Brian M. Baker
Brian M. Baker
Department of Chemistry & Biochemistry, University of Notre Dame
Verified email at - Homepage
Cited by
Cited by
Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical
YH Ding, BM Baker, DN Garboczi, WE Biddison, DC Wiley
Immunity 11 (1), 45-56, 1999
Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity
F Duan, J Duitama, S Al Seesi, CM Ayres, SA Corcelli, AP Pawashe, ...
Journal of Experimental Medicine 211 (11), 2231-2248, 2014
Evaluation of linked protonation effects in protein binding reactions using isothermal titration calorimetry
BM Baker, KP Murphy
Biophysical journal 71 (4), 2049-2055, 1996
T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility
OY Borbulevych, KH Piepenbrink, BE Gloor, DR Scott, RF Sommese, ...
Immunity 31 (6), 885-896, 2009
Dissecting the energetics of a protein-protein interaction: the binding of ovomucoid third domain to elastase
BM Baker, KP Murphy
Journal of molecular biology 268 (2), 557-569, 1997
The structure and stability of an HLA-A* 0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site
AR Khan, BM Baker, P Ghosh, WE Biddison, DC Wiley
The Journal of Immunology 164 (12), 6398, 2000
Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling
BM Baker, SJ Gagnon, WE Biddison, DC Wiley
Immunity 13 (4), 475-484, 2000
Prediction of binding energetics from structure using empirical parameterization
BM Baker, KP Murphy
Methods in enzymology 295, 294-315, 1998
TCRs used in cancer gene therapy cross-react with MART-1/Melan-A tumor antigens via distinct mechanisms
OY Borbulevych, SM Santhanagopolan, M Hossain, BM Baker
The Journal of Immunology 187 (5), 2453-2463, 2011
Conformational changes and flexibility in T-cell receptor recognition of peptide–MHC complexes
KM Armstrong, KH Piepenbrink, BM Baker
Biochemical Journal 415 (Pt 2), 183, 2008
Poor immunogenicity of a self/tumor antigen derives from peptide-MHC-I instability and is independent of tolerance
Z Yu, MR Theoret, CE Touloukian, DR Surman, SC Garman, ...
Journal of Clinical Investigation 114, 551-559, 2004
Increased immunogenicity of an anchor-modified tumor-associated antigen is due to the enhanced stability of the peptide/MHC complex: implications for vaccine design
OY Borbulevych, TK Baxter, Z Yu, NP Restifo, BM Baker
The Journal of Immunology 174 (8), 4812, 2005
Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity
JJ Adams, S Narayanan, ME Birnbaum, SS Sidhu, SJ Blevins, MH Gee, ...
Nature immunology, 2015
Two different T cell receptors use different thermodynamic strategies to recognize the same peptide/MHC ligand
RL Davis-Harrison, KM Armstrong, BM Baker
Journal of molecular biology 346 (2), 533-550, 2005
Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition
OY Borbulevych, FK Insaidoo, TK Baxter, DJ Powell Jr, LA Johnson, ...
Journal of molecular biology 372 (5), 1123-1136, 2007
Interactions between CLIP-170, tubulin, and microtubules: implications for the mechanism of Clip-170 plus-end tracking behavior
ES Folker, BM Baker, HV Goodson
Molecular biology of the cell 16 (11), 5373-5384, 2005
Prediction of neo-epitope immunogenicity reveals TCR recognition determinants and provides insight into immunoediting
J Schmidt, AR Smith, M Magnin, J Racle, JR Devlin, S Bobisse, J Cesbron, ...
Cell Reports Medicine 2 (2), 2021
Identification of a Crucial Energetic Footprint on the α1 Helix of Human Histocompatibility Leukocyte Antigen (Hla)-A2 That Provides Functional Interactions for Recognition by …
BM Baker, RV Turner, SJ Gagnon, DC Wiley, WE Biddison
The Journal of experimental medicine 193 (5), 551, 2001
Emerging Concepts in TCR Specificity: Rationalizing and (Maybe) Predicting Outcomes
NK Singh, TP Riley, SCB Baker, T Borrman, Z Weng, BM Baker
The Journal of Immunology 199 (7), 2203-2213, 2017
Structural and dynamic control of T‐cell receptor specificity, cross‐reactivity, and binding mechanism
BM Baker, DR Scott, SJ Blevins, WF Hawse
Immunological Reviews 250 (1), 10-31, 2012
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