Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis K Pethe, P Bifani, J Jang, S Kang, S Park, S Ahn, J Jiricek, J Jung, ... Nature medicine 19 (9), 1157-1160, 2013 | 628 | 2013 |
An immune-responsive Serpin regulates the melanization cascade in Drosophila E De Gregorio, SJ Han, WJ Lee, MJ Baek, T Osaki, SI Kawabata, BL Lee, ... Developmental cell 3 (4), 581-592, 2002 | 414 | 2002 |
Gram-negative bacteria-binding protein, a pattern recognition receptor for lipopolysaccharide and β-1, 3-glucan that mediates the signaling for the induction of innate immune … YS Kim, JH Ryu, SJ Han, KH Choi, KB Nam, IH Jang, B Lemaitre, PT Brey, ... Journal of Biological Chemistry 275 (42), 32721-32727, 2000 | 411 | 2000 |
A critical role for β cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo D Gautam, SJ Han, FF Hamdan, J Jeon, B Li, JH Li, Y Cui, D Mears, H Lu, ... Cell metabolism 3 (6), 449-461, 2006 | 345 | 2006 |
Lipocalin-2 induces cardiomyocyte apoptosis by increasing intracellular iron accumulation G Xu, JH Ahn, SY Chang, M Eguchi, A Ogier, SJ Han, YS Park, CY Shim, ... Journal of Biological Chemistry 287 (7), 4808-4817, 2012 | 149 | 2012 |
Molecular Cloning and Characterization of aDrosophila p38 Mitogen-activated Protein Kinase SJ Han, KY Choi, PT Brey, WJ Lee Journal of Biological Chemistry 273 (1), 369-374, 1998 | 128 | 1998 |
Genomic structure and ecdysone regulation of the prophenoloxidase 1 gene in the malaria vector Anopheles gambiae A Ahmed, D Martin, AGO Manetti, SJ Han, WJ Lee, KD Mathiopoulos, ... Proceedings of the National Academy of Sciences 96 (26), 14795-14800, 1999 | 110 | 1999 |
Conformational changes involved in G-protein-coupled-receptor activation J Wess, SJ Han, SK Kim, KA Jacobson, JH Li Trends in pharmacological sciences 29 (12), 616-625, 2008 | 103 | 2008 |
Role of the M3 muscarinic acetylcholine receptor in β‐cell function and glucose homeostasis D Gautam, SJ Han, A Duttaroy, D Mears, FF Hamdan, JH Li, Y Cui, J Jeon, ... Diabetes, Obesity and Metabolism 9, 158-169, 2007 | 97 | 2007 |
A novel 3, 4-dihydropyrimidin-2 (1H)-one: HIV-1 replication inhibitors with improved metabolic stability J Kim, T Ok, C Park, W So, M Jo, Y Kim, M Seo, D Lee, S Jo, Y Ko, I Choi, ... Bioorganic & medicinal chemistry letters 22 (7), 2522-2526, 2012 | 72 | 2012 |
Analogous Mechanisms of Resistance to Benzothiazinones and Dinitrobenzamides in Mycobacterium smegmatis AL de Jesus Lopes Ribeiro, G Degiacomi, F Ewann, S Buroni, ... PloS one 6 (11), e26675, 2011 | 70 | 2011 |
Identification of an agonist-induced conformational change occurring adjacent to the ligand-binding pocket of the M3 muscarinic acetylcholine receptor SJ Han, FF Hamdan, SK Kim, KA Jacobson, LM Bloodworth, B Li, J Wess Journal of Biological Chemistry 280 (41), 34849-34858, 2005 | 68 | 2005 |
Metabolic Roles of the M3 Muscarinic Acetylcholine Receptor Studied with M3 Receptor Mutant Mice: A Review D Gautam, J Jeon, JH Li, SJ Han, FF Hamdan, Y Cui, H Lu, C Deng, ... Journal of Receptors and Signal Transduction 28 (1-2), 93-108, 2008 | 66 | 2008 |
Cholinergic Stimulation of Amylase Secretion from Pancreatic Acinar Cells Studied with Muscarinic Acetylcholine Receptor Mutant Mice D Gautam, SJ Han, TS Heard, Y Cui, G Miller, L Bloodworth, J Wess Journal of Pharmacology and Experimental Therapeutics 313 (3), 995-1002, 2005 | 65 | 2005 |
Discovery of 3, 4-dihydropyrimidin-2 (1H)-ones with inhibitory activity against HIV-1 replication J Kim, C Park, T Ok, W So, M Jo, M Seo, Y Kim, JH Sohn, Y Park, MK Ju, ... Bioorganic & medicinal chemistry letters 22 (5), 2119-2124, 2012 | 62 | 2012 |
The endogenous siRNA pathway in Drosophila impacts stress resistance and lifespan by regulating metabolic homeostasis DH Lim, CT Oh, L Lee, JS Hong, SH Noh, S Hwang, S Kim, SJ Han, ... FEBS letters 585 (19), 3079-3085, 2011 | 61 | 2011 |
Hepatic muscarinic acetylcholine receptors are not critically involved in maintaining glucose homeostasis in mice JH Li, D Gautam, SJ Han, JM Guettier, Y Cui, H Lu, C Deng, J O'Hare, ... Diabetes 58 (12), 2776-2787, 2009 | 60 | 2009 |
In situ Visualization of Gene Expression Using Polymer‐Coated Quantum–Dot–DNA Conjugates Y Choi, HP Kim, SM Hong, JY Ryu, SJ Han, R Song Small 5 (18), 2085-2091, 2009 | 59 | 2009 |
Distinct structural changes in a G protein-coupled receptor caused by different classes of agonist ligands JH Li, SJ Han, FF Hamdan, SK Kim, KA Jacobson, LM Bloodworth, ... Journal of Biological Chemistry 282 (36), 26284-26293, 2007 | 59 | 2007 |
Lipopolysaccharide-activated kinase, an essential component for the induction of the antimicrobial peptide genes inDrosophila melanogaster cells YS Kim, SJ Han, JH Ryu, KH Choi, YS Hong, YH Chung, S Perrot, ... Journal of Biological Chemistry 275 (3), 2071-2079, 2000 | 57 | 2000 |