), 136-146, 2015 | 15 | 2015 |
Activation of membrane-bound proteins and receptor systems: a link between tissue kallikrein and the KLK-related peptidases Y Dong, BS Harrington, MN Adams, A Wortmann, SA Stephenson, J Lisle, ... Biological Chemistry 395 (9), 977-990, 2014 | 13 | 2014 |
EphB4 localises to the nucleus of prostate cancer cells I Mertens-Walker, JE Lisle, WA Nyberg, CR Stephens, L Burke, ... Experimental Cell Research 333 (1), 105-115, 2015 | 9 | 2015 |
Development of a gene edited next-generation hematopoietic cell transplant to enable acute myeloid leukemia treatment by solving off-tumor toxicity JR Lydeard, MI Lin, HG Ge, A Halfond, S Wang, MB Jones, J Etchin, ... Molecular Therapy-Methods & Clinical Development 31, 2023 | 8 | 2023 |
Inhibiting Eph kinase activity may not be “Eph” ective for cancer treatment AC Herington, I Mertens-Walker, JE Lisle, M Maharaj, SA Stephenson Growth Factors 32 (6), 207-213, 2014 | 6 | 2014 |
Knock out of CD123 or CLL-1 By CRISPR-Cas9 Editing from Human Hematopoietic Stem Cell Transplants Provide New Possibilities for Increasing Therapeutic Index and Safety for AML … C Luo, G Angelini, S Krishnamurthy, J Lisle, M Isik, A Ghdossi, ... Blood 138, 3818, 2021 | 1 | 2021 |
Cell-Extrinsic Differentiation Block Mediated by EphA3 in Pre-Leukaemic Thymus Contributes to Disease Progression AC Pliego Zamora, H Ranasinghe, JE Lisle, CK Ng, S Huang, R Wadlow, ... Cancers 13 (15), 3858, 2021 | 1 | 2021 |
Compositions and methods for cd123 modification J Lydeard, C Luo, M Lin, BP Mishra, JE Lisle US Patent App. 18/023,561, 2024 | | 2024 |
Compositions and methods for cll1 modification J Lydeard, C Luo, M Lin, JE Lisle US Patent App. 18/023,548, 2024 | | 2024 |
CD33-Deleted Hematopoietic Cells (Trem-Cel) Are Protected from CD33xCD3 Bispecific Antibody Treatment and Produce Significantly Reduced Levels of Inflammatory Cytokines in … J Lisle, S Krishnamurthy, A Halfond, L Pechilis, N Manalo, M Chng, ... Blood 142, 3425, 2023 | | 2023 |
Multiplex Engineering of Human CD34+ HSPCs Enables Dual Gene Knock-out While Maintaining High Engraftment Potential and Safety N Patel, M Pettiglio, C Cummins, J Pimentel, A Kapuria, A Ghodssi, M Isik, ... Blood 138, 2939, 2021 | | 2021 |
EPHA3 IS DISPENSABLE FOR NUP98-HOXD13-DRIVEN ACUTE MYELOID LEUKAEMIA BUT CRITICAL FOR NORMAL HAEMATOPOIETIC STEM CELL FUNCTION C Slape, J Lisle, AP Zamora, R Wadlow, S Huang Experimental Hematology 76, S85, 2019 | | 2019 |
CELL-EXTRINSIC EFFECTS IN T CELL PRE-LEUKEMIA STEM CELLS AP Zamora, H Ranasinghe, J Lisle, S Huang, C Slape Experimental Hematology 76, S82, 2019 | | 2019 |
Serial Transplantation of Pre-Leukemic T-ALL Stem Cells Requires EphA3 AP Zamora, H Ranasinghe, J Lisle, C Slape Experimental Hematology 64, S104, 2018 | | 2018 |
Variation in HoxA9 Expression in the NUP98-HOXD13 Myelodysplasia Model, Using a Novel HoxA9-eGFP Reporter Mouse C Slape, AP Zamora, J Lisle, J Huang, L Zhao, P Koopman Experimental Hematology 64, S104, 2018 | | 2018 |
Proteolysis of ephb4 in prostate cancer produces a bioactive intracellular domain fragment A Herington, J Lisle, I Mertens-Walker, C Stephens, J Clements, ... CLINICAL ENDOCRINOLOGY 86, 38-38, 2017 | | 2017 |