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Wenyi Wei
Wenyi Wei
Professor, Dept. of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School
Verified email at bidmc.harvard.edu
Title
Cited by
Cited by
Year
Bypass of Senescence After Disruption of p21CIP1/WAF1 Gene in Normal Diploid Human Fibroblasts
JP Brown, W Wei, JM Sedivy
Science 277 (5327), 831-834, 1997
10971997
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization
CM Counter, WC Hahn, W Wei, SD Caddle, RL Beijersbergen, ...
Proceedings of the National Academy of Sciences 95 (25), 14723-14728, 1998
8331998
Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance
J Zhang, X Bu, H Wang, Y Zhu, Y Geng, NT Nihira, Y Tan, Y Ci, F Wu, ...
Nature 553 (7686), 91-95, 2018
7722018
SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction
H Inuzuka, S Shaik, I Onoyama, D Gao, A Tseng, RS Maser, B Zhai, ...
Nature 471 (7336), 104-109, 2011
6902011
Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer
S Lee, E Nakamura, H Yang, W Wei, MS Linggi, MP Sajan, RV Farese, ...
Cancer cell 8 (2), 155-167, 2005
6342005
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
W Wei, NG Ayad, Y Wan, GJ Zhang, MW Kirschner, WG Kaelin Jr
Nature 428 (6979), 194-198, 2004
5622004
The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase
W Wei, J Jin, S Schlisio, JW Harper, WG Kaelin
Cancer cell 8 (1), 25-33, 2005
4902005
Roles of F-box proteins in cancer
Z Wang, P Liu, H Inuzuka, W Wei
Nature reviews Cancer 14 (4), 233-247, 2014
4882014
The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis
CH Chan, CF Li, WL Yang, Y Gao, SW Lee, Z Feng, HY Huang, KKC Tsai, ...
Cell 149 (5), 1098-1111, 2012
4192012
The role of ubiquitination in tumorigenesis and targeted drug discovery
L Deng, T Meng, L Chen, W Wei, P Wang
Signal transduction and targeted therapy 5 (1), 11, 2020
4092020
PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex
P Liu, W Gan, YR Chin, K Ogura, J Guo, J Zhang, B Wang, J Blenis, ...
Cancer discovery 5 (11), 1194-1209, 2015
3972015
Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus
P Liu, M Begley, W Michowski, H Inuzuka, M Ginzberg, D Gao, P Tsou, ...
Nature 508 (7497), 541-545, 2014
3782014
Role of p21 in apoptosis and senescence of human colon cancer cells treated with camptothecin
Z Han, W Wei, S Dunaway, JW Darnowski, P Calabresi, J Sedivy, ...
Journal of Biological Chemistry 277 (19), 17154-17160, 2002
3122002
Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function
A Papa, L Wan, M Bonora, L Salmena, MS Song, RM Hobbs, A Lunardi, ...
Cell 157 (3), 595-610, 2014
3072014
Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis
P Liu, W Gan, H Inuzuka, AS Lazorchak, D Gao, O Arojo, D Liu, L Wan, ...
Nature cell biology 15 (11), 1340-1350, 2013
3002013
Role of p14ARF in Replicative and Induced Senescence of Human Fibroblasts
W Wei, RM Hemmer, JM Sedivy
Molecular and cellular biology 21 (20), 6748-6757, 2001
2882001
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction
D Gao, H Inuzuka, A Tseng, RY Chin, A Toker, W Wei
Nature cell biology 11 (4), 397-408, 2009
2802009
Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4
X Dai, W Gan, X Li, S Wang, W Zhang, L Huang, S Liu, Q Zhong, J Guo, ...
Nature medicine 23 (9), 1063-1071, 2017
2782017
Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase
Z Wang, N Bhattacharya, PF Mixter, W Wei, J Sedivy, NS Magnuson
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1593 (1), 45-55, 2002
2772002
mTOR drives its own activation via SCFβTrCP-dependent degradation of the mTOR inhibitor DEPTOR
D Gao, H Inuzuka, MKM Tan, H Fukushima, JW Locasale, P Liu, L Wan, ...
Molecular cell 44 (2), 290-303, 2011
2692011
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