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Megan Capozzi
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Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist
FS Willard, JD Douros, MBN Gabe, AD Showalter, DB Wainscott, ...
JCI insight 5 (17), 2020
2182020
β Cell tone is defined by proglucagon peptides through cAMP signaling
ME Capozzi, B Svendsen, SE Encisco, SL Lewandowski, MD Martin, ...
JCI insight 4 (5), 2019
2032019
Glucagon lowers glycemia when β cells are active
ME Capozzi, JB Wait, J Koech, AN Gordon, RW Coch, B Svendsen, ...
JCI insight 4 (16), 2019
1262019
Targeting the incretin/glucagon system with triagonists to treat diabetes
ME Capozzi, RD DiMarchi, MH Tschöp, B Finan, JE Campbell
Endocrine reviews 39 (5), 719-738, 2018
1262018
Pyruvate kinase controls signal strength in the insulin secretory pathway
SL Lewandowski, RL Cardone, HR Foster, T Ho, E Potapenko, C Poudel, ...
Cell metabolism 32 (5), 736-750. e5, 2020
1032020
Repositioning glucagon action in the physiology and pharmacology of diabetes
B Finan, ME Capozzi, JE Campbell
Diabetes 69 (4), 532-541, 2020
902020
GIP mediates the incretin effect and glucose tolerance by dual actions on α cells and β cells
K El, SM Gray, ME Capozzi, ER Knuth, E Jin, B Svendsen, A Clifford, ...
Science advances 7 (11), eabf1948, 2021
812021
Inactivation of the glucose-dependent insulinotropic polypeptide receptor improves outcomes following experimental myocardial infarction
JR Ussher, JE Campbell, EE Mulvihill, LL Baggio, HE Bates, BA McLean, ...
Cell metabolism 27 (2), 450-460. e6, 2018
622018
Circadian perinatal photoperiod has enduring effects on retinal dopamine and visual function
CR Jackson, M Capozzi, H Dai, DG McMahon
Journal of Neuroscience 34 (13), 4627-4633, 2014
502014
Modulation of VEGF-induced retinal vascular permeability by peroxisome proliferator-activated receptor-β/δ
S Suarez, GW McCollum, CA Bretz, R Yang, ME Capozzi, JS Penn
Investigative ophthalmology & visual science 55 (12), 8232-8240, 2014
472014
Pimozide alleviates hyperglycemia in diet-induced obesity by inhibiting skeletal muscle ketone oxidation
R Al Batran, K Gopal, ME Capozzi, JJ Chahade, B Saleme, ...
Cell Metabolism 31 (5), 909-919. e8, 2020
462020
Epoxygenated fatty acids inhibit retinal vascular inflammation
ME Capozzi, SS Hammer, GW McCollum, JS Penn
Scientific reports 6 (1), 39211, 2016
462016
Sustained release of a GLP-1 and FGF21 dual agonist from an injectable depot protects mice from obesity and hyperglycemia
CA Gilroy, ME Capozzi, AK Varanko, J Tong, DA D'alessio, JE Campbell, ...
Science advances 6 (35), eaaz9890, 2020
452020
The limited role of glucagon for ketogenesis during fasting or in response to SGLT2 inhibition
ME Capozzi, RW Coch, J Koech, II Astapova, JB Wait, SE Encisco, ...
Diabetes 69 (5), 882-892, 2020
452020
Pharmacological antagonism of the incretin system protects against diet-induced obesity
B Svendsen, ME Capozzi, J Nui, SA Hannou, B Finan, J Naylor, P Ravn, ...
Molecular metabolism 32, 44-55, 2020
422020
The role of cytochrome P450 epoxygenases in retinal angiogenesis
ME Capozzi, GW McCollum, JS Penn
Investigative ophthalmology & visual science 55 (7), 4253-4260, 2014
422014
Molecular probes for imaging of hypoxia in the retina
SM Evans, K Kim, CE Moore, MI Uddin, ME Capozzi, JR Craft, ...
Bioconjugate chemistry 25 (11), 2030-2037, 2014
412014
Enhanced glucose control following vertical sleeve gastrectomy does not require a β-cell glucagon-like peptide 1 receptor
JD Douros, AG Lewis, EP Smith, JJ Niu, M Capozzi, A Wittmann, ...
Diabetes 67 (8), 1504-1511, 2018
362018
Hypoxia-induced expression of VEGF splice variants and protein in four retinal cell types
WM Watkins, GW McCollum, SR Savage, ME Capozzi, JS Penn, ...
Experimental eye research 116, 240-246, 2013
352013
Discordance between GLP-1R gene and protein expression in mouse pancreatic islet cells
SM Gray, Y Xin, EC Ross, BM Chazotte, ME Capozzi, K El, B Svendsen, ...
Journal of Biological Chemistry 295 (33), 11529-11541, 2020
302020
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