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Year
Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis
K Pethe, P Bifani, J Jang, S Kang, S Park, S Ahn, J Jiricek, J Jung, ...
Nature medicine 19 (9), 1157-1160, 2013
6282013
An immune-responsive Serpin regulates the melanization cascade in Drosophila
E De Gregorio, SJ Han, WJ Lee, MJ Baek, T Osaki, SI Kawabata, BL Lee, ...
Developmental cell 3 (4), 581-592, 2002
4142002
Gram-negative bacteria-binding protein, a pattern recognition receptor for lipopolysaccharide and β-1, 3-glucan that mediates the signaling for the induction of innate immune …
YS Kim, JH Ryu, SJ Han, KH Choi, KB Nam, IH Jang, B Lemaitre, PT Brey, ...
Journal of Biological Chemistry 275 (42), 32721-32727, 2000
4112000
A critical role for β cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo
D Gautam, SJ Han, FF Hamdan, J Jeon, B Li, JH Li, Y Cui, D Mears, H Lu, ...
Cell metabolism 3 (6), 449-461, 2006
3452006
Lipocalin-2 induces cardiomyocyte apoptosis by increasing intracellular iron accumulation
G Xu, JH Ahn, SY Chang, M Eguchi, A Ogier, SJ Han, YS Park, CY Shim, ...
Journal of Biological Chemistry 287 (7), 4808-4817, 2012
1492012
Molecular Cloning and Characterization of aDrosophila p38 Mitogen-activated Protein Kinase
SJ Han, KY Choi, PT Brey, WJ Lee
Journal of Biological Chemistry 273 (1), 369-374, 1998
1281998
Genomic structure and ecdysone regulation of the prophenoloxidase 1 gene in the malaria vector Anopheles gambiae
A Ahmed, D Martin, AGO Manetti, SJ Han, WJ Lee, KD Mathiopoulos, ...
Proceedings of the National Academy of Sciences 96 (26), 14795-14800, 1999
1101999
Conformational changes involved in G-protein-coupled-receptor activation
J Wess, SJ Han, SK Kim, KA Jacobson, JH Li
Trends in pharmacological sciences 29 (12), 616-625, 2008
1032008
Role of the M3 muscarinic acetylcholine receptor in β‐cell function and glucose homeostasis
D Gautam, SJ Han, A Duttaroy, D Mears, FF Hamdan, JH Li, Y Cui, J Jeon, ...
Diabetes, Obesity and Metabolism 9, 158-169, 2007
972007
A novel 3, 4-dihydropyrimidin-2 (1H)-one: HIV-1 replication inhibitors with improved metabolic stability
J Kim, T Ok, C Park, W So, M Jo, Y Kim, M Seo, D Lee, S Jo, Y Ko, I Choi, ...
Bioorganic & medicinal chemistry letters 22 (7), 2522-2526, 2012
722012
Analogous Mechanisms of Resistance to Benzothiazinones and Dinitrobenzamides in Mycobacterium smegmatis
AL de Jesus Lopes Ribeiro, G Degiacomi, F Ewann, S Buroni, ...
PloS one 6 (11), e26675, 2011
702011
Identification of an agonist-induced conformational change occurring adjacent to the ligand-binding pocket of the M3 muscarinic acetylcholine receptor
SJ Han, FF Hamdan, SK Kim, KA Jacobson, LM Bloodworth, B Li, J Wess
Journal of Biological Chemistry 280 (41), 34849-34858, 2005
682005
Metabolic Roles of the M3 Muscarinic Acetylcholine Receptor Studied with M3 Receptor Mutant Mice: A Review
D Gautam, J Jeon, JH Li, SJ Han, FF Hamdan, Y Cui, H Lu, C Deng, ...
Journal of Receptors and Signal Transduction 28 (1-2), 93-108, 2008
662008
Cholinergic Stimulation of Amylase Secretion from Pancreatic Acinar Cells Studied with Muscarinic Acetylcholine Receptor Mutant Mice
D Gautam, SJ Han, TS Heard, Y Cui, G Miller, L Bloodworth, J Wess
Journal of Pharmacology and Experimental Therapeutics 313 (3), 995-1002, 2005
652005
Discovery of 3, 4-dihydropyrimidin-2 (1H)-ones with inhibitory activity against HIV-1 replication
J Kim, C Park, T Ok, W So, M Jo, M Seo, Y Kim, JH Sohn, Y Park, MK Ju, ...
Bioorganic & medicinal chemistry letters 22 (5), 2119-2124, 2012
622012
The endogenous siRNA pathway in Drosophila impacts stress resistance and lifespan by regulating metabolic homeostasis
DH Lim, CT Oh, L Lee, JS Hong, SH Noh, S Hwang, S Kim, SJ Han, ...
FEBS letters 585 (19), 3079-3085, 2011
612011
Hepatic muscarinic acetylcholine receptors are not critically involved in maintaining glucose homeostasis in mice
JH Li, D Gautam, SJ Han, JM Guettier, Y Cui, H Lu, C Deng, J O'Hare, ...
Diabetes 58 (12), 2776-2787, 2009
602009
In situ Visualization of Gene Expression Using Polymer‐Coated Quantum–Dot–DNA Conjugates
Y Choi, HP Kim, SM Hong, JY Ryu, SJ Han, R Song
Small 5 (18), 2085-2091, 2009
592009
Distinct structural changes in a G protein-coupled receptor caused by different classes of agonist ligands
JH Li, SJ Han, FF Hamdan, SK Kim, KA Jacobson, LM Bloodworth, ...
Journal of Biological Chemistry 282 (36), 26284-26293, 2007
592007
Lipopolysaccharide-activated kinase, an essential component for the induction of the antimicrobial peptide genes inDrosophila melanogaster cells
YS Kim, SJ Han, JH Ryu, KH Choi, YS Hong, YH Chung, S Perrot, ...
Journal of Biological Chemistry 275 (3), 2071-2079, 2000
572000
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