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Ehesan Sharif
Ehesan Sharif
Principal Investigator, Arcus Biosciences
Verified email at arcusbio.com
Title
Cited by
Cited by
Year
Total synthesis of jadomycin A and a carbasugar analogue of jadomycin B
M Shan, EU Sharif, GA O'Doherty
Angewandte Chemie International Edition 49 (49), 9492-9495, 2010
882010
De novo asymmetric synthesis of the mezzettiaside family of natural products via the iterative use of a dual B-/Pd-catalyzed glycosylation
GA áO'Doherty
Chemical Science 5 (6), 2230-2234, 2014
832014
Discovery of AB680: a potent and selective inhibitor of CD73
KV Lawson, J Kalisiak, EA Lindsey, ET Newcomb, MR Leleti, L Debien, ...
Journal of Medicinal Chemistry 63 (20), 11448-11468, 2020
592020
Merremoside D: De Novo Synthesis of the Purported Structure, NMR Analysis, and Comparison of Spectral Data
EU Sharif, HYL Wang, NG Akhmedov, GA O’Doherty
Organic letters 16 (2), 492-495, 2014
442014
C3′/C4′‐Stereochemical Effects of Digitoxigenin α‐L‐/α‐D‐Glycoside in Cancer Cytotoxicity
JW Hinds, SB McKenna, EU Sharif, HYL Wang, NG Akhmedov, ...
ChemMedChem 8 (1), 63-69, 2013
352013
Biosynthesis and total synthesis studies on the jadomycin family of natural products
EU Sharif, GA O'Doherty
European journal of organic chemistry 2012 (11), 2095-2108, 2012
342012
Discovery of potent and selective PI3Kγ inhibitors
SL Drew, R Thomas-Tran, JW Beatty, J Fournier, KV Lawson, DH Miles, ...
Journal of Medicinal Chemistry 63 (19), 11235-11257, 2020
322020
Roles of the Synergistic Reductive O-Methyltransferase GilM and of O-Methyltransferase GilMT in the Gilvocarcin Biosynthetic Pathway
N Tibrewal, TE Downey, SG Van Lanen, E Ul Sharif, GA O’Doherty, ...
Journal of the American Chemical Society 134 (30), 12402-12405, 2012
292012
New catalytic asymmetric formation of oxygen heterocycles bearing nucleoside bases at the anomeric carbon
BM Trost, S Xu, EU Sharif
Journal of the American Chemical Society 141 (26), 10199-10204, 2019
202019
Discovery of Potent and Selective Methylenephosphonic Acid CD73 Inhibitors
EU Sharif, J Kalisiak, KV Lawson, DH Miles, E Newcomb, EA Lindsey, ...
Journal of Medicinal Chemistry, 2021
192021
Modulators of 5′-nucleotidase, ecto and the use thereof
LPP Debien, JC Jaen, J Kalisiak, KV Lawson, MR Leleti, EA Lindsey, ...
US Patent 10,239,912, 2019
182019
Discovery of potent and selective 7-azaindole isoindolinone-based PI3Kγ inhibitors
DH Miles, X Yan, R Thomas-Tran, J Fournier, EU Sharif, SL Drew, G Mata, ...
ACS Medicinal Chemistry Letters 11 (11), 2244-2252, 2020
152020
Combining adenosine receptor inhibition with AB928 and chemotherapy results in greater immune activation and tumor control
MJ Walters, D Piovesan, J Tan, D DiRenzo, F Yin, D Miles, MR Leleti, ...
Cancer Research 78 (13_Supplement), 5556-5556, 2018
152018
Modulators of 5′-nucleotidase, ecto and the use thereof
LPP Debien, JC Jaen, J Kalisiak, KV Lawson, MR Leleti, EA Lindsey, ...
US Patent 10,981,944, 2021
132021
Characterization of the potent and selective A2aR antagonist AB928 for the treatment of cancer
MJ Walters, JB Tan, A Becker, F Yi, T Park, MR Leleti, B Rosen, E Sharif, ...
Cancer Research 77 (13_Supplement), 4572-4572, 2017
112017
Azolopyrimidine for the treatment of cancer-related disorders
J Beatty, L Debien, J Jeffrey, MR Leleti, D Mandal, D Miles, J Powers, ...
US Patent 10,399,962, 2019
102019
Design, synthesis, and structure–activity relationship optimization of pyrazolopyrimidine amide inhibitors of phosphoinositide 3-kinase γ (PI3Kγ)
G Mata, DH Miles, SL Drew, J Fournier, KV Lawson, AK Mailyan, ...
Journal of Medicinal Chemistry 65 (2), 1418-1444, 2021
92021
Ruthenium‐Catalyzed Multicomponent Reactions: Access to α‐Silyl‐β‐Hydroxy Vinylsilanes, Stereodefined 1, 3‐Dienes, and Cyclohexenes
BM Trost, DC Koester, EU Sharif
Chemistry–A European Journal 22 (8), 2634-2638, 2016
92016
Regioselective bromination: an approach to the D-ring of the gilvocarcins
EU Sharif, GA O’Doherty
Heterocycles 88, 1275-1285, 2014
82014
Abstract A162: AB928, a dual antagonist of the A2aR and A2bR adenosine receptors, relieves adenosine-mediated immune suppression
D DiRenzo, D Piovesan, J Tan, DH Miles, MR Leleti, T Park, F Soriano, ...
Cancer Immunology Research 7 (2_Supplement), A162-A162, 2019
72019
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