John Reyes Ussher
John Reyes Ussher
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta
Verified email at ualberta.ca
Title
Cited by
Cited by
Year
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
TR Koves, JR Ussher, RC Noland, D Slentz, M Mosedale, O Ilkayeva, ...
Cell metabolism 7 (1), 45-56, 2008
15442008
Myocardial fatty acid metabolism in health and disease
GD Lopaschuk, JR Ussher, CDL Folmes, JS Jaswal, WC Stanley
Physiological Reviews 90 (1), 207-258, 2010
14452010
Cardiovascular Biology of the Incretin System
JR Ussher, DJ Drucker
Endocrine Reviews, 2012
5402012
Targeting fatty acid and carbohydrate oxidation-A novel therapeutic intervention in the ischemic and failing heart
JS Jaswal, W Keung, W Wang, JR Ussher, GD Lopaschuk
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 2011
3182011
Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption
JR Ussher, TR Koves, VJJ Cadete, L Zhang, JS Jaswal, SJ Swyrd, ...
Diabetes 59 (10), 2453-2464, 2010
2862010
Cardiovascular actions of incretin-based therapies
JR Ussher, DJ Drucker
Circulation research 114 (11), 1788-1803, 2014
2702014
Gut microbiota metabolism of L-carnitine and cardiovascular risk
JR Ussher, GD Lopaschuk, A Arduini
Atherosclerosis 231 (2), 456-461, 2013
1442013
Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury
JR Ussher, W Wang, M Gandhi, W Keung, V Samokhvalov, T Oka, ...
Cardiovascular research 94 (2), 359-369, 2012
1442012
Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function
R Basu, GY Oudit, X Wang, L Zhang, JR Ussher, GD Lopaschuk, Z Kassiri
American Journal of Physiology-Heart and Circulatory Physiology 297 (6 …, 2009
1422009
Cardiac insulin-resistance and decreased mitochondrial energy production precede the development of systolic heart failure after pressure-overload hypertrophy
L Zhang, JS Jaswal, JR Ussher, S Sankaralingam, C Wagg, M Zaugg, ...
Circulation: Heart Failure 6 (5), 1039-1048, 2013
1332013
Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet–Induced Obese Mice Lacking Malonyl CoA Decarboxylase
JR Ussher, TR Koves, JS Jaswal, L Zhang, O Ilkayeva, JRB Dyck, ...
Diabetes 58 (8), 1766-1775, 2009
1172009
The emerging role of metabolomics in the diagnosis and prognosis of cardiovascular disease
JR Ussher, S Elmariah, RE Gerszten, JRB Dyck
Journal of the American College of Cardiology 68 (25), 2850-2870, 2016
1052016
Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation
L Zhang, JR Ussher, T Oka, VJJ Cadete, C Wagg, GD Lopaschuk
Cardiovascular research 89 (1), 148-156, 2011
1052011
Inhibition of carnitine palmitoyltransferase-1 activity alleviates insulin resistance in diet-induced obese mice
W Keung, JR Ussher, JS Jaswal, M Raubenheimer, VHM Lam, CS Wagg, ...
Diabetes 62 (3), 711-720, 2013
1012013
Lipotoxicity in obesity and diabetes-related cardiac dysfunction
I Zlobine, K Gopal, JR Ussher
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016
982016
The malonyl CoA axis as a potential target for treating ischaemic heart disease
JR Ussher, GD Lopaschuk
Cardiovascular research 79 (2), 259-268, 2008
972008
Inactivation of the cardiomyocyte glucagon-like peptide-1 receptor (GLP-1R) unmasks cardiomyocyte-independent GLP-1R-mediated cardioprotection
JR Ussher, LL Baggio, JE Campbell, EE Mulvihill, M Kim, MG Kabir, ...
Molecular metabolism 3 (5), 507-517, 2014
832014
Targeting malonyl CoA inhibition of mitochondrial fatty acid uptake as an approach to treat cardiac ischemia/reperfusion
JR Ussher, GD Lopaschuk
Basic research in cardiology 104 (2), 203-210, 2009
772009
Targeting intermediary metabolism in the hypothalamus as a mechanism to regulate appetite
GD Lopaschuk, JR Ussher, JS Jaswal
Pharmacological Reviews 62 (2), 237-264, 2010
732010
TCF1 links GIPR signaling to the control of beta cell function and survival
JE Campbell, JR Ussher, EE Mulvihill, J Kolic, LL Baggio, X Cao, Y Liu, ...
Nature medicine 22 (1), 84-90, 2016
712016
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